perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2020-65-5-209-214perinatology-1261Research ArticleК XVII РОССИЙСКОМУ КОНГРЕССУ «ПЕДИАТРИЯ И ДЕТСКАЯ ХИРУРГИЯ В ПРИВОЛЖСКОМ ФЕДЕРАЛЬНОМ ОКРУГЕ». КЛИНИЧЕСКИЕ СЛУЧАИTO THE XVI RUSSIAN CONGRESS «PEDIATRICS AND PEDIATRIC SURGERY IN THE PRIVOLZHSKY FEDERAL DISTRICT». CLINICAL CASESАнтифосфолипидный синдром у беременной и глобальная церебральная ишемия у новорожденного: есть ли связь?Antiphospholipid syndrome in a pregnant woman and global cerebral ischemia in a newborn: are they connected?https://orcid.org/0000-0002-4255-9107ГайнетдиноваД. Д.GaynetdinovaD. D.

Гайнетдинова Дина Дамировна — доктор медицинских наук, профессор кафедры неврологии, нейрохирургии и медицинской генетики.

420012 Казань, ул. Бутлерова, д. 49

anetdina@mail.ruhttps://orcid.org/0000-0003-4941-4186НовоселоваА. А.NovoselovaA. A.

Новоселова Анастасия Андреевна — студентка V курса педиатрического факультета.

420012 Казань, ул. Бутлерова, д. 49

ФГБОУ ВО Казанский государственный медицинский университет Минздрава РоссииРоссияKazan State Medical UniversityRussian Federation202021112020655209214Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20202020Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/1261

Церебральная ишемия — наиболее распространенная патология центральной нервной системы у новорожденных, а ее нервно-психические последствия служат причиной первичной детской инвалидности. Глобальная церебральная ишемия у новорожденного может развиться вследствие нарушения фетоплацентарного кровотока при антифосфолипидном синдроме у беременной женщины. Рассматривается участие антифосфолипидных антител в патогенезе гипоксически-ишемического поражения головного мозга плода и новорожденного ребенка. Представлено клиническое наблюдение пациента со спастическим церебральным параличом и отставанием психомоторного развития у матери с антифосфолипидным синдромом.

Cerebral ischemia is the most common pathology of the central nervous system in newborns, and its neuropsychological consequences cause child disability. The global cerebral ischemia in a newborn may be caused by a violation of fetoplacental blood flow in pregnant woman with antiphospholipid syndrome. The article considers the role of antiphospholipid antibodies in the pathogenesis of hypoxice-mia-ischemic brain damage of the fetus and newborn child. The authors present a clinical case of a patient with spastic cerebral palsy and delayed psychomotor development born from a mother with antiphospholipid syndrome.

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The authors declare that there are no conflicts of interest present.