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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">perinatology</journal-id><journal-title-group><journal-title xml:lang="ru">Российский вестник перинатологии и педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1027-4065</issn><issn pub-type="epub">2500-2228</issn><publisher><publisher-name>Ltd. “The National Academy of Pediatric Science and Innovation”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21508/1027-4065-2025-70-5-14-20</article-id><article-id custom-type="elpub" pub-id-type="custom">perinatology-2270</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEWS</subject></subj-group></article-categories><title-group><article-title>Геморрагическая лихорадка с почечным синдромом у детей</article-title><trans-title-group xml:lang="en"><trans-title>Hemorrhagic fever with renal syndrome in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6167-1882</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Булатова</surname><given-names>А. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Bulatova</surname><given-names>A. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Булатова Асия Халитовна — к.м.н., ассистент кафедры инфекционных болезней.</p><p>420012, Казань, ул. Бутлерова, д. 49</p></bio><bio xml:lang="en"><p>420012, Kazan</p></bio><email xlink:type="simple">asiyakhaertynova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1174-8279</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шакирова</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Shakirova</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шакирова Венера Гусмановна — д.м.н., доцент кафедры инфекционных болезней.</p><p>420012, Казань, ул. Бутлерова, д. 36</p></bio><bio xml:lang="en"><p>420012, Kazan</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Казанский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Казанская государственная медицинская академия, филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical Academy, Branch Campus of the Medical Academy of Continuous Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>14</day><month>11</month><year>2025</year></pub-date><volume>70</volume><issue>5</issue><fpage>14</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ltd. “The National Academy of Pediatric Science and Innovation”, 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><copyright-holder xml:lang="en">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><license xlink:href="https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://www.ped-perinatology.ru/jour/article/view/2270">https://www.ped-perinatology.ru/jour/article/view/2270</self-uri><abstract><p>Геморрагическая лихорадка с почечным синдромом — наиболее распространенная природно-очаговая инфекция в Поволжском Федеральном округе. Частота развития геморрагической лихорадки с почечным синдромом у детей колеблется от 2 до 10%. По мнению большинства авторов, данное заболевание у детей характеризуется развитием более легких форм заболевания по сравнению со взрослыми. В ряде случаев у детей геморрагическая лихорадка с почечным синдромом может протекать без острого почечного повреждения. Развитие тяжелых форм заболевания ассоциируется с особенностями возбудителя и выраженностью иммунного ответа. Для диагностики геморрагической лихорадки с почечным синдромом традиционно применяются серологические методы обследования, на ранних сроках диагностическую ценность представляет проведение полимеразной цепной реакции. Характерным признаком заболевания при проведении ультразвукового исследования является симптом «выделяющихся пирамидок».</p></abstract><trans-abstract xml:lang="en"><p>Hemorrhagic fever with renal syndrome is the most prevalent natural focal infection in the Volga Federal District. The incidence of hemorrhagic fever with renal syndrome in children ranges from 2–10%. According to most researchers, this disease in children typically follows a milder course compared to adults. In some pediatric cases, hemorrhagic fever with renal syndrome may present without acute kidney injury. Severe forms of the disease are associated with pathogen-specific factors and the intensity of the immune response. For diagnosis of the syndrome, serological testing remains the standard approach, while polymerase chain reaction may be utilized in early stages. A characteristic ultrasonographic finding in hemorrhagic fever with renal syndrome is the “prominent pyramids sign”.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>геморрагическая лихорадка с почечным синдромом</kwd><kwd>острое почечное повреждение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>hemorrhagic fever with renal syndrome</kwd><kwd>acute kidney injury</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Иванис В.А., Попов А.Ф., Томилка Г.С., Фигурнов В.А. Геморрагическая лихорадка с почечным синдромом — проблема здравоохранения настоящего времени. Тихоокеанский медицинский журнал 2015; 1 (59): 21–25.</mixed-citation><mixed-citation xml:lang="en">Ivanis V.A., Popov A.F., Tomilka G.S., Figurnov V.A. Hemorrhagic fever with renal syndrome — the health problem of the present time. 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