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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">perinatology</journal-id><journal-title-group><journal-title xml:lang="ru">Российский вестник перинатологии и педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1027-4065</issn><issn pub-type="epub">2500-2228</issn><publisher><publisher-name>Ltd. “The National Academy of Pediatric Science and Innovation”</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">perinatology-111</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Мембрана жировых глобул молока: инновационные открытия уже сегодня</article-title><trans-title-group xml:lang="en"><trans-title>Milk fat globule membrane: Innovation discoveries just for today</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., проф., зав. кафедрой педиатрии Российская медицинская академия последипломного образования, гл. педиатр ЦФО РФ, член Европейского общества педиатров, гастроэнтерологов и детских гепатологов (ESPGHAN), член Европейского общества иммунологов и аллергологов (EAACI).</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дмитриева</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dmitrieva</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент той же кафедры, член Европейского общества педиатров, гастроэнтерологов и детских гепатологов (ESPGHAN).</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гордеева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gordeeva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., врач-педиатр. 125993 Москва, ул. Баррикадная, д. 2/1, стр. 1</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ДПО «Российская медицинская академия последипломного образования» МЗ РФ, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>13</day><month>03</month><year>2016</year></pub-date><volume>60</volume><issue>6</issue><fpage>15</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ltd. “The National Academy of Pediatric Science and Innovation”, 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><copyright-holder xml:lang="en">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><license xlink:href="https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://www.ped-perinatology.ru/jour/article/view/111">https://www.ped-perinatology.ru/jour/article/view/111</self-uri><abstract><p>Пересматриваются существовавшие ранее требования к продуктам питания для младенцев с учетом новых результатов исследования состава и свойств грудного молока. Необходимость перевода детей на искусственное вскармливание требует совершенствования производства продуктов и их максимального приближения к составу молока кормящей женщины. Особый интерес привлекает возможность оптимизации жирового компонента молочных смесей для вскармливания здоровых детей. Ранее процесс адаптации жирового компонента молочных смесей был направлен на обогащение продуктов незаменимыми полиненасыщенными жирными кислотами за счет полного удаления молочного жира и введения в смесь комплекса растительных масел, являющихся источниками арахидоновой и докозагексаеновой кислот. Особое внимание в настоящее время обращено на так называемые «минорные» составляющие жирового компонента грудного молока, в частности, на жировые глобулы, центральная часть которых представлена гидрофобными триглицеридами, составляющими 95—98% глобулы. Остальные 2-5% глобулы представлены липидно-белковой мембраной, включающей также небольшие количества витаминов, ферментов. Данная мембрана получила название мембраны жировых глобул молока (MFGM), ее компоненты незаменимы для полноценного развития ребенка. Обогащение молочных смесей для вскармливания детей первого года жизни комплексными липидами в составе мембраны жировых глобул молока является перспективным направлением дальнейшего совершенствования производства продуктов детского питания.</p></abstract><trans-abstract xml:lang="en"><p>The previous requirements for baby foods are reconsidered with regards to the novel results of an investigation of breastmilk composition and properties. The need to switch babies over to formula feeding requires that the foods should be better manufactured and brought much closer to the milk of a breastfeeding mother. The possibility of optimizing the fat fraction of milk formulas for healthy babies is of particular interest. The adaptation of the fat fraction of milk formulas was previously aimed at fortifying the foods with essential polyunsaturated fatty acids, by removing butterfat completely and adding to the formula a complex of vegetable oils that are sources of arachidonic and docosahexaenic acids. Special attention is now drawn to the so-called minor components of the fat fraction of breast milk, its fat globules in particular, the core of which is present as hydrophobic triglycerides comprising 95-98% of the globules. The remaining 2-5% of the globules is the lipid-protein membrane that also contains small amounts of vitamins and enzymes. This membrane is named milk fat globule membrane (MFGM); its components are indispensable for the adequate development of a child. To fortify milk formulas with complex lipids as a MFGM component for babies during the first year of life is a promising area for the further improvement of the manufacture of infant foods.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>младенцы</kwd><kwd>ранний возраст</kwd><kwd>вскармливание</kwd><kwd>пищевое программирование</kwd><kwd>метаболизм</kwd><kwd>грудное молоко</kwd><kwd>искусственная смесь</kwd><kwd>длинноцепочечные полиненасыщенные жирные кислоты</kwd><kwd>арахидоновая</kwd><kwd>кислота</kwd><kwd>докозагексаено-вая кислота</kwd><kwd>фосфолипиды</kwd><kwd>ганглиозиды</kwd><kwd>холестерин</kwd><kwd>клеточные мембраны</kwd><kwd>компоненты мембран жировых глобул молока (MFGM)</kwd><kwd>физическое и нервно-психическое развитие</kwd><kwd>зрительный анализатор.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>babies</kwd><kwd>infancy</kwd><kwd>infant feeding</kwd><kwd>eating programming</kwd><kwd>metabolism</kwd><kwd>breast milk</kwd><kwd>formula</kwd><kwd>long-chain polyunsaturated fatty acids</kwd><kwd>arachidonic acid</kwd><kwd>docosahexaenic acid</kwd><kwd>phospholipids</kwd><kwd>gangliosides</kwd><kwd>cholesterol</kwd><kwd>cell membranes</kwd><kwd>milk fat globule membrane components</kwd><kwd>physical and neuropsychiatric development</kwd><kwd>visual analyzer.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Захарова И.Н., Дмитриева Ю.А., Суркова Е.Н. 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