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PARTICIPATION OF VITAMIN D IN PATHOGENESIS OF CARDIOVASCULAR DISEASES

https://doi.org/10.21508/1027-4065-2018-63-5-43-50

Abstract

The article presents data of experimental and clinical studies devoted to the influence of vitamin D on the origin and progression of the cardiovascular diseases: arterial hypertension, atherosclerosis, coronary heart disease, cardiac rhythm disturbances. The results of the studies indicate that a pronounced deficiency of vitamin D is highly correlated with sudden cardiac death, cardiovascular catastrophes, and overall mortality. The decrease in vitamin D is followed by an increase in total cholesterol, low-density lipoproteins and triglycerides, an increase in the heart rate and the level of systolic blood pressure. The Meta-analyzes of randomized controlled trials demonstrated that the addition of vitamin D to treatment and rehabilitation measures of the patients with cardiovascular disease helps to reduce overall mortality.

About the Authors

A. N. Kolesnikov
Gorky Donetsk National Medical University.
Ukraine


A. V. Dubovaya
Gorky Donetsk National Medical University.
Ukraine


Yu. V. Udovitchenko
Gorky Donetsk National Medical University.
Ukraine


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Review

For citations:


Kolesnikov A.N., Dubovaya A.V., Udovitchenko Yu.V. PARTICIPATION OF VITAMIN D IN PATHOGENESIS OF CARDIOVASCULAR DISEASES. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2018;63(5):43-50. (In Russ.) https://doi.org/10.21508/1027-4065-2018-63-5-43-50

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