perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2017-62-5-203-209perinatology-578Research ArticleОБМЕН ОПЫТОМSHARING EXPERIENCESЭкссудативная энтеропатия у детей: причины, диагностика и терапияExudative enteropathy in children: causes, diagnosis and therapyКамаловаА. А.KamalovaA. A.

д.м.н., доцент кафедры госпитальной педиатрии с курсом поликлинической  педиатрии Казанского государственного медицинского университета

420012 Казань, ул. Бутлерова, д. 49

НизамоваР. А.NizamovaR. A.

врач-педиатр, гастроэнтеролог, зав. диагностическим отделением Детской республиканской клинической больницы

420011 Казань, ул. Оренбургский тракт, д.140

ХадиеваГ. М.KhadievaG. M.

врач-педиатр, гастроэнтеролог диагностического отделения Детской республиканской клинической больницы

420011 Казань, ул. Оренбургский тракт, д.140

ЗайнетдиноваМ. Ш.ZaynetdinovaM. Sh.

врач-педиатр, гастроэнтеролог диагностического отделения Детской республиканской клинической больницы

420011 Казань, ул. Оренбургский тракт, д.140

ФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РоссииРоссияKazan State Medical University, Ministry of Health of the Russian FederationRussian FederationГАУЗ «Детская республиканская клиническая больница» Минздрава Республики ТатарстанРоссияRepublican Clinical Hospital, Ministry of Health of the Republic of TatarstanRussian Federation201712112017625203209Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20172017Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/578

В статье обсуждаются вопросы этиологии, патогенеза, диагностики и терапии экссудативной энтеропатии у детей, приводятся собственные клинические наблюдения. Экссудативная энтеропатия характеризуется чрезмерной потерей белков через желудочно-кишечный тракт и является редким осложнением различных гастроинтестинальных заболеваний. Клиническая симптоматика разнообразна в зависимости от ведущей причины патологии, но в основном проявляется отеками вследствие гипопротеинемии. При наличии экссудативной энтеропатии следует исключить такие причины гипопротеинемии, как недостаточность питания, нарушение синтеза или потери белка вследствие заболеваний других органов – почек, печени или кожи. Определение причины экссудативной энтеропатии – ключ к ее лечению. Терапия экссудативной энтеропатии включает поддержание нутритивного статуса больного с помощью диеты с высоким содержанием белка и лечение основного заболевания. При энтеропатии, связанной с лимфангиэктазией, рекомендуется диета с низким содержанием жиров, содержащая среднецепочечные триглицериды.

The article discusses the issues of etiology, pathogenesis, diagnosis and therapy of exudative enteropathy in children, and provides his own clinical observations. Exudative enteropathy is characterized by excessive loss of proteins through the gastrointestinal tract and is a rare complication of various gastrointestinal diseases. Clinical symptomatology is diverse depending on the leading cause of the pathology, but is mainly manifested by edema due to hypoproteinemia. In the presence of exudative enteropathy, it is necessary to exclude such causes of hypoproteinemia as malnutrition, a violation of synthesis or loss of protein due to diseases of other organs – kidney, liver or skin. The definition of the cause of exudative enteropathy is the key to its treatment. Therapy of exudative enteropathy involves maintaining the nutritional status of the patient with a diet high in protein and treating the underlying disease. With enteropathy associated with lymphangiectasia, a low-fat diet containing medium chain triglycerides is recommended.

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The authors declare that there are no conflicts of interest present.