The clinical relevance of the microelements content in newborns after perinatal asphyxia
https://doi.org/10.21508/1027-4065-2019-64-6-53-56
Abstract
Research purpose. To identify the correlation between the clinical signs of neonatal adaptation in the dynamics and the content of trace elements in the serum of newborns of different gestational ages who underwent perinatal asphyxia (main group): 41 premature infants and 27 full-term children.
Results. It was found that there was a direct significant correlation between the concentration of trace elements (Mg, Fe, Zn, Cu), gestational age and Apgar grades (5th minute) in n prematurely born babies during the period of acute adaptation (3-5 days). Reliable feedback was established between the clinical signs of posthypoxic damage to the central nervous system, suppression syndrome and the content of Fe, Mg and Zn, as well as a weakening of muscle tone and the content of Zn and Mg. In full-term babies, the correlation between the content of Fe, Zn, Mg in the blood serum and clinical indicators was expressed more clearly. In these children, a significant positive correlation was observed between the Ca content in the blood and the syndrome of neuro-reflex excitability.
Conclusion. The determination of trace elements in blood serum in newborns in the dynamics of the neonatal period (3-5th and 21-28th days of life) makes it possible to predict the course and severity of hypoxic-ischemic damage to the Central nervous system.
About the Authors
S. Sh. Gasanov
Azerbaijan Medical University
Azerbaijan
Baku
Azerbaijan
Baku
Sh. A. Sadigova
Azerbaijan Medical University
Azerbaijan
Baku
Azerbaijan
Baku
B. A. Babaeva
Azerbaijan Medical University
Azerbaijan
Baku
Azerbaijan
Baku
References
1. Barashnev Yu.I. Perinatal neurology. Moscow: Triada-Х, 2011; 640 (in Russ.)
2. Klimenko T.M., Tarasov I.V. Perinatal hypoxic lesion of the Central nervous system: a modern view of the problem. Voprosy prakticheskoi pediatrii 2013; 1(4): 40–45 (in Russ.)
3. Amritanshy K., Smiris S., Kumor V. Clinical profile and shortterns outcome of hypoxic-ishemice ensefalopathy among birth asphyxiated babies in Kathior Medical Hospital. J Clin Neonatal 2014; 3(4): 195–199.
4. Bryksina E.Yu., Bryksin V.S., Bushtyreva I.O. Pathogenetic aspects of perinatal lesions of the Central nervous system and features of the neurological status of premature infants. Sovremennye problemy nauki obrazovaniya 2015; 4: 410 (in Russ.)
5. Volodin N.N., Medvedev M.N., Gorbunov A.V. Early diagnosis of adverse effects of perinatal hypoxic-ischemic brain lesions in premature infants and optimization of their treatment. Pediatriya. Zhurnal im. G.N. Speranskogo (Pediatria. Journal named after G.N. Speransky) 2010; 19(2): 101–107 (in Russ.)
6. American Academy of Pediatrics, Council on children with Disabilities; Section of Developmental Behavioral Pediatrics. Identifying infants and young children with developmental disorders in the medical home: an algorithm for developmental surveillance and screening. Pediatrics 2006; 118: 405–420. DOI: 10.1542/peds.2006-1231
7. Adebami O.J. Maternal and fetal determinants of mortality in babies with birth asphyxia. Gio Ady Res Med Sci 2015; 4(6): 270–276.
8. Basu P., Som S., Das H., Choudhuri N. Electrolyte status in birth asphyxia. Indian J Pediatr 2010; 77(5): 259–262. DOI: 10.1007/s12098-010-0034-0
9. Babu A.B., Davi S.S., Kumar K.B. Birth asphyxia Incidence and immediate outcome in relation to risk factor and complatous. Int J Res Hith 2014; 4: 1064–1071.
Review
For citations:
Gasanov S.Sh., Sadigova Sh.A., Babaeva B.A. The clinical relevance of the microelements content in newborns after perinatal asphyxia. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2019;64(6):53-56. (In Russ.) https://doi.org/10.21508/1027-4065-2019-64-6-53-56
Views:
794
Email this article 