perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2014-59-6-7-8perinatology-275Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWSКлинические особенности синдрома Кавасаки у детей, заболевших в возрасте до 6 месяцевClinical features of Kawasaki syndrome in infants less than 6 months of ageЛыскинаГ. А.LyskinaG. A.

д.м.н., проф. каф. детских болезней лечебного факультета Первого московского государственного медицинского университета им. И.М. Сеченова

ТорбякА. В.TorbyakA. V.

асп. каф., врач-кардиолог окружного консультативно-диагностического центра 119981 Москва, ул. Большая Пироговская, д. 19, стр. 1

Первый Московский государственный медицинский университет им. И.М. СеченоваРоссияI.M. Sechenov First Moscow State Medical UniversityRussian Federation2014170320165963239Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20162016Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/275

Синдром Кавасаки — остро протекающее системное заболевание. Клинически характеризуется лихорадкой, изменениями слизистых оболочек, кожи, лимфатических узлов, возможным поражением коронарных и других висцеральных артерий. Заболевание встречается преимущественно у детей моложе 5 лет. У пациентов моложе 6 мес он встречается реже и может иметь тяжелое течение. Эти дети имеют высокий риск формирования аневризм коронарных артерий. Отсутствие настороженности в плане возможности развития синдрома Кавасаки в этом возрасте способствует отсроченному лечению и ухудшению прогноза. Синдром Кавасаки должен рассматриваться как вероятная причина продолжительной лихорадки даже у самых маленьких детей. Высокая лихорадка неясного генеза у ребенка первых месяцев и лет жизни в течение 7 дней и более — это показание к эхокардиографии с исследованием коронарных артерий. В представленном обзоре приводится анализ исследований разных лет из США, Канады, Кореи, Тайваня, посвященных особенностям заболевания у детей младше 6 мес, в том числе у новорожденных.

Kawasaki syndrome is an acute systemic disease. It is clinically characterized by fever, changes in the mucous membranes, skin, lymph nodes, and possible involvement of coronary and other visceral arteries. The disease is encountered mainly in children less than 5 years of age. In the patients aged less than 6 months it occurs less frequently and may be severe. These babies are at high risk for coronary artery aneurysms. The lack of alertness to the possible development of Kawasaki syndrome at this age delays treatment and worsens prognosis. The Kawasaki syndrome should be considered as a possible cause of prolonged fever even in youngest infants. High fever of unclear genesis in a baby within the first months and 7 days or more of life is an indication for echocardiographic examination of the coronary arteries. The presented review analyzes the studies conducted in different years in the USA, Canada, Korea, and on the specific features of the disease in infants less than 6 months, including in neonates.

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The authors declare that there are no conflicts of interest present.