Analysis of clinical experience of children with toxic epidermal necropysis
R. F. Khakimova,
O. V. Skorokhodkina,
G. M. Zaynetdinova,
G. A. Shamsutdinova,
G. R. Ryzhova,
M. R. Khakimova,
D. A. Volkova https://doi.org/10.21508/1027-4065-2020-65-5-181-186
Abstract
Toxic epidermal necrolysis (TEN) is a severe drug allergy. The objective was to analyze the clinical experience of 17 children of different age with toxic epidermal necrolysis. The authors found that medications against infection diseases were the most common reason for the development of the disease. In some cases we observed the delayed diagnosis, therapy without consideration of causative agents, and wrong doses of corticosteroids. The majority of cases require combined use of corticosteroids and intravenous immunoglobulins, however bacterial complications are possible in some cases.
About the Authors
R. F. Khakimova
Kazan State Medical University
Russian Federation
Russian Federation
O. V. Skorokhodkina
Kazan State Medical University
Russian Federation
Russian Federation
G. M. Zaynetdinova
Children's Republican Clinical Hospital
Russian Federation
Russian Federation
Kazan
G. A. Shamsutdinova
Children's Republican Clinical Hospital
Russian Federation
Russian Federation
Kazan
G. R. Ryzhova
Children's Republican Clinical Hospital
Russian Federation
Russian Federation
Kazan
M. R. Khakimova
Kazan State Medical University
Russian Federation
Russian Federation
D. A. Volkova
Kazan State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Khakimova R.F., Skorokhodkina O.V., Zaynetdinova G.M., Shamsutdinova G.A., Ryzhova G.R., Khakimova M.R., Volkova D.A. Analysis of clinical experience of children with toxic epidermal necropysis. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2020;65(5):181-186. (In Russ.) https://doi.org/10.21508/1027-4065-2020-65-5-181-186
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