References

perinatology

Российский вестник перинатологии и педиатрии

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)

1027-40652500-2228

Ltd. “The National Academy of Pediatric Science and Innovation”

10.21508/1027-4065-2026-71-1-7-15

perinatology-2352

Research Article

ОБЗОРЫ ЛИТЕРАТУРЫ

LITERATURE REVIEWS

Полная атриовентрикулярная блокада с удлинением интервала QT

Complete atrioventricular block with prolonged QT interval

https://orcid.org/0000-0001-6028-1156

Полякова

Е. Б.

Polyakova

E. B.

Полякова Екатерина Борисовна - к.м.н., с.н.с. отдела детской кардиологии и аритмологии

125412, Москва

125412, Moscow

e_polyakova75@mail.ru

https://orcid.org/0009-0009-7696-9794

Мирошникова

Е. Н.

Miroshnikova

E. N.

Мирошникова Екатерина Николаевна-врач функциональной диагностики

125412, г. Москва, ул. Талдомская, дом 2

125412, Moscow

ОСП Научно-исследовательский клинический институт педиатрии и детской хирургии имени академика Ю.Е. Вельтищева ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава РоссииРоссияVeltischev Research and Clinical Institute for pediatrics and pediatric surgery at the Pirogov Russian National Research Medical UniversityRussian Federation

2026

20042026

711715

2026

Ltd. “The National Academy of Pediatric Science and Innovation”

https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice

https://www.ped-perinatology.ru/jour/article/view/2352

Внезапная сердечная смерть является крайне актуальной проблемой и занимает около 50% среди смертей от сердечно-сосудистых заболеваний. В обзоре представлена информация об известных механизмах удлинения интервала QT у пациентов с полной атриовентрикулярной блокадой. Представлены подтверждения значимости изменений процессов реполяризации для развития жизнеугрожающих желудочковых тахиаритмий при полной атриовентрикулярной блокаде, в том числе у детей. Многообразие механизмов, влияющих на реполяризацию миокарда у пациентов с полной атриовентрикулярной блокадой, значительно утяжеляет течение и прогноз заболевания, затрудняет подходы к лечению пациентов, особенно в раннем возрасте. Определение предиктивных значений параметров реполяризации у детей крайне важно для профилактики развития аритмогенных синкопальных состояний и внезапной сердечной смерти.

Sudden cardiac death is a serious problem that accounts for approximately 50% of deaths due to cardiovascular diseases. This review provides information about the known mechanisms that prolong the QT interval in patients with complete atrioventricular block. It also presents evidence of the significance of changes in repolarization processes for the development of life-threatening ventricular tachyarrhythmias, including in children. The variety of factors affecting myocardial repolarization in patients with complete atrioventricular block significantly worsens the course of the disease and prognosis and complicates approaches to the treatment of patients, especially in young children. It is important to determine predictive values of repolarization parameters in children for the prevention of the development of arrhythmogenic syncope and sudden cardiac death.

детивнезапная сердечная смертьполная атриовентрикулярная блокадаудлинение интервала QTжелудочковая тахикардия типа «пируэт»

childrensudden cardiac deathcomplete atrioventricular blocklong QTventricular tachycardia torsades de pointes

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The authors declare that there are no conflicts of interest present.