perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2022-67-4-14-21perinatology-1669Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWSПерсонифицированная медицина: современные тенденции и перспективыPersonalized medicine: current trends and prospectshttps://orcid.org/0000-0001-9777-1220ДолгополовИ. С.DolgopolovI. S.

д.м.н., проректор по развитию регионального здравоохранения, зав. кафедрой педиатрии педиатрического факультета,

170100 Тверь, ул. Советская, 4

Tver

https://orcid.org/0000-0002-8398-7001РыковМ. Ю.RykovM. Yu.

д.м.н., доц., проректор по научной работе и инновационной деятельности, зав. кафедрой онкологии факультета дополнительного профессионального образования, 

170100 Тверь, ул. Советская, 4

Tver

wordex2006@rambler.ruФГБОУ ВО «Тверской государственный медицинский университет» Минздрава РоссииРоссияTver State Medical UniversityRussian Federation2022200920226741421Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20222022Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/1669

«Персонализированная» медицина основана на утверждении, что каждый человек обладает уникальными характеристиками на молекулярном, физиологическом, экологическом и поведенческом уровнях, и в случае развития болезни ее лечение следует проводить с учетом этих уникальных характеристик. Это убеждение было в некоторой степени подтверждено в процессе применения новейших технологий, таких как секвенирование ДНК, протеомика, протоколы визуализации и использования беспроводных устройств для мониторинга состояния здоровья, которые выявили большие межиндивидуальные различия. Проведен поиск источников литературы (научных статей), включая опубликованные в рецензируемых журналах, индексируемых в PubMed, Wos, Scopus и РИНЦ. В обзор включено 49 статей, посвященных персонализированной медицине. Рассматриваются новые технологии, которые делают возможной персонализированную медицину, новый опыт, способы проверки и применения индивидуализированных лекарств, а также потенциальные способы лечения людей с проблемами фертильности и бесплодия. Можно утверждать, что индивидуализация медицинской практики в определенных случаях, вероятно, неизбежна. Тем более что индивидуальный подход к пациенту становится более эффективным и рентабельным. 

«Personalized» medicine is based on the belief that each person has unique molecular, physiological, environmental, and behavioral characteristics, and in case of disease, each patient should be treated taking into account these unique characteristics. This belief was to some extent confirmed by the use of the latest technologies, such as DNA sequencing, proteomics, imaging protocols and the use of wireless devices for health monitoring, which revealed large inter-individual differences. Literary sources (scientific articles) were searched, including those published in peer-reviewed journals indexed in PubMed, Wos, Scopus, and the Russian Science Citation Index. The review includes 49 articles on personalized medicine. It explores new technologies that make personalized medicine possible, new experiences, ways to test and apply individualized drugs, and potential treatments for people with fertility and infertility issues. It can be argued that the individualization of medical practice in certain cases is probably inevitable. Moreover, an individual approach to a patient becomes more efficient and cost-effective. 

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The authors declare that there are no conflicts of interest present.