perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2023-68-6-112-120perinatology-1914Research ArticleКЛИНИЧЕСКИЕ СЛУЧАИCLINICAL CASESАНЦА-ассоциированный васкулит с рецидивирующим тромбозом у подростка после новой коронавирусной инфекцииANCA-associated vasculitis with recurrent thrombosis in a teenager after the new coronavirus infectionhttps://orcid.org/0000-0002-2290-0013БалыковаЛ. А.BalykovaL. A.

Балыкова Лариса Александровна — д.м.н., проф., член-корр. РАН, дир. Медицинского института 

430000 Саранск, ул. Большевистская, д. 68/1

Saransk

larisabalykova@yandex.ruhttps://orcid.org/0000-0003-2927-3224СолдатовО. М.SoldatovO. M.

Солдатов Олег Михайлович — к.м.н., гл. врач

430032 Саранск, ул. Розы Люксембург, д. 15

Saransk

https://orcid.org/0000-0002-9462-3000РаздолькинаТ. И.RazdolkinaT. I.

Раздолькина Татьяна Ивановна — к.м.н., доц. кафедры педиатрии Медицинского института

430000 Саранск, ул. Большевистская, д. 68/1

Saransk

https://orcid.org/0000-0003-2927-3224ВерещагинаВ. С.VereshchaginaV. S.

Верещагина Вероника Сергеевна — к.м.н., доц. кафедры педиатрии Медицинского института

430000 Саранск, ул. Большевистская, д. 68/1

Saransk

https://orcid.org/0000-0002-9049-5662ШирманкинаМ. В.ShirmankinaM. V.

Ширманкина Марина Васильевна — ординатор кафедры педиатрии Медицинского института

430000 Саранск, ул. Большевистская, д. 68/1

Saransk

https://orcid.org/0000-0003-3990-9353КраснопольскаяА. В.KrasnopolskayaA. V.

Краснопольская Анна Валерьевна — к.м.н., ст. преподаватель кафедры педиатрии Медицинского института

430000 Саранск, ул. Большевистская, д. 68/1

Saransk

https://orcid.org/0000-0002-4504-7959МосковскаяЕ. Ф.MoskovskayaE. F.

Московская Елена Федоровна — зав. нефрологическим отделением

430032 Саранск, ул. Розы Люксембург, д. 15

Saransk

ФГБОУ ВО «Национальный исследовательский Мордовский государственный университет им. Н.П. Огарева»РоссияOgarev National Research Mordovian State UniversityRussian FederationГБУЗ РМ «Детская республиканская клиническая больница»РоссияChildren’s Republican Clinical Hospital,Russian Federation202313012024686112120Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20242024Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/1914

АНЦА-ассоциированный васкулит— редкое заболевание у детей, характеризующееся полиорганным поражением. Впоследние годы отмечена связь системных васкулитов, в том числе АНЦА-ассоциированных, с новой коронавирусной инфекцией. Существуют сложности в дифференциальной диагностике этих состояний. Кроме того, у пациентов с АНЦА-ассоциированным васкулитом высока частота развития венозных тромбоэмболических осложнений, что создает дополнительные сложности в диагностике и лечении этих заболеваний, особенно в детском возрасте. В статье представлен обзор данных современной литературы по проблеме и клинический случай АНЦА-ассоциированного системного васкулита с поражением почек, легких, суставов (микроскопический полиангиит) у подростка 17 лет после перенесенной коронавирусной инфекции.

ANCA-associated vasculitis is a rare disease in children characterized by multiple organ involvement. In recent years, there has been found a connection between systemic vasculitis, including ANCA-associated, and the new coronavirus infection. There are certain difficulties in the differential diagnosis of these conditions. In addition, patients with ANCA-associated vasculitis have a high incidence of venous thromboembolic complications, which creates additional difficulties in the diagnosis and treatment of this disease, especially in children. The article presents the current data review and a clinical case of ANCA-associated systemic vasculitis with damage to the kidneys, lungs, joints (microscopic polyangiitis) in a 17-year-old teenager after the coronavirus infection.

детиАНЦА-ассоциированный васкулитновая коронавирусная инфекциясистемные васкулитыchildrenANCA-associated vasculitismicroscopic polyangiitissystemic vasculitisReferencesSacri A., Chambaraud T., Ranchin B., Florkin B., Sée H., Decramer S. et al. Clinical characteristics and outcomes of childhood-onset ANCA-associated vasculitis: a French nationwide study. Eur Heart J 2015; 30: 104–112. DOI: 10.1093/ndt/gfv011Sacri A., Chambaraud T., Ranchin B., Florkin B., Sée H., Decramer S. et al. Clinical characteristics and outcomes of childhood-onset ANCA-associated vasculitis: a French nationwide study. Eur Heart J 2015; 30: 104–112. DOI: 10.1093/ndt/gfv011Jennette J.C., Falk R.J., Bacon P.A., Basu N., Cid M.C., Ferrario F. et al. 2012 revised International Chapel Hill Consensus Conference Nomenclature of vasculitides. Arthritis Rheum 2013; 65: 1–11. DOI: 10.1002/art.3771Jennette J.C., Falk R.J., Bacon P.A., Basu N., Cid M.C., Ferrario F. et al. 2012 revised International Chapel Hill Consensus Conference Nomenclature of vasculitides. Arthritis Rheum 2013; 65: 1–11. DOI: 10.1002/art.3771Литвинова М.А., Буланов Н.М., Новиков П.И., Власенко Н.В., Филатова Е.Е., Кургинян К.В. и др. Гранулематоз с полиангиитом и микроскопический полиангиит — сходства и различия. Клинческая фармакология и терапия 2023; 32(1): 64–72. DOI; 10.32756/0869–5490–2023–1–64–72Litvinova M.A., Bulanov N.M., Novikov P.I., Vlasenko N.V., Filatova E.E., Kurginyan K.V. et al. Granulomatosis with polyangiitis and microscopic polyangiitis: common features and differences. Klinicheskaya farmakologiya i terapiya 2023; 32(1): 64–72 (in Russ.) DOI; 10.32756/0869–5490–2023–1–64–72Robson J., Grayson P., Ponte C., Suppiah R., Craven A., Judge A. et al. 2022 American College of Rheumatology/ European Alliance of Associations for Rheumatology classification criteria for granulomatosis with polyangiitis. Ann Rheum Dis 2022; 81(3): 315–320. DOI: 10.1002/art.41986Robson J., Grayson P., Ponte C., Suppiah R., Craven A., Judge A. et al. 2022 American College of Rheumatology/ European Alliance of Associations for Rheumatology classification criteria for granulomatosis with polyangiitis. Ann Rheum Dis 2022; 81(3): 315–320. DOI: 10.1002/art.41986Suppiah R., Robson J., Grayson P., Ponte C., Craven A., Khalid S. et al. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for microscopic polyangiitis. Ann Rheum Dis 2022; 81(3): 321–326. DOI: 10.1136/annrheumdis-2021–221796Suppiah R., Robson J., Grayson P., Ponte C., Craven A., Khalid S. et al. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for microscopic polyangiitis. Ann Rheum Dis 2022; 81(3): 321–326. DOI: 10.1136/annrheumdis-2021–221796Jariwala M.P., Laxer M.R. Primary Vasculitis in Childhood: GPA and MPA in Childhood. Front Pediatr 2018; 6: 226. DOI: 10.3389/fped.2018.00226Jariwala M.P., Laxer M.R. Primary Vasculitis in Childhood: GPA and MPA in Childhood. Front Pediatr 2018; 6: 226. DOI: 10.3389/fped.2018.00226Бекетова Т.В. Международные рекомендации по лечению АНЦА-ассоциированных системных васкулитов. Современная ревматология 2019; 13(1): 19–25. DOI: 10.14412/1996–7012–2019–1–19–25Beketova T.V. International guidelines for the treatment of ANCA-associated systemic vasculitis. Sovremennaya revmatologiya 2019; 13(1): 19–25. (in Russ.) DOI: 10.14412/1996–7012–2019–1–19–25Misra D.P., Thomas K.N., Gasparyan A.Y., Zimba O. Mechanisms of thrombosis in ANCA-associated vasculitis. Clin Rheumatol 2021; 40(12): 4807–4815. DOI: 10.1007/s10067– 021–05790–9Misra D.P., Thomas K.N., Gasparyan A.Y., Zimba O. Mechanisms of thrombosis in ANCA-associated vasculitis. Clin Rheumatol 2021; 40(12): 4807–4815. DOI: 10.1007/s10067– 021–05790–9Hansrivijit P., Trongtorsak A., Gadhiya K.P., Lnu K., Dimech C.T., Thongprayoon C. et al. Incidence and risk factors of venous thromboembolism in ANCA-associated vasculitis: a metaanalysis and metaregression. Clin Rheumatol 2021; 40(7): 2843–2853. DOI:10.1007/s10067–021–05589–8Hansrivijit P., Trongtorsak A., Gadhiya K.P., Lnu K., Dimech C.T., Thongprayoon C. et al. Incidence and risk factors of venous thromboembolism in ANCA-associated vasculitis: a metaanalysis and metaregression. Clin Rheumatol 2021; 40(7): 2843–2853. DOI:10.1007/s10067–021–05589–8Hilhorst M., Winckers K., Wilde B., van Oerle R., ten Cate H., Tervaert J.W. Patients with antineutrophil cytoplasmic antibodies associated vasculitis in remission are hypercoagulable. J Rheumatol 2013; 40(12) :2042–2046. DOI: 10.3899/jrheum.130200Hilhorst M., Winckers K., Wilde B., van Oerle R., ten Cate H., Tervaert J.W. Patients with antineutrophil cytoplasmic antibodies associated vasculitis in remission are hypercoagulable. J Rheumatol 2013; 40(12) :2042–2046. DOI: 10.3899/jrheum.130200Liapi M., Jayne D., Merkel P.A., Segelmark M., Mohammad A.J. Venous thromboembolism in ANCA-associated vasculitis: a population-based cohort study. Rheumatology (Oxford) 2021; 60(10): 4616–4623. DOI: 10.1093/rheumatology/keab057Liapi M., Jayne D., Merkel P.A., Segelmark M., Mohammad A.J. Venous thromboembolism in ANCA-associated vasculitis: a population-based cohort study. Rheumatology (Oxford) 2021; 60(10): 4616–4623. DOI: 10.1093/rheumatology/keab057Söderberg D., Kurz T., Motamedi A., Hellmark T., Eriksson P., Segelmark M. Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission. Rheumatology (Oxford) 2015; 54: 2085–2094. DOI: 10.1093/rheumatology/kev217Söderberg D., Kurz T., Motamedi A., Hellmark T., Eriksson P., Segelmark M. Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission. Rheumatology (Oxford) 2015; 54: 2085–2094. DOI: 10.1093/rheumatology/kev217Nakazawa D., Tomaru U., Yamamoto C., Jodo S., Ishizu A. Abundant neutrophil extracellular traps in thrombus of patient with microscopic polyangiitis. Front Immunol 2012; 3: 333. DOI: 10.3389/fimmu.2012.00333Nakazawa D., Tomaru U., Yamamoto C., Jodo S., Ishizu A. Abundant neutrophil extracellular traps in thrombus of patient with microscopic polyangiitis. Front Immunol 2012; 3: 333. DOI: 10.3389/fimmu.2012.00333Zuo Y., Yalavarthi Sh., Shi H., Gockman K., Zuo M., Madison J.A. et al. Neutrophil extracellular traps in COVID-19. JCI Insight 2020; 5(11): e138999. DOI: 10.1172/jci.insight.138999Zuo Y., Yalavarthi Sh., Shi H., Gockman K., Zuo M., Madison J.A. et al. Neutrophil extracellular traps in COVID-19. JCI Insight 2020; 5(11): e138999. DOI: 10.1172/jci.insight.138999Фролова Н.Ф., Томилина Н.А., Котенко О.Н., Подкорытова О.Л., Исхаков Р.Т., Усатюк С.С. и др. Экулизумаб в лечении АНЦА-ассоциированного васкулита, осложненного Covid-19. Нефрология и диализ 2020; 22: 33–45. DOI: 10.28996/2618–9801–2020-Special_Issue-33–45Frolova N.F., Tomilina N.A., Kotenko O.N., Podkorytova O.L., Ishakov R.T., Usatyuk S.S. et al. Eculizumab in the treatment of ANCA-associated vasculitis complicated by Covid-19. Nephrologiya i dializ 2020; 22: 33–45. (in Russ.) DOI: 10.28996/2618–9801–2020-Special_Issue-33–45Hao J., Wang C., Gou S-J., Zhao M-H., Chen M. The association between anti-plasminogen antibodies and disease activity in ANCA-associated vasculitis. Rheumatology (Oxford) 2014; 53(2): 300–306. DOI: 10.1093/rheumatology/ket345Hao J., Wang C., Gou S-J., Zhao M-H., Chen M. The association between anti-plasminogen antibodies and disease activity in ANCA-associated vasculitis. Rheumatology (Oxford) 2014; 53(2): 300–306. DOI: 10.1093/rheumatology/ket345Bryant M.C., Spencer L.T., Yalcindag A. A case of ANCA-associated vasculitis in a 16-year-old female following SARS-COV-2 infection and a systematic review of the literature. Pediatr Rheumatol Online J 2022; 20(1): 65. DOI:10.1186/s12969–022–00727–1Bryant M.C., Spencer L.T., Yalcindag A. A case of ANCA-associated vasculitis in a 16-year-old female following SARS-COV-2 infection and a systematic review of the literature. Pediatr Rheumatol Online J 2022; 20(1): 65. DOI:10.1186/s12969–022–00727–1Uppal N.N., Kello N., Shah H.H., Khanin Y., De Oleo I.R., Epstein E. et al. De novo ANCA-associated vasculitis with glomerulonephritis in COVID19. Kidney Int Rep 2020; 5(11): 2079–2083. DOI: 10.1016/j.ekir.2020.08.012Uppal N.N., Kello N., Shah H.H., Khanin Y., De Oleo I.R., Epstein E. et al. De novo ANCA-associated vasculitis with glomerulonephritis in COVID19. Kidney Int Rep 2020; 5(11): 2079–2083. DOI: 10.1016/j.ekir.2020.08.012Moeinzadeh F., Dezfouli M., Naimi A., Shahidi S., Moradi H. Newly diagnosed glomerulonephritis during COVID-19 infection undergoing immunosup-pression therapy, a case report. Iran J Kidney Dis 2020; 14(3): 239–242Moeinzadeh F., Dezfouli M., Naimi A., Shahidi S., Moradi H. Newly diagnosed glomerulonephritis during COVID-19 infection undergoing immunosup-pression therapy, a case report. Iran J Kidney Dis 2020; 14(3): 239–242Jalalzadeh M., Valencia-Manrique J.C., Boma N., Chaudhari A., Chaudhari S. Antineutrophil cytoplasmic antibody-associated glomerulonephritis in a case of scleroderma after recent diagnosis with COVID-19. Cureus 2021; 13(1): e12485–e12485. DOI: 10.7759/cureus.12485Jalalzadeh M., Valencia-Manrique J.C., Boma N., Chaudhari A., Chaudhari S. Antineutrophil cytoplasmic antibody-associated glomerulonephritis in a case of scleroderma after recent diagnosis with COVID-19. Cureus 2021; 13(1): e12485–e12485. DOI: 10.7759/cureus.12485Zhou Y., Han T., Chen J., Hou C., Hua L., He S. et al. Clinical and autoimmune characteristics of severe and critical cases of COVID-19. Clin Transl Sci 2020; 13(6): 1077–1086. DOI: 10.1111/cts.12805Zhou Y., Han T., Chen J., Hou C., Hua L., He S. et al. Clinical and autoimmune characteristics of severe and critical cases of COVID-19. Clin Transl Sci 2020; 13(6): 1077–1086. DOI: 10.1111/cts.12805Shah S., Danda D., Kavadichanda C., Das S., Adarsh M.B., Negi V.S. Autoimmune and rheumatic musculoskeletal diseases as a consequence of SARS-CoV-2 infection and its treatment. Rheumatol Int 2020; 40(10): 1539–1554. DOI: 10.1007/s00296–020–04639–9Shah S., Danda D., Kavadichanda C., Das S., Adarsh M.B., Negi V.S. Autoimmune and rheumatic musculoskeletal diseases as a consequence of SARS-CoV-2 infection and its treatment. Rheumatol Int 2020; 40(10): 1539–1554. DOI: 10.1007/s00296–020–04639–9Izci Duran T., Turkmen E., Dilek M., Sayarlioglu H., Arik N. ANCA-associated vasculitis after COVID-19. Rheumatol Int 2021; 41(8): 1523–1529. DOI:10.1007/s00296–021– 04914–3 24. Ozcan S., Sonmez O., Karaca C., Ozdede A., Seyahi N. ANCA-associated vasculitis flare might be provoked by COVID-19 infection: a case report and a review of the literature. Clin Kidney J 2022; 15(11): 1987–1995. DOI: 10.1093/ckj/sfac186Izci Duran T., Turkmen E., Dilek M., Sayarlioglu H., Arik N. ANCA-associated vasculitis after COVID-19. Rheumatol Int 2021; 41(8): 1523–1529. DOI:10.1007/s00296–021– 04914–3 24. Ozcan S., Sonmez O., Karaca C., Ozdede A., Seyahi N. ANCA-associated vasculitis flare might be provoked by COVID-19 infection: a case report and a review of the literature. Clin Kidney J 2022; 15(11): 1987–1995. DOI: 10.1093/ ckj/sfac186Hashizume H., Sano Y., Furukawa S., Imokawa S. Eosinophilic granulomatosis with polyangiitis mimicking coronavirus disease 2019: a case report. J Eur Acad Dermatol Venereol 2020; 34(10): e557–e559. DOI: 10.1111/jdv.16705Hashizume H., Sano Y., Furukawa S., Imokawa S. Eosinophilic granulomatosis with polyangiitis mimicking coronavirus disease 2019: a case report. J Eur Acad Dermatol Venereol 2020; 34(10): e557–e559. DOI: 10.1111/jdv.16705Qurratulain Q., Ahmed A., Jones Q. Lesson of the month: severe granu-lomatosis with polyangiitis (GPA): a diagnostic challenge during the COVID-19 pandemic. Clin Med (Lond) 2021; 21(1): 79–80. DOI: 10.7861/clinmed.2020–0793Qurratulain Q., Ahmed A., Jones Q. Lesson of the month: severe granu-lomatosis with polyangiitis (GPA): a diagnostic challenge during the COVID-19 pandemic. Clin Med (Lond) 2021; 21(1): 79–80. DOI: 10.7861/clinmed.2020–0793Becker R.C. COVID-19-associated vasculitis and vasculopathy. J Thromb Thrombolysis 2020; 50(3): 499–511. DOI: 10.1007/s11239–020–02230–4Becker R.C. COVID-19-associated vasculitis and vasculopathy. J Thromb Thrombolysis 2020; 50(3): 499–511. DOI: 10.1007/s11239–020–02230–4Chamorro M.E., Tascón D.A., Sanz I.L., Vélez O.S., Nacenta B.S. Radiologic diagnosis of patients with COVID-19. Radiologia 2021; 63(1): 56–73. DOI: 10.1016/j.rx.2020.11.001Chamorro M.E., Tascón D.A., Sanz I.L., Vélez O.S., Nacenta B.S. Radiologic diagnosis of patients with COVID-19. Radiologia 2021; 63(1): 56–73. DOI: 10.1016/j.rx.2020.11.001Eslambolchi A., Aghaghazvini L., Gholamrezanezhad A., Kavosi H., Radmard A.R. Coronavirus disease 2019 (COVID-19) in patients with systemic au-toimmune diseases or vasculitis: radiologic presentation. J Thromb Thrombolysis 2021; 51(2): 339–348. DOI: 10.1007/s11239–020–02289-zEslambolchi A., Aghaghazvini L., Gholamrezanezhad A., Kavosi H., Radmard A.R. Coronavirus disease 2019 (COVID-19) in patients with systemic au-toimmune diseases or vasculitis: radiologic presentation. J Thromb Thrombolysis 2021; 51(2): 339–348. DOI: 10.1007/s11239–020–02289-zChan L., Chaudhary K., Saha A., Chauhan K., Vaid A., Zhao S. et al. AKI in hospitalized patients with COVID-19. J Am Soc Nephrol 2021; 32(1): 151–160. DOI: 10.1681/ASN.2020050615Chan L., Chaudhary K., Saha A., Chauhan K., Vaid A., Zhao S. et al. AKI in hospitalized patients with COVID-19. J Am Soc Nephrol 2021; 32(1): 151–160. DOI: 10.1681/ASN.2020050615Geetha D., Jeferson J.A. ANCA-associated vasculitis: core curriculum 2020. Am J Kidney Dis 2020; 75(1): 124–137. DOI: 10.1053/j.ajkd.2019.04.031Geetha D., Jeferson J.A. ANCA-associated vasculitis: core curriculum 2020. Am J Kidney Dis 2020; 75(1): 124–137. DOI: 10.1053/j.ajkd.2019.04.031Kraaij T., Kamerling W.A., van Dam S., Bakker A., Bajema M., Page T., Brunini F. et al. Excessive neutrophil extracellular trap formation in ANCA-associated vasculitis is independent of ANCA. Kidney Int 2018; 94: 139–149. DOI: 10.1016/j.kint.2018.01.013Kraaij T., Kamerling W.A., van Dam S., Bakker A., Bajema M., Page T., Brunini F. et al. Excessive neutrophil extracellular trap formation in ANCA-associated vasculitis is independent of ANCA. Kidney Int 2018; 94: 139–149. DOI: 10.1016/j.kint.2018.01.013Söderberg D., Segelmark M. Neutrophil extracellular traps in ANCA-associated vasculitis. Front Immunol 2016; 7: 256– 256. DOI: 10.3389/fimmu.2016.00256Söderberg D., Segelmark M. Neutrophil extracellular traps in ANCA-associated vasculitis. Front Immunol 2016; 7: 256– 256. DOI: 10.3389/fimmu.2016.00256Batu E.D., Sener S., Ozen S. COVID-19 associated pediatric vasculitis: A systematic review and detailed analysis of the pathogenesis. Semin Arthritis Rheum 2022; 55: 152047. DOI: 10.1016/j.semarthrit.2022.152047Batu E.D., Sener S., Ozen S. COVID-19 associated pediatric vasculitis: A systematic review and detailed analysis of the pathogenesis. Semin Arthritis Rheum 2022; 55: 152047. DOI: 10.1016/j.semarthrit.2022.152047Reiff D.D., Meyer C.G., Marlin B., Mannion M.L. New onset ANCA-associated vasculitis in an adolescent during an acute COVID-19 infection: a case report. BMC Pediatr 2021; 21(1): 333. DOI: 10.1186/s12887–021–02812-yReiff D.D., Meyer C.G., Marlin B., Mannion M.L. New onset ANCA-associated vasculitis in an adolescent during an acute COVID-19 infection: a case report. BMC Pediatr 2021; 21(1): 333. DOI: 10.1186/s12887–021–02812-yFireizen Y., Shahriary C., Imperial M.E., Randhawa I., Nianiaris N., Ovunc B. Pediatric P-ANCA vasculitis following COVID-19. Pediatr Pulmonol 2021; 56(10): 3422–3424. DOI: 10.1002/ppul.25612Fireizen Y., Shahriary C., Imperial M.E., Randhawa I., Nianiaris N., Ovunc B. Pediatric P-ANCA vasculitis following COVID-19. Pediatr Pulmonol 2021; 56(10): 3422–3424. DOI: 10.1002/ppul.25612Raeeskarami S.R., Mousavi S.H., Ashouri M., Akbariasbagh P., Assari R., Naderi S. Could COVID-19 Trigger Presentation or Exacerbation of Vasculitides? (A 14-Year-Old Girl with Newly Diagnosed GPA After COVID-19 Infection) Iran J Pediatr 2021; 31(3): 1–7. DOI: 10.5812/ijp.110597Raeeskarami S.R., Mousavi S.H., Ashouri M., Akbariasbagh P., Assari R., Naderi S. Could COVID-19 Trigger Presentation or Exacerbation of Vasculitides? (A 14-Year-Old Girl with Newly Diagnosed GPA After COVID-19 Infection) Iran J Pediatr 2021; 31(3): 1–7. DOI: 10.5812/ijp.110597Powell W.T., Campbell J.A., Ross F., Pena Jimenez P., Rudzinski E.R., Dickerson J.A. Acute ANCA Vasculitis and Asymptomatic COVID 19. Pediatrics 2021; 147(4): e2020033092. DOI: 10.1542/peds.2020–033092Powell W.T., Campbell J.A., Ross F., Pena Jimenez P., Rudzinski E.R., Dickerson J.A. Acute ANCA Vasculitis and Asymptomatic COVID 19. Pediatrics 2021; 147(4): e2020033092. DOI: 10.1542/peds.2020–033092Wintler T., Zherebtsov M., Carmack S., Muntean R., Hill S.J. Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager. J Pediatr Surg Case Rep 2021; 75: 102103. DOI: 10.1016/j.epsc.2021.102103Wintler T., Zherebtsov M., Carmack S., Muntean R., Hill S.J. Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager. J Pediatr Surg Case Rep 2021; 75: 102103. DOI: 10.1016/j.epsc.2021.102103Bryant M.C., Spencer L.T., Yalcindag A. A case of ANCA-associated vasculitis in a 16-year-old female following SARS-COVID-2 infection and a systematic review of the literature. Pediatr Rheumatol Online J 2022; 20(1): 65. DOI: 10.1186/s12969–022–00727–1Bryant M.C., Spencer L.T., Yalcindag A. A case of ANCA-associated vasculitis in a 16-year-old female following SARS-COVID-2 infection and a systematic review of the literature. Pediatr Rheumatol Online J 2022; 20(1): 65. DOI: 10.1186/s12969–022–00727–1Савенкова Н.Д. ANCA-ассоциированные васкулиты у детей. Нефрология 2014; 18(3): 16–23.Савенкова Н.Д. ANCA-ассоциированные васкулиты у детей. Нефрология 2014; 18(3): 16–23. [Savenkova N.D. ANCA-associated vasculitis in children. Nefrologiya 2014; 18(3): 16–23. (in Russ.)]Sun L., Wang H., Jiang X., Mo Y., Yue Z., Huang L., Liu T. Clinical and pathological features of microscopic polyangiitis in 20 children. J Rheumatol 2014; 41(8): 1712–1719. DOI: 10.3899/jrheum.131300Sun L., Wang H., Jiang X., Mo Y., Yue Z., Huang L., Liu T. Clinical and pathological features of microscopic polyangiitis in 20 children. J Rheumatol 2014; 41(8): 1712–1719. DOI: 10.3899/jrheum.131300Ames P.R., Margaglione M., Mackie S., Alves J.D. Eosinophilia and thrombophilia in churg strauss syndrome: a clinical and pathogenetic overview. Clin Appl Thromb Hemost 2010; 16(6): 628–636. DOI: 10.1177/107602960934864Ames P.R., Margaglione M., Mackie S., Alves J.D. Eosinophilia and thrombophilia in churg strauss syndrome: a clinical and pathogenetic overview. Clin Appl Thromb Hemost 2010; 16(6): 628–636. DOI: 10.1177/107602960934864Kronbichler A., Leierer J., Gauckler P., Shin J.I. Comorbidities in ANCA-associated vasculitis. Rheumatology (Oxford) 2020; 59(3): 79–83. DOI: 10.1093/rheumatology/kez617Kronbichler A., Leierer J., Gauckler P., Shin J.I. Comorbidities in ANCA-associated vasculitis. Rheumatology (Oxford) 2020; 59(3): 79–83. DOI: 10.1093/rheumatology/kez617Методические рекомендации «Особенности клинических проявлений и лечения заболевания, вызванного новой коронавирусной инфекцией (COVID-19) у детей. Версия 2» (03.07.2020). Министерство здравоохранения Российской Федерации. Доступно на: https://static-0.minzdrav.gov.ru/system/attachments/attaches/000/050/914/original/03062020_дети_COVID-19_v2.pdf46Metodicheskie rekomendatsii «Osobennosti klinicheskikh proyavlenii i lecheniia zabolevaniia, vyzvannogo novoi koronavirusnoi infektsiei (COVID-19) u detei. Versiya 2» (03.07.2020). Ministerstvo zdravookhraneniya Rossiiskoi Federatsii. Dostupno na: https://static-0.minzdrav.gov.ru/system/attachments/attaches/000/050/914/original/03062020_deti_COVID-19_v2.pdf46 (in Russ.)Мазанкова Л.Н., Самитова Э.Р., Османов И.М., Афуков И.И., Драчева Н.А. и др. Клинико-эпидемиологические особенности течения новой коронавирусной инфекции COVID-19 у детей в периоды подъема заболеваемости в городе Москве в 2020–2021 гг. Детские инфекции 2021; 20(3): 5–10. DOI: 10.22627/2072–8107–2021–20–3–5–10Mazankova L.N., Samitova E.R., Osmanov I.M., Afukov I.I., Drachev N.A. et al. Clinical and epidemiological features of the course of a new coronavirus infection COVID-19 in children during periods of rising incidence in the city of Moscow in 2020–2021. Detskie infektsii 2021; 20(3): 5–10. (in Russ.) DOI: 10.22627/2072–8107–2021–20–3–5–10Бурлуцкая А.В., Савельева Н.В., Таран Н.С. ANCA-ассоциированный васкулит у подростка 14 лет: клинический случай. Кубанский научный медицинский вестник 2020; 27(5): 184–194. DOI: 10.25207/1608-6228-2020-27-5-184-194Burluzkaya A.V., Savel'yeva N.V., Taran N.S. ANCA-associated vasculitis in a 14-year-old ado-lescent: a clinical case. Kubanskyi nauchnyi medizinskyi vestnik 2020; 27(5): 184–194. (In Russ.) DOI: 10.25207/1608-6228-2020-27-5-184-194

The authors declare that there are no conflicts of interest present.