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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">perinatology</journal-id><journal-title-group><journal-title xml:lang="ru">Российский вестник перинатологии и педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1027-4065</issn><issn pub-type="epub">2500-2228</issn><publisher><publisher-name>Ltd. “The National Academy of Pediatric Science and Innovation”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21508/1027-4065-2017-62-6-16-22</article-id><article-id custom-type="elpub" pub-id-type="custom">perinatology-586</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕРСОНАЛИЗИРОВАННАЯ ПЕДИАТРИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PERSONALIZED PEDIATRICS</subject></subj-group></article-categories><title-group><article-title>ПЕРСОНАЛИЗИРОВАННАЯ МЕДИЦИНА: ГЕНОМ, ЭЛЕКТРОННОЕ ЗДРАВООХРАНЕНИЕ  И ИНТЕЛЛЕКТУАЛЬНЫЕ СИСТЕМЫ.  ЧАСТЬ 2. МОЛЕКУЛЯРНАЯ ГЕНЕТИКА И МЕТОДЫ ИНТЕЛЛЕКТУАЛЬНОГО АНАЛИЗА</article-title><trans-title-group xml:lang="en"><trans-title>PERSONALIZED MEDICINE: GENOME, ELECTRONIC HEALTH AND INTELLIGENT SYSTEMS.  PART 2. MOLECULAR GENETICS AND METHODS OF INTELLECTUAL ANALYSIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3459-8851</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кобринский</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kobrinskii</surname><given-names>B. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кобринский Борис Аркадьевич – доктор медицинских наук, профессор, зав. лабораторией систем поддержки принятия клинических решений.</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт современных информационных технологий в медицине Федерального исследовательского центра «Информатика и управление» РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Modern Information Technologies in Medicine, Federal Research Center “Computer Science and Control”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>11</day><month>01</month><year>2018</year></pub-date><volume>62</volume><issue>6</issue><fpage>16</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ltd. “The National Academy of Pediatric Science and Innovation”, 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><copyright-holder xml:lang="en">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><license xlink:href="https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://www.ped-perinatology.ru/jour/article/view/586">https://www.ped-perinatology.ru/jour/article/view/586</self-uri><abstract><p>Переход к персонализированной медицине в практическом плане должен сочетать исследование проблемы молекулярно-генетической предрасположенности к заболеваниям с анализом переходных состояний в организме в направлении возможной  патологии. Классификация и контроль состояния могут эффективно осуществляться с использованием методов искусственного интеллекта. Рассматриваются различные интеллектуальные подходы в разных условиях контроля за пациентами.</p></abstract><trans-abstract xml:lang="en"><p>The transition to personalized medicine in practical terms should combine the problems of molecular-genetic predisposition to diseases with transient states in the organism in the direction of possible pathology. Classification and monitoring of the state can be  effectively carried out using artificial intelligence methods. Various intellectual approaches are considered in different conditions for  monitoring patient.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>персонализированная медицина</kwd><kwd>геномика</kwd><kwd>электронное здравоохранение</kwd><kwd>методы искусственного интеллекта</kwd><kwd>персоно-центрированная парадигма</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>personalized medicine</kwd><kwd>genomics</kwd><kwd>e-health</kwd><kwd>artificial intelligence methods</kwd><kwd>person-centered paradigm</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кобринский Б.А. 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