The lesion of the osteo-articular system in the onset of acute leukemia in childhood
https://doi.org/10.21508/1027-4065-2020-65-5-87-92
Abstract
According to different authors, the osteoarticular syndrome is observed in every third patient with acute leukemia. The polymorphism of the clinical manifestations presents a diagnostic difficulty, while the abnormal x-ray findings are not traditional characteristics of patients with leukemia. In some cases, bone manifestations may be the first and only symptom of acute lymphoblastic leukemia, complicating the diagnosis and postponing the correct diagnosis.
The article describes 3 clinical cases of patients with a lesion of the osteo-articular system in the onset of acute leukemia. Despite the current complex laboratory and instrumental research methods, a particular attention should be paid to the difficulties of differential diagnosis between acute leukemia and other lesions of the osteo-articular system.
About the Authors
A. S. Ulanova
Vyzhletsov Аrkhangelsk Regional Children's Clinical Hospital; Northern State Medical University
Russian Federation
Russian Federation
Arkhangelsk
N. A. Grigoryeva
Vyzhletsov Аrkhangelsk Regional Children's Clinical Hospital; Northern State Medical University
Russian Federation
Russian Federation
Arkhangelsk
I. A. Turabov
Northern State Medical University
Russian Federation
Russian Federation
Arkhangelsk
M. Yu. Rykov
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
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Review
For citations:
Ulanova A.S., Grigoryeva N.A., Turabov I.A., Rykov M.Yu. The lesion of the osteo-articular system in the onset of acute leukemia in childhood. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2020;65(5):87-92. (In Russ.) https://doi.org/10.21508/1027-4065-2020-65-5-87-92
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