perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”perinatology-198Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWSПоследствия гестоза (преэклампсии)Consequences of gestosis (preeclampsia)ПерфиловаВ. Н.PerfilovaV. N.

д.б.н., стн.с. лаборатории фармакологии сердечно-сосудистых средств НИИ фармакологии Волгоградского государственного медицинского университета

МихайловаЛ. И.MikhailovaL. I.

асп. той же каф

ТюренковИ. Н.TyurenkovI. N.

член-корр. РАМН, проф., д.м.н., зав. каф. фармакологии и биофармации Волгоградского государственного медицинского университета

Волгоградский государственный медицинский университетРоссияVolgograd State Medical UniversityRussian Federation2014150320165921318Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20162016Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/198

В обзоре представлены результаты анализа данных отечественной и зарубежной литературы, которые показывают, что тяжелый гестоз (преэклампсия) является одной из основных причин перинатальной заболеваемости и смертности. Тяжелый гестоз ведет к нарушению роста и развития плода, рождению недоношенных детей, формированию перинатальных поражений гипоксического характера центральной нервной, сердечно-сосудистой, эндокринной, иммунной, дыхательной и других систем, что негативно влияет на состояние здоровья детей в последующие годы жизни. У женщин с пре- или эклампсией в анамнезе в последующем имеется повышенный риск развития сердечно-сосудистых (атеросклероза, ишемической болезни сердца, заболеваний периферических артерий, артериальной гипертонии), цереброваскулярных заболеваний, патологии почек и органов зрения, сахарного диабета, нарушения памяти.

The review presents the results of an analysis of the data available in the Russian and foreign literature, which show that severe gestosis (preeclampsia) is a main cause of perinatal morbidity and mortality. Severe gestosis leads to impaired fetal growth and development, premature births, the development of perinatal hypoxic lesions of the central nervous, cardiovascular, endocrine, immune, respiratory, and other systems, which adversely affects the health status of children in their later life. Women with a history of preeclampsia or eclampsia are further at increased risk for cardiovascular (atherosclerosis, coronary heart disease, peripheral arterial diseases, and hypertension), cerebrovascular diseases, abnormalities of the kidney and organs of vision, diabetes, and memory impairments.

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The authors declare that there are no conflicts of interest present.