perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2016-61-3-18-28perinatology-327Research ArticleКАРДИОЛОГИЯCARDIOLOGYСостояние правых отделов сердца у детей с гиперволемией малого круга кровообращенияRight chambers of the heart in children with pulmonary circulation hypervolemiaЕмельянчикЕ. Ю.EmelyanchikE. Yu.

д.м.н., проф. каф. педиатрии

СалминаА. Б.SalminaA. B.

д.м.н., проф., зав.каф. биологической химии с курсом медицинской, фармацевтической и токсикологической химии, проректор по инновационному развитию и международной деятельности

ВольфН. Г.VolfN. G.

врач консультативной поликлиники

КирилловаЕ. П.KirillovaE. P.

к.м.н., доц. каф. педиатрии

СаковичВ. А.SakovichV. A.

д.м.н., проф., зав. каф. и клиникой сердечно-сосудистой хирургии,

гл. врач,

660022 Красноярск, ул. Партизана Железняка, д.1

Krasnoyarsk

ЛеонтьеваМ. П.LeontyevaM. P.

врач отделения функциональной диагностики

КачановаТ. В.KachanovaT. V.

врач отделения функциональной диагностики

СтоляровД. П.StolyarovD. P.

к.м.н., зав. отд. рентгенхирургических методов диагностики и лечения

Krasnoyarsk

СахновЕ. В.SakhnovE. V.

врач отд. рентгенхирургических методов диагностики и лечения

Krasnoyarsk

БасаловаЕ. В.BasalovaE. V.

врач отделения функциональной диагностики

Krasnoyarsk

КузминыхЕ. Н.KuzminykhE. N.

врач кардиохирургического отделения,

660077 Красноярск, ул. Караульная, д. 45

Krasnoyarsk

ДроботД. Б.DrobotD. B.

д.м.н., проф. кафедры сердечно-сосудистой хирургии того же учреждения, рук. научно-методического отдела

Krasnoyarsk

АверьяноваО. В.AveryanovaO. V.

врач,

660074 Красноярск, ул. Киренского, д. 2а

ДоможаковаО. А.DomozhakovaO. A.

врач,

655012 Хакассия, г. Абакан, ул. Ленина, д. 23

ГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава РФРоссияProf. V.F. Voino-Yasenetsky, Krasnoyarsk State Medical University, Ministry of Health of the Russian FederationRussian FederationКГБУЗ «Красноярский краевой клинический центр охраны материнства и детства»РоссияKrasnoyarsk Territorial Clinical Center for Maternal and Child CareRussian FederationГБОУ ВПО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого»; ФГБУ «Федеральный центр сердечно-сосудистой хирургии» Минздрава РФРоссияFederal Center of Cardiovascular Surgery, Ministry of Health of the Russian FederationRussian FederationФГБУ «Федеральный центр сердечно-сосудистой хирургии» Минздрава РФ 660022 Красноярск, ул. Партизана Железняка, д.1РоссияFederal Center of Cardiovascular Surgery, Ministry of Health of the Russian FederationRussian FederationФГБУ «Федеральный центр сердечно-сосудистой хирургии» Минздрава РФРоссияFederal Center of Cardiovascular Surgery, Ministry of Health of the Russian FederationRussian FederationГБУЗ РХ «Республиканская клиническая больница им. Г.Я. Ремишевской»РоссияG.Ya. Remishevskaya Republican Clinical HospitalRussian Federation2016020720166136575Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20162016Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/327

Проведен анализ ультразвуковых и ангиографических показателей правых отделов сердца у детей с легочной артериальной гипертензией, ассоциированной с врожденными пороками сердца. Исследование проведено в зависимости от функционального класса (выраженности) легочной гипертензии. Установлено, что ремоделирование правых отделов в большей степени зависит от постнагрузки (систолического давления в легочной артерии и легочного сосудистого сопротивления), причем диастолическая дисфункция формируется уже при умеренной легочной гипертензии (II функциональный класс). Выявлено, что на фоне врожденных пороков с артериальной гипоксемией отмечается более быстрое развитие легочной артериальной гипертензии с нарушением систолодиастолической функции миокарда.

The ultrasound and angiographic parameters of the right chambers of the heart were analyzed in children with pulmonary arterial hypertension (PAH) associated with congenital heart defects. The investigation was conducted in relation to the functional class (degree) of PAH. Right cardiac remodeling was found to depend to a greater extent on afterload (pulmonary artery systolic pressure and pulmonary vascular resistance); moreover, diastolic dysfunction developed just in moderate (Functional Class II) PAH. It was ascertained that there was a prompter development of PAH with myocardial systolic and diastolic dysfunction in the presence of congenital malformations with arterial hypoxemia.

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The authors declare that there are no conflicts of interest present.