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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">perinatology</journal-id><journal-title-group><journal-title xml:lang="ru">Российский вестник перинатологии и педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1027-4065</issn><issn pub-type="epub">2500-2228</issn><publisher><publisher-name>Ltd. “The National Academy of Pediatric Science and Innovation”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21508/1027-4065-2021-66-4-9-44</article-id><article-id custom-type="elpub" pub-id-type="custom">perinatology-1442</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Кесарево сечение при тяжелой преэклампсии: особенности ранней неонатальной адаптации</article-title><trans-title-group xml:lang="en"><trans-title>Caesarean section in severe preeclampsia: features of early neonatal adaptation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0271-4475</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исаева</surname><given-names>Э. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Isaeva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Исаева Элеонора Владимировна – науч. сотр. Кыргызского научного центра репродукции человека</p><p>720028 Бишкек, мкр. 7, д. 14/1</p></bio><bio xml:lang="en"><p>Bishkek</p></bio><email xlink:type="simple">isaevaeleonora@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8935-366X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыскельдиева</surname><given-names>В. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ryskeldieva</surname><given-names>V. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рыскельдиева Виктория Турарбековна – д.м.н., дир.</p><p>720028 Бишкек, мкр. 7, д. 14/1</p></bio><bio xml:lang="en"><p>Bishkek</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кыргызский научный центр репродукции человека</institution><country>Кыргызстан</country></aff><aff xml:lang="en"><institution>Kyrgyz Scientific Center of Human Reproduction</institution><country>Kyrgyzstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>27</day><month>09</month><year>2021</year></pub-date><volume>66</volume><issue>4</issue><fpage>39</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ltd. “The National Academy of Pediatric Science and Innovation”, 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><copyright-holder xml:lang="en">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><license xlink:href="https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://www.ped-perinatology.ru/jour/article/view/1442">https://www.ped-perinatology.ru/jour/article/view/1442</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Изучение особенностей течения ранней неонатальной адаптации в зависимости от метода анестезиологического пособия при абдоминальном родоразрешении беременных с тяжелой преэклампсией. Характеристика детей и методы исследования. Проведено когортное проспективное исследование, в которое были включены 342новорожденных от матерей с преэклампсией тяжелой степени. Дети были распределены в группы в соответствии с периодом гестации. Проанализированы перинатальные потери, проведен анализ оценокобщего состояния по шкале Апгар на 1-й и 5-й минутах жизни, а также неврологического статуса новорожденных по шкале NACS на 15-й минуте жизни и через2 ч в зависимости от примененного во время кесарева сечения метода анестезии.</p></sec><sec><title>Результаты</title><p>Результаты. У новорожденных, начиная с 34-й недели гестации, установлено достоверно более выраженное негативное влияние тотальной внутривенной анестезии на соматический (рождение в состоянии гипоксии) и неврологический статус новорожденных от матерей с преэклампсией тяжелой степени по сравнению со спинномозговой анестезией (р&lt;0,05).</p></sec><sec><title>Заключение</title><p> Заключение. Полученные результаты могут иметь практическую ценность для неонатологов, так как при применении тотальной внутривенной анестезии выявленные нарушения адаптационной способности новорожденных ожидаемы и дают возможность врачу своевременно оказать детям адекватную помощь.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. To study the course of early neonatal adaptation depending on the anesthetic aid in abdominaldelivery of pregnant women with severe preeclampsia. Characteristic o fchildren and research methods. Thea uthorscarried outaprospective cohort study o f342 childrenborn from mothers with severepreeclampsia. The children were grouped according to their gestationalage. The author sanalyzed perinatallosse sand assessed  general condition according to the Apgarscaleat the 1st and 5th minutes of life, aswell as the neurological status of newborns according to the NACS scale at the 15thminute of life and in 2 hours depending on the anesthesia method used during the caesareansection.</p></sec><sec><title>Results</title><p>Results. The authors found that the newborns from mothers with severe preeclampsia, starting from the 34th week of gestation, demonstrated a significantly more pronounced negative effect of total intravenous anesthesia on their somatic (birth in a state of hypoxia) and neurological status as compared with spinalanesthesia (р&lt;0,05). &gt;&lt;0,05).</p></sec><sec><title>Conclusion</title><p>Conclusion. The results are of practical value to neonatologists, as total intravenous anesthesia is expectedto causethe revealed violations of the adaptive ability of newborns and the doctor is able to provide adequate timely assistance to children.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>новорожденные</kwd><kwd>преэклампсия тяжелой степени</kwd><kwd>кесарево сечение</kwd><kwd>метод анестезиологического обеспечения</kwd><kwd>перинатальные исходы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>newborns</kwd><kwd>severe preeclampsia</kwd><kwd>cesarean section</kwd><kwd>anesthetic method</kwd><kwd>perinatal outcomes</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">WHO recommendations non-clinical interventions to reduce unnecessary caesarean sections. Geneva: World Health Organization; 2018; 79. 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