perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2022-67-2-12-19perinatology-1613Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSПрогноз сердечно-сосудистых осложнений и прогрессирования почечной недостаточности у педиатрических пациентов с хронической болезнью почек в соответствии с классификациями NKF-K/DOQI (2002) и KDIGO (2012)Prediction of cardiovascular complications and progression of renal failure in pediatric patients with chronic kidney disease according to NKF-K/DOQI (2002) and KDIGO (2012) classificationshttps://orcid.org/0000-0002-9415-4785СавенковаН. Д.SavenkovaN. D.

Савенкова Надежда Дмитриевна — д.м.н., проф., зав. кафедрой факультетской педиатрии

194100 Санкт-Петербург, ул. Литовская, д. 2

Saint Petersburg

https://orcid.org/0000-0003-4353-2237ГригорьеваО. П.GrigorievaO. P.

Григорьева Ольга Павловна — к.м.н., асс. кафедры факультетской педиатрии

194100 Санкт-Петербург, ул. Литовская, д. 2

Saint Petersburg

ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Минздрава РоссииРоссияSaint Petersburg State Pediatric Medical UniversityRussian Federation2022070620226721219Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20222022Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/1613

Хроническая болезнь почек у педиатрических и взрослых пациентов представляет мировую глобальную проблему. Стратификация тяжести хронической болезни почек С1–5 по классификациям National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative (NKF-K/DOQI; 2002) и Kidney disease improving global outcomes (KDIGO; 2012) осуществляется у педиатри- ческих пациентов в возрасте старше 2 лет с учетом низкой скорости клубочковой фильтрации в возрасте от 0 до 2 лет. Установлены различия прогноза сердечно-сосудистых осложнений и прогрессирования почечной недостаточности у взрослых пациентов с хронической болезнью почек на стадиях С3а и С3б по KDIGO (2012). Данные литературы демонстрируют различные риски развития сердечно-сосудистых осложнений и прогрессирования дисфункции почек по стадиям хронической болезни почек в соответствии с классификациями NKF-K/DOQI (2002) и KDIGO (2012) у педиатрических пациентов. Результаты свидетельствуют, что дети с хронической болезнью почек на додиализных стадиях (С2–4) формируют группу высокого риска; дети, находящиеся на диализе (С4–5), — группу очень высокого риска развития сердечно-сосудистых осложнений.

Chronic kidney disease in pediatric and adult patients is an overarching global problem. Stratification of chronic kidney disease C1–5 severity by classifications of the National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative (NKF-K/DOQI) (2002) and Kidney Disease: Improving Global Outcomes (KDIGO) (2012) carried out in pediatric patients over the age of 2 years old, taking into account the low glomerular filtration rate at the age of 0 to 2 years. Differences were found in the prognosis of cardiovascular complications and the progression of renal failure in adult patients with chronic kidney disease at stages С3а and C3b according to KDIGO (2012). The literature data demonstrate different risks of cardiovascular complications and progression of renal functions by stages of chronic kidney disease in accordance with the NKF-K/DOQI (2002) and KDIGO (2012) classifications in pediatric patients. The results indicate that children with chronic kidney disease in the pre-dialysis stages C2–4 form a high-risk group, while those on C4–5 dialysis form a group of very high risk of cardiovascular complications.

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The authors declare that there are no conflicts of interest present.