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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">perinatology</journal-id><journal-title-group><journal-title xml:lang="ru">Российский вестник перинатологии и педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1027-4065</issn><issn pub-type="epub">2500-2228</issn><publisher><publisher-name>Ltd. “The National Academy of Pediatric Science and Innovation”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21508/1027-4065-2021-66-5-141-149</article-id><article-id custom-type="elpub" pub-id-type="custom">perinatology-1494</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FOR THE PRACTITIONER</subject></subj-group></article-categories><title-group><article-title>Клинические проявления и дифференциальный диагноз атопического дерматита у детей раннего возраста</article-title><trans-title-group xml:lang="en"><trans-title>Clinical manifestations and differential diagnosis of atopic dermatitis in young children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6890-2041</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Боткина</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Botkinа</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Боткина Александра Сергеевна – к.м.н., доц. кафедры госпитальной педиатрии им. акад. В.А. Таболина педиатрического факультета</p><p>117997 Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">botkina@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3487-2451</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дубровская</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Dubrovskaya</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дубровская Мария Игоревна – д.м.н., проф. кафедры госпитальной педиатрии им. акад. В.А. Таболина педиатрического факультета</p><p>117997 Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1704-2456</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Моисеев</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Moiseev</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Моисеев Анатолий Борисович – д.м.н., зав. кафедрой пропедевтики детских болезней педиатрического факультета</p><p>117997 Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9999-7634</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вартапетова</surname><given-names>Е. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Vartapetova</surname><given-names>E. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Вартапетова Екатерина Евгеньевна – к.м.н., доц. кафедры пропедевтики детских болезней</p><p>117997 Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>09</day><month>12</month><year>2021</year></pub-date><volume>66</volume><issue>5</issue><fpage>141</fpage><lpage>149</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ltd. “The National Academy of Pediatric Science and Innovation”, 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><copyright-holder xml:lang="en">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><license xlink:href="https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://www.ped-perinatology.ru/jour/article/view/1494">https://www.ped-perinatology.ru/jour/article/view/1494</self-uri><abstract><p>Атопический дерматит – одно из наиболее распространенных дерматологических заболеваний детей грудного и раннего детского возраста. Заболевание имеет хроническое рецидивирующее течение и характеризуется зудом, эритемой, лихенификацией и шелушением. В типичных случаях диагноз устанавливается клинически на основании имеющихся диагностических критериев. Однако аналогичные клинические проявления встречаются и при ряде других заболеваний, которые могут имитировать, сопутствовать или осложнять течение атопического дерматита. К ним относятся воспалительные состояния кожи, инфекции, паразитарные заболевания, генодерматозы, иммунодефициты и злокачественные новообразования, а также нарушения питания, болезнь трансплантат против хозяина и лекарственная болезнь. Знание спектра этих заболеваний и их отличительных особенностей имеет решающее значение для правильной и своевременной диагностики атопического дерматита, подбора оптимального лечения.</p></abstract><trans-abstract xml:lang="en"><p>Atopic dermatitis is one of the most common dermatological diseases in infants and young children. The disease is characterized by a chronic recurrent course with itching, erythema, lichenification and desquamation. Typical cases are diagnosed on the clinically available diagnostic criteria. However, similar clinical manifestations are found in a number of other diseases that can simulate, accompany or complicate the course of atopic dermatitis. They include inflammatory skin conditions, infections, parasitic diseases, genodermatoses, immunodeficiencies and malignancies, as well as nutritional disorders, graft-versus-host disease, and drug disease. Knowledge of the spectrum of these diseases and their distinctive features is crucial for the correct and timely diagnosis of atopic dermatitis, the selection of the optimal treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>атопический дерматит</kwd><kwd>дифференциальный диагноз</kwd><kwd>ранний детский возраст</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>atopic dermatitis</kwd><kwd>differential diagnosis</kwd><kwd>early childhood</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pawankar R., Canonica G.W., Holgate S.T., Richard F.L. On behalf of the World Allergy Organization (WAO), the authors of the WAO White Book on Allergy 2011–2012: Executive Summary express their gratitude to the charity, Asthma, Allergy, and Inflammation Research (AAIR) for support in the production of this publication. 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