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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">perinatology</journal-id><journal-title-group><journal-title xml:lang="ru">Российский вестник перинатологии и педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1027-4065</issn><issn pub-type="epub">2500-2228</issn><publisher><publisher-name>Ltd. “The National Academy of Pediatric Science and Innovation”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21508/1027-4065-2017-62-6-57-61</article-id><article-id custom-type="elpub" pub-id-type="custom">perinatology-591</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ. ПЕРИНАТОЛОГИЯ И НЕОНАТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES. PERINATOLOGY AND NEONATOLOGY</subject></subj-group></article-categories><title-group><article-title>ЭФФЕКТИВНОСТЬ РАННЕГО ПРИМЕНЕНИЯ СПОНТАННОГО ДЫХАНИЯ ПОД ПОСТОЯННЫМ ПОЛОЖИТЕЛЬНЫМ ДАВЛЕНИЕМ У НЕДОНОШЕННЫХ С ОЧЕНЬ НИЗКОЙ МАССОЙ ТЕЛА ПРИ РОЖДЕНИИ</article-title><trans-title-group xml:lang="en"><trans-title>EFFECTIVENESS OF EARLY USE OF SPONTANEOUS RESPIRATION UNDER CONTINUOUS POSITIVE AIRWAY PRESSURE IN PREMATURE INFANTS WITH VERY LOW BODY WEIGHT AT BIRTH</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хасанова</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Khasanova</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Батманов</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Batmanov</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Батманов  Артем Леонидович – врач отделения  анестезиологии, реанимации и интенсивной терапии.</p><p>700140 Ташкент, Юнусабадский район,  ул. Богишамол, д. 223</p></bio><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Республиканский перинатальный центр Министерства здравоохранения Республики Узбекистан</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Republican Perinatal Center of the Ministry of Health  of the Republic of Uzbekistan</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>12</day><month>01</month><year>2018</year></pub-date><volume>62</volume><issue>6</issue><fpage>57</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ltd. “The National Academy of Pediatric Science and Innovation”, 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><copyright-holder xml:lang="en">Ltd. “The National Academy of Pediatric Science and Innovation”</copyright-holder><license xlink:href="https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://www.ped-perinatology.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://www.ped-perinatology.ru/jour/article/view/591">https://www.ped-perinatology.ru/jour/article/view/591</self-uri><abstract><p>Представлены результаты сравнительного анализа различных методик респираторной терапии для лечения синдрома дыхательных расстройств у недоношенных с очень низкой массой тела при роджении. Исследования  проводились в Республиканском перинатальном центре Министерства здравоохранения Республики Узбекистан.  В исследование были включены новорожденые с массой тела 1001–1500 г (срок гестации 29–31 нед) и респираторными дистресс-синдромом при рождении. Детям 1-й группы лечение проводилось путем раннего, с этапа родильного зала применения методики СРАР; недоношенные 2-й группы были рождены до начала применения данной методики. При сравнительном изучении когорт новорожденных, лечившихся в отделении в течение двух периодов,  отличающихся различными подходами к респираторной терапии, получены результаты, свидетельствующие о том, что большинство недоношенных с очень низкой массой тела и респираторным дистрессом  могут успешно лечиться назальным СРАР, особенно при раннем его использовании без применения механической вентиляции.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the results of a comparative analysis of various methods of respiratory therapy for the treatment of respiratory distress syndrome in premature infants with very low body weight at birth. The studies were conducted in the Republican perinatal center of the Ministry of health of the Republic of Uzbekistan. The study included newborns with very low body weight (1000-1500 g) and with a gestation age of 29-31 weeks, with respiratory distress syndrome at birth. Two groups of newborns were compared. Children of the 1st group have been treated by early, stage delivery room use of CPAP technique; premature infants of the 2nd group were born prior to the application of this technique. In a compative study of the cohorts of newborns treated in the department for two time periods, characterized by different approaches to respiratory therapy, results have been obtained indicating that the majority of premature infants with very low body weight and respiratory distress can be successfully treated with nasal CPAP, without the use of mechanical ventilation, especially in its early use.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>недоношенные</kwd><kwd>очень низкая масса тела</kwd><kwd>респираторный дистресс-синдром</kwd><kwd>респираторная терапия</kwd><kwd>СРАР</kwd></kwd-group><kwd-group xml:lang="en"><kwd>premature infants</kwd><kwd>very low body weight</kwd><kwd>respiratory distress syndrome</kwd><kwd>respiratory therapy</kwd><kwd>CPAP</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Jobe A.H., Ikegami M. Mechanisms initiating lung injury in the preterm. Early Human Development 1998; 53: 81–94.</mixed-citation><mixed-citation xml:lang="en">Jobe A.H., Ikegami M. Mechanisms initiating lung injury in the preterm. Early Human Development 1998; 53: 81–94.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Jacobson T., Grоnvall J., Petersen S., Andersen G.E. «Minitouch» treatment of very low birthweight infants. Acta Pediatr.1993;82:934–938.</mixed-citation><mixed-citation xml:lang="en">Jacobson T., Grоnvall J., Petersen S., Andersen G.E. «Minitouch» treatment of very low birthweight infants. Acta Pediatr.1993;82:934–938.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Gneenough А. Optmal strategies for newborn ventilation – a sintesis of evidence. Early Human Development (2005) 81,957–964.</mixed-citation><mixed-citation xml:lang="en">Gneenough А. Optmal strategies for newborn ventilation – a sintesis of evidence. Early Human Development (2005) 81,957–964.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Thomson M.A., Yoder B.A., Winter V.T., Martin H., Catland D., Siler-Khodr T.M., Coalson J.J. Treatment of immature baboons for 28 days with early nasal continuouspositive airway pressure. Am J Respir Crit Care Med 2004; 169: 1054–62.</mixed-citation><mixed-citation xml:lang="en">Thomson M.A., Yoder B.A., Winter V.T., Martin H., Catland D., Siler-Khodr T.M., Coalson J.J. Treatment of immature baboons for 28 days with early nasal continuouspositive airway pressure. Am J Respir Crit Care Med 2004; 169: 1054–62.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Van Marter L.J., Allred E.N., Pagano M., Sanocka U., Parad R., Moore M., Susser M., Paneth N., Leviton A. Do clinical markers of barotrauma and oxygen toxicity explain interhospitalvariation in rates of chronic lung disease? Pediatrics. 2000; 105: 1194–1201.</mixed-citation><mixed-citation xml:lang="en">Van Marter L.J., Allred E.N., Pagano M., Sanocka U., Parad R., Moore M., Susser M., Paneth N., Leviton A. Do clinical markers of barotrauma and oxygen toxicity explain interhospitalvariation in rates of chronic lung disease? Pediatrics. 2000; 105: 1194–1201.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Avery M., Tooley W., Keller J., Hurd S.S., Bryan M.H., Cotton R.B. et al. Is chronic lung disease in low birth weight infants preventable? A survey of eight centers.Pediatrics. 1987; 79: 26–30.</mixed-citation><mixed-citation xml:lang="en">Avery M., Tooley W., Keller J., Hurd S.S., Bryan M.H., Cotton R.B. et al. Is chronic lung disease in low birth weight infants preventable? A survey of eight centers.Pediatrics. 1987; 79: 26–30.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">de Klerk A.M., de Klerk R.K. Nasal continuous positive airway pressure and outcomes in preterm infants J Pediatr ChildHealth. 2001; 37: 161–167.</mixed-citation><mixed-citation xml:lang="en">de Klerk A.M., de Klerk R.K. Nasal continuous positive airway pressure and outcomes in preterm infants J Pediatr ChildHealth. 2001; 37: 161–167.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Байбарина Е.Н., Антонов А.Г., Ионов О.В. Раннее применение назального СДППД с вариабельным потоком у недоношенных со сроком гестации 28–32 недели. Интенсивная терапия. 2006; 2: 12–13. [Bajbarina E.N., Antonov A.G., Ionov O.V. Early application of nasal СРАР with variable flow with a gestation period of 28–32 weeks. Intensive therapy 2006; 2: 12–13. (in Russ)]</mixed-citation><mixed-citation xml:lang="en">Байбарина Е.Н., Антонов А.Г., Ионов О.В. Раннее применение назального СДППД с вариабельным потоком у недоношенных со сроком гестации 28–32 недели. Интенсивная терапия. 2006; 2: 12–13. [Bajbarina E.N., Antonov A.G., Ionov O.V. Early application of nasal СРАР with variable flow with a gestation period of 28–32 weeks. Intensive therapy 2006; 2: 12–13. (in Russ)]</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Окоев Г.Г., Мазманян П.А. Постоянное положительное давление в дыхательных путях при лечении респираторных растройств у новорожденных. Ереван: АРТ 2006, 32. [Okoev G.G., Mazmanjan P.A. Constant positive airway pressure in the treatment of respiratory disorders in newborns. Yerevan: ART 2006, 32. (in Russ)]</mixed-citation><mixed-citation xml:lang="en">Окоев Г.Г., Мазманян П.А. Постоянное положительное давление в дыхательных путях при лечении респираторных растройств у новорожденных. Ереван: АРТ 2006, 32. [Okoev G.G., Mazmanjan P.A. Constant positive airway pressure in the treatment of respiratory disorders in newborns. Yerevan: ART 2006, 32. (in Russ)]</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Finer N.N., Carlo W.A., Duara S., Fanaroff A.A., Donovan E.F., Wright L.L., Kandefer S., Poole W.K. Delivery room continuous positive airway pressure/positive end-expiratory pressurein extremely low birth weight infants: a feasibility trial. Pediatrics 2004; 114: 651–657.</mixed-citation><mixed-citation xml:lang="en">Finer N.N., Carlo W.A., Duara S., Fanaroff A.A., Donovan E.F., Wright L.L., Kandefer S., Poole W.K. Delivery room continuous positive airway pressure/positive end-expiratory pressurein extremely low birth weight infants: a feasibility trial. Pediatrics 2004; 114: 651–657.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Downes J.J., Vidyasagar D., Morrow G.M., Boggs T.R. Respiratory distress syndrome of newborn infants. New clinical scoring system with acid base and blood gas correlation. Clin Pediatr 1970; 9: 325–330.</mixed-citation><mixed-citation xml:lang="en">Downes J.J., Vidyasagar D., Morrow G.M., Boggs T.R. Respiratory distress syndrome of newborn infants. New clinical scoring system with acid base and blood gas correlation. Clin Pediatr 1970; 9: 325–330.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Richmond S. ILCOR and neonatal resuscitation 2005. Arch Dis Child Fetal Neonatal Ed 2007; 92: F163–165.</mixed-citation><mixed-citation xml:lang="en">Richmond S. ILCOR and neonatal resuscitation 2005. Arch Dis Child Fetal Neonatal Ed 2007; 92: F163–165.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">MorleyC.J., Davis P.G., Doyle L.W., Brion L.P., Hascoet J.-M., Carlin J.B., COIN Trial Investigators. Nasal CPAP or intubation at birth for very preterm infants. N Engl J Med 2008; 358; 700–708. DOI:10.1056/NEJMoa072788</mixed-citation><mixed-citation xml:lang="en">MorleyC.J., Davis P.G., Doyle L.W., Brion L.P., Hascoet J.-M., Carlin J.B., COIN Trial Investigators. Nasal CPAP or intubation at birth for very preterm infants. N Engl J Med 2008; 358; 700–708. DOI:10.1056/NEJMoa072788</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">SUPPORT study group of the Eunice Kennedy Shriver NICHD Neonatal Research Network, Finer N.N., Carlo W.A., Walsh M.C., Rich W., Gantz M.G., Laptook A.R. et al. Early CPAP versus surfactant in extremely preterm infants. N Engl J Med 2010; 362(21): 1970–1979. DOI: 10.1056/NEJMoa0911783</mixed-citation><mixed-citation xml:lang="en">SUPPORT study group of the Eunice Kennedy Shriver NICHD Neonatal Research Network, Finer N.N., Carlo W.A., Walsh M.C., Rich W., Gantz M.G., Laptook A.R. et al. Early CPAP versus surfactant in extremely preterm infants. N Engl J Med 2010; 362(21): 1970–1979. DOI: 10.1056/NEJMoa0911783</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
