perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”perinatology-215Research ArticleОБМЕН ОПЫТОМSHARING EXPERIENCESПилотное исследование использования продуктов класса ОРГАНИК в питании детей с атопическим дерматитомPilot study of the use of ORGANIC food products in the diet of infants with atopic dermatitisКазначеевК. С.KaznacheevK. S.

к.м.н., доц. кафедры педиатрии и неонатологии

КазначееваЛ. Ф.KaznacheevaL. F.

д.м.н., проф. кафедры педиатрии и неонатологии

СкиданИ. Н.SkidanI. N.

к.м.н., рук. научного отдела

ВолоховаК. С.VolokhovaK. S.

врач педиатр

ЧегановаЮ. В.CheganovaYu. V.

врач-диетолог

ДубровинаЛ. Н.DubrovinaL. N.

зам. гл. врача по лечебной работе

КоноваловаО. Н.KonovalovaO. N.

зав. педиатрическим отделением поликлинического отделения

ГБОУ ВПО «Новосибирский государственный медицинский университет»РоссияNovosibirsk State Medical University, NovosibirskRussian FederationКомпания «Бибиколь-РУС», МытищиРоссияBibicall-RUS Ltd., Mytishchi, Moscow RegionRussian FederationООО «Центр семейной реабилитации»РоссияООО «Центр семейной реабилитации»Russian FederationКГБУЗ «Дом ребенка специализированный», БарнаулРоссияSpecialized Children’s Home, BarnaulRussian FederationГБУЗ НСО «Детская городская клиническая больница №1», НовосибирскРоссияCity Children’s Clinical Hospital One, NovosibirskRussian Federation20151503201660398103Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20162016Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/215

В последние десятилетия появляются публикации, свидетельствующие о положительном влиянии продуктов органического сельского хозяйства на здоровье детей, в том числе страдающих аллергией. В статье представлены результаты оценки переносимости органических плодоовощных пюре БИБИКОЛЬ у детей первого года жизни, страдающих атопическим дерматитом. Проведено пилотное открытое неконтролируемое исследование, в которое включено 80 здоровых доношенных детей в возрасте от 5 до 10 мес жизни с наличием атопического дерматита, находившихся как на грудном, так и на искусственном вскармливании. Жесткий контроль рациона осуществлялся у 22 детей. В ходе введения прикорма у 78 пациентов не отмечалось обострения заболевания за весь период наблюдения. Сделано заключение, что в период ремиссии атопического дерматита, при отсутствии сенсибилизации, функциональных нарушений со стороны желудочно-кишечного тракта возможно введение в рацион детей органических продуктов питания даже с высокой сенсибилизирующей активностью (таких как пюре из моркови). Показано достоверное благотворное регулирующее влияние введения овощных и фруктовых пюре ОРГАНИК на функцию желудочно-кишечного тракта, проявляющееся нормализацией моторных нарушений (в том числе колик – χ2=20,31; p<0,05, срыгивания – χ2=18,37; p<0,01), метеоризма (χ2=4,99; p<0,05) и адекватным перевариванием. 

In the past decades, there have been publications suggesting the positive effect of organic farming food products on the health of children, including allergic persons. The paper presents the results of assessing the tolerance of BIBICALL organic fruit-and-vegetable purées in atopic dermatitis infants of the first year of life. A pilot open-label uncontrolled trial was conducted in 80 healthy full-term babies aged 5 tо 10 months with atopic dermatitis who were breast or formula fed; their diet was tightly controlled in 22 infants. When additional foods were given, 78 patients were observed to have no exacerbation throughout the follow-up. It is concluded that organic food products even with high sensitizing activity (such as carrot purée) may be added to the diet of babies with atopic dermatitis remission in the absence of sensitization, gastrointestinal tract dysfunction. Addition of ORGANIC vegetable and fruit purées was shown to have a significant favorable regulatory impact on gastrointestinal function, which showed as normalization of motor disorders (including colic χ2=20,31; p<0,05, regurgitation χ2=18,37; p<0,01), tympanism (χ2=4,99; p<0,05), and adequate digestion. 

детиатопический дерматитфункциональные нарушения желудочно-кишечного трактаприкормпродукты органикbabiesatopic dermatitisgastrointestinal tract dysfunctionadditional foodsorganic food productsReferencesEuropean Council. Council Regulation (EEC) No 2092/91 of 4 June 1991 on organic production of agricultural products and indications referring thereto on agricultural products and oodstuffs. 2005; https://www.fsai.ie/uploadedFiles/Legislation/ Food_Legisation_Links/Organic_foodstuffs/Consol_ Reg2092_91.pdfEuropean Council. Council Regulation (EEC) No 2092/91 of 4 June 1991 on organic production of agricultural products and indications referring thereto on agricultural products and oodstuffs. 2005; https://www.fsai.ie/uploadedFiles/Legislation/ Food_Legisation_Links/Organic_foodstuffs/Consol_ Reg2092_91.pdfSmit L.A., Zuurbier M., Doekes G. et al. Hay fever and asthma symptoms in conventional and organic farmers in The Netherlands. Occup Environ Med 2007; 64: 2: 101–107.Smit L.A., Zuurbier M., Doekes G. et al. Hay fever and asthma symptoms in conventional and organic farmers in The Netherlands. Occup Environ Med 2007; 64: 2: 101–107.Lesueur C., Gartner M., Knittl P. et al. Pesticide residues in fruit and vegetable samples: analytical results of 2 year s pesticide investigations. Ernährung/Nutrition 2007; 31: 6: 247–259.Lesueur C., Gartner M., Knittl P. et al. Pesticide residues in fruit and vegetable samples: analytical results of 2 year s pesticide investigations. Ernährung/Nutrition 2007; 31: 6: 247–259.Tasiopoulou S., Chiodini A.M., Vellere F. et al. Results of the monitoring program of pesticide residues in organic food of plant origin in Lombardy (Italy). J Environ Sci Health B 2007; 42: 7: 835–841.Tasiopoulou S., Chiodini A.M., Vellere F. et al. Results of the monitoring program of pesticide residues in organic food of plant origin in Lombardy (Italy). J Environ Sci Health B 2007; 42: 7: 835–841.Han F., Lestari S.I., Pu S., Ge B. Prevalence and antimicrobial resistance among Campylobacter spp. in Louisiana retail chickens after the enrofloxacin ban. Foodborne Pathog Dis 2009; 6: 2: 163–171.Han F., Lestari S.I., Pu S., Ge B. Prevalence and antimicrobial resistance among Campylobacter spp. in Louisiana retail chickens after the enrofloxacin ban. Foodborne Pathog Dis 2009; 6: 2: 163–171.Garmo R.T, Waage S., Sviland S. et al. Reproductive Performance, Udder Health, and Antibiotic Resistance in Mastitis Bacteria isolated from Norwegian Red cows in Conventional and Organic Farming. Acta Veter Scand 2010; 52: 11–24.Garmo R.T, Waage S., Sviland S. et al. Reproductive Performance, Udder Health, and Antibiotic Resistance in Mastitis Bacteria isolated from Norwegian Red cows in Conventional and Organic Farming. Acta Veter Scand 2010; 52: 11–24.Schmied E.M., Bauer J. Comparative analysis of antibiotic resistance characteristics of Gram-negative bacteria isolated from laying hens and eggs in conventional and organic keeping systems in Bavaria, Germany. Zoonoses Public Health 2008; 55: 7: 331–341.Schmied E.M., Bauer J. Comparative analysis of antibiotic resistance characteristics of Gram-negative bacteria isolated from laying hens and eggs in conventional and organic keeping systems in Bavaria, Germany. Zoonoses Public Health 2008; 55: 7: 331–341.Miranda J.M., Vázquez B.I., Fente C.A. et al. Comparison of antimicrobial resistance in Escherichia coli, Staphylococcus aureus, and Listeria monocytogenes strains isolated from organic and conventional poultry meat. J Food Protect 2008; 71: 12: 2537–2542.Miranda J.M., Vázquez B.I., Fente C.A. et al. Comparison of antimicrobial resistance in Escherichia coli, Staphylococcus aureus, and Listeria monocytogenes strains isolated from organic and conventional poultry meat. J Food Protect 2008; 71: 12: 2537–2542.Cui S., Ge B., Zheng J., Meng J. Prevalence and Antimicrobial Resistance of Campylobacter spp. and Salmonella Serovars in Organic Chickens from Maryland Retail Stores. Appl Environ Microbiol 2005; 71: 4108–4111.Cui S., Ge B., Zheng J., Meng J. Prevalence and Antimicrobial Resistance of Campylobacter spp. and Salmonella Serovars in Organic Chickens from Maryland Retail Stores. Appl Environ Microbiol 2005; 71: 4108–4111.Lestari S.I., Han F., Wang F., Ge B. Prevalence and antimicrobial resistance of Salmonella serovars in conventional and organic chickens from Louisiana retail stores. J Food Protect 2009; 72: 6: 1165–1172.Lestari S.I., Han F., Wang F., Ge B. Prevalence and antimicrobial resistance of Salmonella serovars in conventional and organic chickens from Louisiana retail stores. J Food Protect 2009; 72: 6: 1165–1172.Oliveira A.B., Moura C.F.H., Gomes-Filho E. et al. The Impact of organic farming on quality of tomatoes is associated to increased oxidative stress during fruit development. PLoS ONE 2013; 8: 2: e56354.Oliveira A.B., Moura C.F.H., Gomes-Filho E. et al. The Impact of organic farming on quality of tomatoes is associated to increased oxidative stress during fruit development. PLoS ONE 2013; 8: 2: e56354.Benbrook C.M., Butler G., Latif M.A. et al. Organic Production Enhances Milk Nutritional Quality by Shifting Fatty Acid Composition: A United States–Wide, 18-Month Study. PLoS ONE 2013; 8: 12: e82429.Benbrook C.M., Butler G., Latif M.A. et al. Organic Production Enhances Milk Nutritional Quality by Shifting Fatty Acid Composition: A United States–Wide, 18-Month Study. PLoS ONE 2013; 8: 12: e82429.Palupi E., Jayanegara A., Ploeger A. et al. Comparison of nutritional quality between conventional and organic dairy products: a meta-analysis. J Sci Food Agric 2012; 92: 2774–2781.Palupi E., Jayanegara A., Ploeger A. et al. Comparison of nutritional quality between conventional and organic dairy products: a meta-analysis. J Sci Food Agric 2012; 92: 2774–2781.Kummelinga I., Thijsa C., Huber M. et al. Consumption of organic foods and risk of atopic disease during the first 2 years of life in the Netherlands Br J Nutr 2008; 99: 3: 598–605.Kummelinga I., Thijsa C., Huber M. et al. Consumption of organic foods and risk of atopic disease during the first 2 years of life in the Netherlands Br J Nutr 2008; 99: 3: 598–605.Randhawa S., Bahna S.L. Hypersensitivity reactions to food additives. Curr Opin Allergy Clin Immunol 2009; 9: 3: 278– 283.Randhawa S., Bahna S.L. Hypersensitivity reactions to food additives. Curr Opin Allergy Clin Immunol 2009; 9: 3: 278– 283.Huen K., Harley K., Brooks J. et al. Developmental Changes in PON1 Enzyme Activity in Young Children and Effects of PON1 Polymorphisms Environ Health Perspect 2009; 117: 1632–1638.Huen K., Harley K., Brooks J. et al. Developmental Changes in PON1 Enzyme Activity in Young Children and Effects of PON1 Polymorphisms Environ Health Perspect 2009; 117: 1632–1638.

The authors declare that there are no conflicts of interest present.