Measles subacute sclerosing panencephalitis in children: past and present

Эпидемиологическая ситуация по кори оставалась нестабильной в последние годы в России и в ряде других стран, сопровождалась подъемом заболеваемости в постковидном периоде, особенно в 2024 г. среди детей до 1 года, что является фактором риска развития крайней тяжелого и малокурабельного осложнения — коревого подострого склерозирующего панэнцефалита, как правило, манифестирующего неврологическими симптомами через 5–7 лет после перенесенной кори. Проведен анализ описательных и систематических научных литературных обзоров, а также других зарубежных и российских публикаций преимущественно за последние 10 лет, посвященных коревому подострому склерозирующему панэнцефалиту, вопросам этиологии, эпидемиологии, патогенеза и рисков развития после перенесенной кори, характерным клиническим симптомам, диагностическим критериям, а также методам лабораторной и инструментальной диагностики (электроэнцефалографии и магнитно-резонансная томографии). Представлены результаты международных исследований по оценке клинической эффективности различных схем терапии коревого подострого склерозирующего панэнцефалита у детей.

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