perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2014-59-6-17-27perinatology-277Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWSВлияние грелина на метаболические процессы и артериальное давление у детейEffect of ghrelin on metabolic processes and blood pressure in childrenКаладзеН. Н.KaladzeN. N.

д.м.н., проф., зав. каф. педиатрии с курсом физиотерапии Крымского государственного медицинского университета имени. СИ. Георгиевского

АлешинаО. К.AlyoshinaO. K.

к.м.н., асе. каф. пропедевтики педиатрии указанного учреждения 295006 Республика Крым, Симферополь, бульвар Ленина, д. 5/7

РевенкоН. А.RevenkoN. A.

к.м.н., доц. той же каф.

Крымский государственный медицинский университет им. СИ. Георгиевского, СимферопольРоссияS.I. Georgiyevsky Crimean State Medical University, SimferopolRussian Federation2014170320165964651Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20162016Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/277

В обзоре литературы отражены результаты современных научных работ, осветивших роль грелина в метаболических процессах. Он стимулирует потребление пиши и участвует в регуляции энергетического гомеостаза, углеводного обмена, массы организма, что позволяет в будущем синтезировать лечебные вакцины на его основе. Грелин непосредственно воздействует на состояние сердечно-сосудистой системы и уровень артериального давления. Обозначены многочисленные влияния гормона на функцию желудочно-кишечного тракта. Гормон обладает мощном противовоспалительной активностью. Описано его воздействие на процессы обучения, возможное участие в патогенезе депрессии и нейродегенеративных заболеваний.

The review of the literature shows the results of current researches dealing with the role of ghrelin in metabolic processes. Ghrelin stimulates food intake and is involved in the regulation of energy homeostasis, carbohydrate metabolism, body weight, which allows this drug-based therapeutic vaccines to be further synthesized. The agent acts directly on the cardiovascular system and blood pressure. Numerous effects of the hormone on the function of the gastrointestinal tract are indicated. The hormone has a potent anti-inflammatory effect. Its action on learning processes and its possible involvement in the pathogenesis of depression and neuro-degenerative diseases are described.

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The authors declare that there are no conflicts of interest present.