perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2023-68-5-119-125perinatology-1885Research ArticleКЛИНИЧЕСКИЕ СЛУЧАИCLINICAL CASESРедкий случай кожного мастоцитоза в практике педиатраA rare case of cutaneous mastocytosis in pediatric practicehttps://orcid.org/0000-0003-1741-2629КулаковаГ. А.KulakovaG. A.

Кулакова Галина Александровна — к.м.н., доц. кафедры госпитальной педиатрии 

420012 Казань, ул. Бутлерова, д. 49

Kazan

galinkul@mail.ruhttps://orcid.org/0000-0002-9687-4583СоловьеваН. А.SolovievaN. A.

Соловьева Наиля Анасовна — к.м.н., доц. кафедры госпитальной педиатрии 

420012 Казань, ул. Бутлерова, д. 49

Kazan

https://orcid.org/0000-0002-4147-2309ВолгинаС. Я.VolginaS. Ya.

Волгина Светлана Яковлевна — д.м.н., проф. кафедры госпитальной педиатрии 

420012 Казань, ул. Бутлерова, д. 49

Kazan

https://orcid.org/0000-0003-0873-8037КурмаеваЕ. А.KurmaevaE. A.

Курмаева Елена Анатольевна — к.м.н., доц. кафедры госпитальной педиатрии 

420012 Казань, ул. Бутлерова, д. 49

Kazan

https://orcid.org/0009-0004-3103-4083КалининаО. В.KalininaO. V.

Калинина Ольга Вадимовна — зам. гл. врача по медицинской части 

420103 Казань, пр. Ямашева, д. 48

Kazan

https://orcid.org/0009-0004-0283-3038КаюмоваИ. И.KaiumovaI. I.

Каюмова Илюза Ильгизовна — ординатор кафедры госпитальной педиатрии 

420012 Казань, ул. Бутлерова, д. 49

Kazan

https://orcid.org/0009-0001-4302-5326ЗарваЛ. А.ZarvaL. A.

Зарва Леонид Александрович — студент VI курса педиатрического факультета 

420012 Казань, ул. Бутлерова, д. 49

Kazan

ФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РоссииРоссияKazan State Medical UniversityRussian FederationГАУЗ «Детская поликлиника №7»РоссияChildren’s Polyclinic No.7Russian Federation202316112023685119125Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20232023Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/1885

Мастоцитоз относится к группе редких заболеваний, при которых происходит патологическое накопление тучных клеток в тканях. В детском возрасте чаще ограничивается поражением кожи. Представлен клинический случай буллезной формы кожного мастоцитоза с тяжелым течением, с дебютом заболевания в 3,5 мес. Кожные проявления с положительным симптомом Дарье–Унна и высокий уровень триптазы в крови, исключение системного поражения позволили диагностировать кожный мастоцитоз и выбрать тактику лечения.

Mastocytosis belongs to a group of rare diseases in which there is a pathological accumulation of mast cells in tissues. In childhood, it is more often limited to skin lesions. A clinical case of a bullous form of severe cutaneous mastocytosis, with the onset of the disease at 3.5 months, is presented. Cutaneous manifestations with a positive Darier–Unna symptom and a high level of tryptase in the blood, the exclusion of systemic lesions allowed diagnosing cutaneous mastocytosis and choosing treatment tactics.

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The authors declare that there are no conflicts of interest present.