perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2023-68-2-39-46perinatology-1799Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSСовременные подходы к диагностике и ведению детей раннего возраста с аллергией на белки коровьего молокаModern approaches to the diagnosis and management of children with allergy to cow’s milk proteinshttps://orcid.org/0000-0001-5039-8473ПампураА. Н.PampuraA. N.

Пампура Александр Николаевич — доктор медицинских наук, заведующий отделом аллергологии и клинической иммунологии Научно-исследовательского клинического института педиатрии и детской хирургии им. академика Ю.Е. Вельтищева, главный внештатный детский специалист — аллерголог-иммунолог Департамента здравоохранения г. Москвы

125412 Москва, ул. Талдомская, д. 2

Moscow

apampura1@mail.ruhttps://orcid.org/0000-0002-4908-6146ЖукалинаЕ. Ф.ZhukalinaE. F.

Жукалина Евгения Федоровна — кандидат медицинских наук, врач–аллерголог-иммунолог поликлинического отделения 

115522 Москва, Каширское ш., д. 24

Moscow

https://orcid.org/0000-0001-9553-3560МоренкоМ. А.MorenkoM. A.

Моренко Марина Алексеевна — доктор медицинских наук, профессор, заведующая кафедрой детских болезней с курсами аллергологии, иммунологии, гематологии и эндокринологии Медицинского университета Астана, главный детский иммунолог Управления общественного здравоохранения г. Нур-Султана

010000 Астана, ул. Бейбитшилик, д. 49/A

Astana

https://orcid.org/0000-0002-5874-1624УсеноваО. П.UsenovaO. P.

Усенова Оксана Полатовна — врач–аллерголог-иммунолог, педиатр, магистр медицины, ассистент кафедры детских болезней с курсами аллергологии, иммунологии, гематологии и эндокринологии 

010000 Астана, ул. Бейбитшилик, д. 49/A

Astana

ОСП «Научно-исследовательский клинический институт педиатрии и детской хирургии им. академика Ю.Е. Вельтищева» ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава РоссииРоссияVeltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical UniversityRussian FederationФГБУ «Государственный научный центр Институт иммунологии» ФМБА РоссииРоссияInstitute of Immunology FMBA of RussiaRussian FederationНАО «Медицинский университет Астана»КазахстанAstana Medical UniversityKazakhstan2023270420236823946Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20232023Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/1799

Аллергия на белки коровьего молока — наиболее распространенная причина аллергических реакций у детей раннего возраста, оказывающая значительное влияние на качество жизни детей и их семей. Наиболее важным биомаркером аллергии к молоку травоядных является аллерген-специфический IgE (sIgE), который может быть оценен как к цельному аллергену (например, коровьему молоку, кобыльему молоку, козьему молоку и т.д.), так и к конкретной молекуле, входящей в их состав. Данная статья посвящена оценке sIgE у детей раннего возраста с подозрением на аллергию к белкам коровьего молока.

Allergy to cow’s milk proteins is the most common cause of allergic reactions in young children, with a significant impact on the quality of life of children and their families. The most significant biomarker of herbivore milk allergy is allergen-specific IgE (sIgE), which can be assessed both for the whole allergen (for example, cow’s milk (CM), mare’s milk, goat’s milk, etc.) and a specific molecule, included in their composition. This article focuses on the use of sIgE in infants with suspected cow’s milk protein allergy.

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The authors declare that there are no conflicts of interest present.