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Sarcopenia in children
https://doi.org/10.21508/1027-4065-2024-69-6-21-26
Abstract
Sarcopenia is characterized by a decline in skeletal muscle mass and muscle function. Skeletal muscle plays a crucial role in metabolism and overall health throughout the lifespan. Emerging evidence indicates that both prenatal (such as maternal diet during pregnancy and genetic factors) and postnatal factors (including physical activity, hormonal levels, nutrition, and various diseases, such as obesity) influence the development of muscle mass and strength early in life. The presence of sarcopenia is associated with adverse outcomes (such as cardiometabolic disorders, non-alcoholic fatty liver disease, cognitive dysfunction, falls and fractures, reduced physical performance and quality of life, as well as disability and mortality) in both children and later in adults. Despite growing research interest in sarcopenia across different ages, a clear pediatric concept and clinical guidelines are currently lacking. The objective of this review is to examine the latest data on sarcopenia in pediatrics, with a specific focus on myokines and their role. The review includes data from the past 5 years sourced from the Elibrary and PubMed databases. The literature search was conducted using keywords: pediatric sarcopenia, sarcopenia in children, skeletal muscle in childhood, myokines in children.
About the Authors
M. V. Matveeva
Siberian State Medical University
Russian Federation
Russian Federation
Tomsk
Yu. G. Samoilova
Siberian State Medical University
Russian Federation
Russian Federation
Tomsk
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Review
For citations:
Matveeva M.V., Samoilova Yu.G. Sarcopenia in children. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2024;69(6):21-26. (In Russ.) https://doi.org/10.21508/1027-4065-2024-69-6-21-26
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