perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2018-63-4-15-22perinatology-691Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWSАНАФИЛАКСИЯ И ВАКЦИНАЦИЯ: РИСКИ И РЕАЛИИANAPHYLAXIS AND VACCINATION: RISKS AND REALITIEShttps://orcid.org/0000-0002-6231-246XРубанА. П.RubanA. P.

к.м.н., доцент кафедры поликлинической педиатрии,

220013 Минск, ул. П.Бровки, д.3, корп.3

ПампураА. Н.PampuraA. N.

д.м.н., зав. отделом аллергологии и клинической иммунологии,

125412 Москва, ул. Талдомская, д. 2

ГУО «Белорусская медицинская академия последипломного образования»БеларусьBelarusian Medical Academy of Postgraduate EducationBelarusОСП «Научно-исследовательский клинический институт педиатрии имени академика Ю.Е. Вельтищева» ФГБОУ ВО РНИМУ им. Н.И.Пирогова Минздрава РФРоссияResearch and Clinical Institute for Pediatrics named after Academician Yu.E. Veltischev of the Pirogov Russian National Research Medical University of the Ministry of Health of the Russian FederationRussian Federation2018090920186341522Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20182018Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/691

Статья посвящена проблеме анафилаксии в  поствакцинальный период. Представлены данные о  частоте ее распространенности и летальности в зависимости от вида вакцины. Обозначены варианты клинической картины анафилаксии и дифференциально-диагностические подходы. Перечислены основные причинно-значимые компоненты вакцин, индукторы анафилаксии, а также методы их идентификации. Рассмотрены терапевтические подходы, обозначены ложные мифы и противопоказания к вакцинации. Обобщен опыт по проведению превентивных индивидуальных мер.

The article is about the problem of anaphylaxis in the post-vaccination period. Data on the frequency of its prevalence and lethality depending on the type of vaccine are presented. Variants of a clinical picture of anaphylaxis and differential-diagnostic approaches are indicated. The major causal components of vaccines, anaphylaxis inducers, and methods for their identification are mentioned. Therapeutic approaches are analyzed, false myths and contraindications to vaccination are indicated. The experience of carrying out preventive individual measures is generalized.

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The authors declare that there are no conflicts of interest present.