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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">perinatology</journal-id><journal-title-group><journal-title xml:lang="ru">Российский вестник перинатологии и педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1027-4065</issn><issn pub-type="epub">2500-2228</issn><publisher><publisher-name>Ltd. “The National Academy of Pediatric Science and Innovation”</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">perinatology-47</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Патогенетические механизмы развития идиопатического нефротического синдрома с минимальными изменениями</article-title><trans-title-group xml:lang="en"><trans-title>Pathogenetic mechanisms of idiopathic minimal-change nephrotic syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Обухова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Obukhova</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>н.с. отделения наследственных и приобретенных болезней почек</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский клинический институт педиатрии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Clinical Institute of Pediatrics, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>03</day><month>03</month><year>2016</year></pub-date><volume>59</volume><issue>4</issue><fpage>10</fpage><lpage>15</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ltd. “The National Academy of Pediatric Science and Innovation”, 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><copyright-holder xml:lang="en">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><license xlink:href="https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://www.ped-perinatology.ru/jour/article/view/47">https://www.ped-perinatology.ru/jour/article/view/47</self-uri><abstract><p>Представлены данные литературы о патогенетических механизмах развития нефротического синдрома с минимальными изменениями, а также описаны клинические и гистологические признаки, особенности течения и принципы лечения.</p></abstract><trans-abstract xml:lang="en"><p>The paper presents the data available in the literature on the pathogenetic mechanisms of minimal-change nephrotic syndrome and also describes its clinical and histological signs, course, and treatment principles.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>нефротический синдром</kwd><kwd>патогенетические механизмы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>nephrotic syndrome</kwd><kwd>pathogenic mechanisms</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lombel R.M., Gipson D.S, Hodson E.M. 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