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Human parechovirus infections in children: modern concepts

https://doi.org/10.21508/1027-4065-2023-68-5-5-10

Abstract

This article is a review of modern ideas about human parechovirus infection in children. At this time human parechoviruses are a common cause of infectious diseases in childhood with clinical presentation of acute gastroenteritis, upper respiratory tract pathology, fever, and rash. Severe forms damaging the central nervous system or the development of sepsis are possible in newborns and infants and are almost exclusively associated with parechovirus A type 3 (HPeV-A3). The infection is transmitted mainly via food and droplet routes. The main method of infection diagnosis is the detection of viral RNA by real-time PCR in cerebrospinal fluid, blood, and feces. No treatment for the parechovirus infection has been developed so far.

About the Authors

A. M. Sabitova
Kazan State Medical University
Russian Federation

Kazan



V. A. Anokhin
Kazan State Medical University
Russian Federation

Kazan



S. V. Khaliullina
Kazan State Medical University
Russian Federation

Kazan



G. R. Fatkullina
Kazan State Medical University
Russian Federation

Kazan



A. E. Evdokimova
Kazan State Medical University
Russian Federation

Kazan



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Review

For citations:


Sabitova A.M., Anokhin V.A., Khaliullina S.V., Fatkullina G.R., Evdokimova A.E. Human parechovirus infections in children: modern concepts. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2023;68(5):5-10. (In Russ.) https://doi.org/10.21508/1027-4065-2023-68-5-5-10

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ISSN 1027-4065 (Print)
ISSN 2500-2228 (Online)