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Iliofemoral thrombosis in a patient with recurrent nephrotic syndrome
T. I. Razdolkina,
V. S. Vereshchagina,
L. A. Balykova,
E. F. Moskovskaya,
A. V. Krasnopolskaya,
V. A. Gorbatov,
A. V. Shulepina,
S. S. Ishutkina https://doi.org/10.21508/1027-4065-2023-68-2-93-98
Abstract
Nephrotic syndrome is one of the most common glomerulopathies in children, accompanied by a high risk of thrombosis due to hypoalbuminemia, hypovolemia, hyperlipidemia, hyperfibrinogenemia, and antithrombin III deficiency. The article describes a clinical case of iliofemoral thrombosis in a 16-year-old boy with recurrent nephrotic syndrome and primary thrombophilia (heterozygote F5 — Leiden mutation) was diagnosed. The presented clinical observation indicates the multifactorial origin of thrombotic complications in nephrotic syndrome, caused by a combination of an imbalance between the proand anticoagulant components of the blood coagulation system and individual risk factors (severity of proteinuria, hypoalbuminemia, comorbidity, hereditary thrombophilia), and therefore further study is needed to determine the tactics of prevention and treatment.
About the Authors
T. I. Razdolkina
Ogarev National Research Mordovia State University
Russian Federation
Russian Federation
Saransk
V. S. Vereshchagina
Ogarev National Research Mordovia State University
Russian Federation
Russian Federation
Saransk
L. A. Balykova
Ogarev National Research Mordovia State University
Russian Federation
Russian Federation
Saransk
E. F. Moskovskaya
Republican Children’s Clinical Hospital
Russian Federation
Russian Federation
Saransk
A. V. Krasnopolskaya
Ogarev National Research Mordovia State University
Russian Federation
Russian Federation
Saransk
V. A. Gorbatov
Ogarev National Research Mordovia State University
Russian Federation
Russian Federation
Saransk
A. V. Shulepina
Ogarev National Research Mordovia State University
Russian Federation
Russian Federation
Saransk
S. S. Ishutkina
Ogarev National Research Mordovia State University
Russian Federation
Russian Federation
Saransk
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For citations:
Razdolkina T.I., Vereshchagina V.S., Balykova L.A., Moskovskaya E.F., Krasnopolskaya A.V., Gorbatov V.A., Shulepina A.V., Ishutkina S.S. Iliofemoral thrombosis in a patient with recurrent nephrotic syndrome. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2023;68(2):93-98. (In Russ.) https://doi.org/10.21508/1027-4065-2023-68-2-93-98
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