perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2020-65-5-31-36perinatology-1231Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWSАнафилаксия и витамин D: ассоциации и перспективыAnaphylaxis and vitamin D: associations and perspectiveshttps://orcid.org/0000-0003-4200-4598ЗахароваИ. Н.ZakharovaI. N.

Захарова Ирина Николаевна — доктор медицинских наук, профессор, заведующий кафедрой педиатрии с курсом поликлинической педиатрии им. академика Г.Н. Сперанского.

Москва

Moscow

zakharova-rmapo@yandex.ruhttps://orcid.org/0000-0001-5039-8473ПампураА. Н.PampuraA. N.

Пампура Александр Николаевич – доктор медицинских наук, профессор кафедры педиатрии с курсом поликлинической педиатрии им. Г.Н. Сперанского.

125412 Москва, ул. Талдомская, д. 2

Moscow

https://orcid.org/0000-0002-7994-3751СимаковаМ. А.SimakovaM. A.

Симакова Мария Александровна — аспирант кафедры педиатрии с курсом поликлинической педиатрии им. академика Г.Н. Сперанского.

Москва

Moscow

https://orcid.org/0000-0002-0731-7153КурьяниноваВ. А.KuryaninovaV. A.

Курьянинова Виктория Александровна – кандидат медицинских наук, доцент кафедры пропедевтики детских болезней

https://orcid.org/0000-0001-7248-1614КлимовЛ. Я.KlimovL. Ja.

Климов Леонид Яковлевич – доктор медицинских наук, доцент, зав. кафедрой факультетской педиатрии.

355017 Ставрополь, ул. Мира, д. 310

https://orcid.org/0000-0002-4496-3680СычевД. А.SychevD. A.

Сычев Дмитрий Алексеевич — чл.-корр. РАН, доктор медицинских наук, профессор, ректор, зав. кафедрой клинической фармакологии и терапии.

123242 Москва, ул. Баррикадная, д. 2/1

Moscow

ФГБОУ ДПО Российская медицинская академия непрерывного профессионального образования Минздрава РоссииРоссияRussian Medical Academy of Continuous Professional EducationRussian FederationФГБОУ ДПО Российская медицинская академия непрерывного профессионального образования Минздрава России; ОСП Научно-исследовательский клинический институт педиатрии им. академика Ю.Е. Вельтищева, ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава РоссииРоссияRussian Medical Academy of Continuous Professional EducationRussian FederationФГБОУ ВО Ставропольский государственный медицинский университет Минздрава РоссииРоссияStavropol State Medical UniversityRussian Federation2020181120206553136Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20202020Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/1231

Во всем мире наблюдается тенденция к росту числа острых системных аллергических реакций, особенно связанных с пищевой аллергией. В ряде исследований зафиксирована связь между распространенностью анафилаксии в популяции и географическим расположением (географической широтой) проживания изучаемой выборки пациентов. Это позволило выдвинуть гипотезу о связи снижения частоты развития анафилаксии с более высоким содержанием витамина D в организме. В настоящее время механизмы, посредством которых витамин D влияет на развитие аллергических заболеваний, до конца не изучены. Эффективность дополнительного приема витамина D в профилактике и лечении атопического дерматита и бронхиальной астмы остается дискутабельной. В статье проанализированы результаты исследований, оценивших возможную ассоциацию между обеспеченностью организма витамином D и анафилаксией.

Worldwide there is a tendency of increasing acute systemic allergic reactions, especially those associated with food allergies. Numerous studies have revealed a relationship between the prevalence of anaphylaxis in the population and the geographical location (latitude) of the patient. This fact produced the hypothesis of an association between the anaphylaxis frequency reduction due to the higher contents of vitamin D. At the moment the role of vitamin D has not been fully studied in the development of allergic diseases. The effectiveness of additional vitamin D in the prevention and treatment of atopic dermatitis and bronchial asthma remains debatable. The article analyzes the data of possible association between vitamin D and anaphylaxis.

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The authors declare that there are no conflicts of interest present.