Use of statins in children with familial hypercholesterolemia
https://doi.org/10.21508/1027-4065-2020-65-5-139-144
Abstract
Familial hypercholesterolemia Is the most common genetic disease in the world. It is characterized by an increase in the level of total cholesterol and low-density lipoproteins since childhood. It is desired to diagnose and start treatment in childhood prior to development of complications, such as aortic stenosis, atherosclerotic changes in the artery walls. Statins are recommended as the first-line medications. However, due to limited experience, the clinicians have different opinions regarding the age of initiation of hypolipidemic therapy. The article is aimed to critically examine the data on the use of statins in children with familial hypercholesterolemia, their effectiveness and safety available in the world literature.
About the Authors
D. I. Sadykova
Kazan State Medical University
Russian Federation
Russian Federation
M. A. Shkolnikova
Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
L. F. Galimova
Kazan State Medical University; Republican Children's Clinical Hospital
Russian Federation
Russian Federation
E. S. Slastnikova
Kazan State Medical University; Republican Children's Clinical Hospital
Russian Federation
Russian Federation
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For citations:
Sadykova D.I., Shkolnikova M.A., Galimova L.F., Slastnikova E.S. Use of statins in children with familial hypercholesterolemia. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2020;65(5):139-144. (In Russ.) https://doi.org/10.21508/1027-4065-2020-65-5-139-144
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