perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”perinatology-173Research ArticleМАТЕРИАЛЫ XII РОССИЙСКОЙ КОНФЕРЕНЦИИ «ПЕДИАТРИЯ И ДЕТСКАЯ ХИРУРГИЯ В ПРИВОЛЖСКОМ ФЕДЕРАЛЬНОМ ОКРУГЕ»МАТЕРИАЛЫ XII РОССИЙСКОЙ КОНФЕРЕНЦИИ «ПЕДИАТРИЯ И ДЕТСКАЯ ХИРУРГИЯ В ПРИВОЛЖСКОМ ФЕДЕРАЛЬНОМ ОКРУГЕ»Коклюш: актуальные вопросы эпидемиологии, диагностики и профилактикиPertussis: Topical issues of epidemiology, diagnosis, and preventionНиколаеваИ. В.NikolaevaI. V.

д.м.н.. доц. каф. детских инфекций Казанского государственного медицинского университета 420012 Казань, ул. Бутлерова, д. 49

ЦарегородцевА. Д.TsaregorodtsevA. D.

д.м.н., проф., советник РНИМУ им. Н.И. Пирогова 117997 Москва, ул. Островитянова, д. 1

Казанский государственный медицинский университет; ГБОУ ВПО РНИМУ им. Н.И. Пирогова, МоскваРоссияKazan State Medical University; N.I. Pirogov Russian National Research Medical University, MoscowRussian Federation201514032016605162167Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20162016Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/173

Несмотря на повсеместно проводимую вакцинацию, коклюш остается важной причиной младенческой заболеваемости и смертности. Ежегодно в мире им болеют около 16 млн человек и примерно 195 тыс. случаев у детей заканчивается летальным исходом. Однако только 5—10% всех случаев коклюша диагностируется и регистрируется. Во многих странах мира, несмотря на широкий охват вакцинацией, в настоящее время идет, фактически, эпидемия коклюша, причем значительную долю среди заболевших составляют привитые дети. Подростки и взрослые являются основным резервуаром циклических вспышек коклюша, однако болезнь у них диагностируется редко. В обзоре приведены мнения ученых о причинах данного явления и предлагаемых мерах по снижению заболеваемости в разных возрастных группах. Тяжелые и осложненные формы коклюша, а также летальные исходы развиваются у детей первых месяцев жизни, в связи с чем современная стратегия вакцинации должна быть направлена на предупреждение инфицирования именно данной возрастной группы детей.

Despite widespread vaccination, pertussis remains an important cause of infant morbidity and mortality. About 16 million people are ill with this disease and approximately 195 thousand children die worldwide every year. However, only 5—10% of all pertussis cases are diagnosed and notified. In spite of wide immunization coverage, there is really a pertussis epidemic in many countries of the world now; moreover, vaccinated children constitute a high proportion of disease cases. Adolescents and adults are a major reservoir for cyclic outbreaks of pertussis; however, they are rarely diagnosed with the disease. The review gives scientists' opinion on the causes of this phenomenon and proposed measures to reduce morbidity in different age groups. The severe and complicated forms of pertussis and fatal outcomes occur in babies during the first months of life and therefore current vaccination strategies should be aimed at preventing the infection just in this age group of children.

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The authors declare that there are no conflicts of interest present.