perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”perinatology-274Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWSПоражение сердца и коронарных артерий при синдроме КавасакиHeart and coronary artery damage related to Kawasaki syndromeЛеонтьеваА. А.LeontyevaA. A.

врач ультразвуковой диагностики отделения ультразвуковой диагностики Университетской детской клинической больницы Первого Московского государственного медицинского университета им. И.М.Сеченова

ШиринскаяО. Г.ShirinskayaO. G.

к.м.н., врач ультразвуковой диагностики того же отделения

ЛыскинаГ. А.LyskinaG. A.

д.м.н., проф. каф. детских болезней той же больницы

ПодчерняеваН. С.PodchemyaevaN. S.

д.м.н., проф. той же каф. 119435 Москва, ул. Большая Пироговская, д. 19

Первый Московский государственный медицинский университет им. И.М. СеченоваРоссияI.M. Sechenov First Moscow State Medical UniversityRussian Federation2014170320165962531Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20162016Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/274

Синдром Кавасаки — острый системный васкулит неизвестной этиологии, которым болеют преимущественно дети первых 5 лет жизни. В настоящее время синдром Кавасаки признан ведущей причиной приобретенных органических заболеваний сердца у детей, которые могут приводить к ишемической болезни сердца, инфаркту миокарда и внезапной смерти у детей и лиц молодого возраста. Большинство осложнений связаны с сердечно-сосудистой системой, особенно с изменениями коронарных артерий. Основным методом исследования при синдроме Кавасаки является трансторакальная эхокардиография, которая, помимо оценки коронарных артерий, позволяет оценить систолическую и диастолическую функции правого и левого желудочков, изучить состояние клапанов сердца, динамику перикардиального выпота. В статье изложены современные данные об эпидемиологии, этиологии, патогенетических механизмах и патоморфологии синдрома Кавасаки. Рассмотрены возможные коронарные и некоронарные изменения, исходы и клинические проявления.

Kawasaki syndrome is an acute systemic vasculitis of unknown etiology, which mainly affects children within the first 5 years of fife. At the present time, Kawasaki syndrome is recognized to be a leading cause of acquired organic heart diseases in children, which may result in coronary heart disease, myocardial infarction, and sudden death in children and young people. Most complications are associated with the cardiovascular system, with coronary artery changes in particular. Transthoracic echocardiography, which, besides coronary artery assessment, makes it possible to evaluate right and left ventricular systolic and diastolic functions and to study the cardiac valves and changes in pericardial effusion, is a major technique in Kawasaki syndrome. The paper outlines an update on the epidemiology, etiology, pathogenetic mechanisms, and pathomorphology of Kawasaki syndrome and considers possible coronary and noncoronary changes, outcomes, and clinical manifestations.

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The authors declare that there are no conflicts of interest present.