perinatologyРоссийский вестник перинатологии и педиатрииRossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)1027-40652500-2228Ltd. “The National Academy of Pediatric Science and Innovation”10.21508/1027-4065-2019-64-1-110-115perinatology-830Research ArticleОБМЕН ОПЫТОМSHARING EXPERIENCESАнализ экспрессии генов по технологии nCounter Nanostring в медицинских исследованиях: опыт использования у детей с нефротическим синдромомAnalysis of gene expression by nCounter Nanostring technology in medical research: experience with children with nephrotic syndromehttps://orcid.org/0000-0002-0942-0103МорозовС. Л.MorozovS. L.

Морозов   Сергей  Леонидович – кандидат медицинских наук,   старший научный сотрудник отдела наследственных и приобретенных болезней  почек.

125412 Москва,  ул Талдомская, д.2.

Moscow.

ВоронковаА. С.VoronkovaA. S.

Воронкова  Анастасия  Сергеевна  – научный сотрудник  лаборатории общей  патологии.

125412 Москва,  ул Талдомская, д.2.

Moscow.

https://orcid.org/0000-0002-3050-7748ДлинВ. В.DlinV. V.

Длин Владимир Викторович – доктор медицинских наук, профессор, заведующий отделом наследственных и приобретенных болезней  почек.

125412 Москва,  ул Талдомская, д.2.

Moscow.

ТуркинаТ. И.TurkinaT. I.

Туркина Татьяна Ивановна – доктор биологических наук, профессор кафедры клинической лабораторной  диагностики.

125412 Москва,  ул Талдомская, д.2.

Moscow.

https://orcid.org/0000-0002-0552-6939СухоруковВ. С.SukhorukovV. S.

Сухоруков  Владимир  Сергеевич  – доктор медицинских наук,  профессор,  заведующий лабораторией  Научного центра неврологии, профессор кафедры  гистологии, эмбриологии РНИМУ им. Н.И. Пирогова.

125412 Москва,  ул Талдомская, д.2.

Moscow.

Научно-исследовательский клинический институт педиатрии им. академика Ю.Е. ВельтищеваРоссияVeltischev Research and Clinical Institute for PediatricsRussian FederationРНИМУ им. Н.И. Пирогова Минздрава РоссииРоссияPirogov Russian National Research Medical UniversityRussian FederationРНИМУ им. Н.И. Пирогова Минздрава России; Научный центр неврологииРоссияPirogov Russian National Research Medical University; Research Center of NeurologyRussian Federation201908032019641110115Copyright © Ltd. “The National Academy of Pediatric Science and Innovation”, 20192019Ltd. “The National Academy of Pediatric Science and Innovation”Ltd. “The National Academy of Pediatric Science and Innovation”https://www.ped-perinatology.ru/jour/about/submissions#copyrightNoticehttps://www.ped-perinatology.ru/jour/article/view/830

В эпоху современной медицины сформировались фундаментальные научные установки в диагностике  широкого круга заболеваний, которые основаны на традиционных инструментах: лабораторных и функциональных исследованиях,  световой микроскопии, иммунофлюоресценции и электронной микроскопии. Однако в последние десятилетия эти методы становятся недостаточными для верификации различных вариантов течения заболеваний, особенно с нетипичной клинической картиной. В статье рассматриваются возможности новой технологии nCounter от компании «Nanostring Technologies»,  подробно описаны возможности технологии в диагностике различных заболеваний, а также приведен собственный опыт использования в диагностике у детей с нефротическим синдромом.

In the era of modern medicine, there are formed the fundamental scientific principles in the diagnosis of a wide range of diseases that are based on traditional instruments: laboratory and functional studies, light microscopy, immunofluorescence, and electron microscopy. However, in recent decades these methods have become insufficient to verify various variants of the diseases, especially with an atypical clinical picture. The article discusses the capabilities of the nCounter technology from the company Nanostring Technologies, it describes in detail the capabilities of the technology in the diagnosis of various diseases, and also the authors present their own experience of using diagnostics in children with nephrotic syndrome.

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The authors declare that there are no conflicts of interest present.