УЧАСТИЕ ВИТАМИНА D В ПАТОГЕНЕЗЕ ЗАБОЛЕВАНИЙ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ
https://doi.org/10.21508/1027-4065-2018-63-5-43-50
Аннотация
Представлены данные экспериментальных и клинических исследований, посвященных изучению влияния витамина D на возникновение и прогрессирование заболеваний сердечно-сосудистой системы: артериальной гипертензии, атеросклероза, ишемической болезни сердца, нарушений ритма сердца. Результаты исследований свидетельствуют о том, что выраженный дефицит витамина D высоко коррелирует с внезапной сердечной смертью, сердечно-сосудистыми катастрофами, общей смертностью. Снижение содержания витамина D сопровождается повышением уровня общего холестерина, липопротеинов низкой плотности и триглицеридов, повышением частоты сердечных сокращений и систолического артериального давления. Метаанализы рандомизированных контролируемых исследований показали, что включение витамина D в комплекс лечебно-реабилитационных мероприятий, проводимых пациентам с сердечно-сосудистыми заболеваниями, способствует снижению показателей общей смертности.
Об авторах
А. Н. Колесников
ГОО ВПО «Донецкий национальный медицинский университет им. М. Горького».
Украина
Украина
д.м.н., проректор по последипломному образованию, зав. кафедрой анестезиологии, реаниматологии и неонатологии.
А. В. Дубовая
ГОО ВПО «Донецкий национальный медицинский университет им. М. Горького».
Украина
Украина
к.м.н., доцент кафедры педиатрии факультета интернатуры и последипломного образования.
Ю. В. Удовитченко
ГОО ВПО «Донецкий национальный медицинский университет им. М. Горького».
Украина
Украина
ординатор кафедры педиатрии факультета интернатуры и последипломного образования.
83003 Украина, Донецк, пр. Ильича, д. 16.
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Рецензия
Для цитирования:
Колесников А.Н., Дубовая А.В., Удовитченко Ю.В. УЧАСТИЕ ВИТАМИНА D В ПАТОГЕНЕЗЕ ЗАБОЛЕВАНИЙ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ. Российский вестник перинатологии и педиатрии. 2018;63(5):43-50. https://doi.org/10.21508/1027-4065-2018-63-5-43-50
For citation:
Kolesnikov A.N., Dubovaya A.V., Udovitchenko Yu.V. PARTICIPATION OF VITAMIN D IN PATHOGENESIS OF CARDIOVASCULAR DISEASES. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2018;63(5):43-50. (In Russ.) https://doi.org/10.21508/1027-4065-2018-63-5-43-50
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