Preview

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)

Advanced search

SUBCUTANEOUS ADIPONECROSIS OF A NEWBORN

Abstract

This is the first report of a clinical case of subcutaneous adiponecrosis of a newborn with acute early neonatal period from a mother with risk factors in the form of diabetes, hypoglycemia during pregnancy, chronic infections, emergency surgical delivery due to acute fetal hypoxia. The article contains algorithm of the differential diagnostics of diabetic embryo-fetopathy and metabolic disorders in a newborn from a mother with diabetes.

About the Authors

N. V. Kholodnova
The Speransky Children’s City Clinical Hospital No. 9.
Russian Federation


L. N. Mazankova
Russian Medical Academy of Post-Graduate Education.
Russian Federation


I. E. Turina
Sechenov First Moscow State Medical University (Sechenov University).
Russian Federation


A. A. Volter
Sechenov First Moscow State Medical University (Sechenov University).
Russian Federation


L. M. Makarova
The Speransky Children’s City Clinical Hospital No. 9.
Russian Federation


O. V. Tsilinskaya
The Speransky Children’s City Clinical Hospital No. 9.
Russian Federation


References

1. Tran J.T., Sheth A.P. Complications of subcutaneous fat necrosis of the newborn: a case report and review of the literature. Pediatr Dermatol 2003; 20: 257–261.

2. Sultana J., Yasmeen S., Nazme N.I., Moslem M.H.M., Haque Z.S.M., Fatema N.N. Subcutaneous fat necrosis of the newborn Clinical: A Case Reports. J Bangladesh Coll Phys Surg 2017; 35: 192–195. DOI: 10.3329/jbcps.v35i4.34740

3. Pérez Martínez E., Camprubí Camprubí M., Ramos Cebrián M., Antón López J., Apodaca Saracho A., Lopez Ramos M.G., García-Alix A. Treatment with bisphosphonates in severe hypercalcemia due to subcutaneous fat necrosis in an infant with hypoxic-ischemic encephalopathy. J Perinatol 2014; 34: 492–493. DOI: 10.1038/jp.2014.28

4. Grass B., Weibel L., Hagmann C., Brotschi B. Subcutaneous fat necrosis in neonates with hypoxic ischaemic encephalopathy registered in the Swiss National Asphyxia and Coolling Register. BMC Pediatrics 2015; 15: 73. DOI: 10.1186/s12887-015-0395-7

5. Chen T.H., Shewmake S.W., Hansen D.D., Lacey H.L. Subcutaneous fat necrosis of the newborn. Arch Dermatol 1981; 117: 36–37.

6. Oswalt G.C., Montes L.F., Cassady G. Subcutaneous fat necrosis of the newborn. J Cutan Pathol 1978; 5: 193–199.

7. Lewis A., Cowen P., Rodda C., Dyall-Smith D. Subcutaneous fat necrosis of the newborn complicated by hypercalcemia and thrombocytopenia. Aust J Dermatol 1992; 33: 141–144.

8. Sharata H., Postellon D.C., Hashimoto K. Subcutaneous fat necrosis, hypercalcemia, and prostaglandin E. Pediatr Dermatol 1995;12: 43–47.

9. Wolach B., Raas-Rothschild A., Vogel R., Chock L., Metzker A. Subcutaneous fat necrosis with thrombocytopenia in a newborn infant. Dermatologica 1990; 181: 54–55.

10. Farooque A., Moss C., Zehnder D., Hewison M., Shaw N.J. Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in subcutaneous fat necrosis. Br J Dermatol 2009; 160(2): 423–425.

11. Fretzin D.F., Arias A.M. Sclerema neonatorum and subcutaneous fat necrosis of the newborn. Pediatr Dermatol 1987; 4: 112–122.

12. Lusk R., Greiman M. Subcutaneous fat necrosis in infancy. Otolaryngol Head Neck Surg 1988; 99: 520–523.

13. Mather M.K., Sperling L.C., Sau P. Subcutaneous fat necrosis of the newborn. Int J Dermatol 1997; 36: 435–452.

14. Gu L.L., Daneman A., Binet A., Kooh S.W. Nephrocalcinosis and nephrolithiasis due to subcutaneous fat necrosis with hypercalcemia in two full-term asphyxiated neonates: sonographic findings. Pediatr Radiol 1995; 25: 142–144.

15. Caple J.I., Reyes S. Subcutaneous fat necrosis of the newborn: a case presentation. J Perinatol 1996; 16: 140– 141.

16. Burden A.D., Krafchik B.R. Subcutaneous fat necrosis of the newborn: a review of 11 cases. Pediatr Dermatol 1999; 16:384–387.

17. Mahe E., Girszyn N., Hadj-Rabia S., Bodemer C., Hamel-Teillac D., De Prost Y. Subcutaneous fat necrosis of the newborn: a systematic evaluation of risk factors, clinical manifestations, complications and outcome of 16 children. Br J Dermatol 2007; 156: 709–715.

18. Janssens P.M., Vonk J., Demacker P.N.M. Hypertriglyceridemia in a case of subcutaneous fat necrosis in a newborn. Ann Clin Biochem 1993;.30:.482–484.

19. Vonk J., Janssens P.M.W., Demacker P.N.M., Folkers E. Subcutaneous fat necrosis in a neonate, in association with aberrant plasma lipid and lipoprotein values. J Pediatr 1993; 123: 462–464.

20. Noojin R.O., Pace B.F., Davis H.G. Subcutaneous fat necrosis of the newborn. Certain etiologic considerations. J Invest Dermatol 1949; 12: 331.

21. Horsfield G.I., Yardley H.T. Sclerema neonatorum. J Invest Dermatol 1965; 44: 326–332.

22. Calisici E., Oncel M.Y., Degirmencioglu H., Sandal G., Canpolat F.E., Erdeve O. et al. A neonate with subcutaneous fat necrosis after passive cooling: does polycythemia have an effect? Case Rep Pediatr 2013; 2013: 254089. DOI: 10.1155/2013/254089

23. Canpolat N., Özdil M., Kuruğoğlu S., Çalışkan S., Sever L. Nephrocalcinosis as a complication of subcutaneous fat necrosis of the newborn. Turk J Pediatr 2012; 54: 667–670.

24. Dudink J., Waither F.J., Beekman R.P. Subcutaneous fat necrosis of the newborn: hypercalcaemia with hepatic and atrial myocardial calcification. Arch Dis Child Fetal Neonatal 2003; 88: 343–345.

25. Drut R., Drut R.M., Greco M.A. Massive myocardial calcification in the perinatal period. Pediatr Dev Pathol 1998; 1: 366–374.

26. Norwood-Galloway A., Lebwohl M., Phelps R., Raucher H. Subcutaneous fat necrosis of the newborn with hypercalcemia. J Am Acad Dermatol 1987; 16: 435–439.

27. Finne P.H., Sanderud J., Aksnes L., Bratlid D., Aarskog D. Hypercalcemia with increased and unregulated 1,25-dihydroxyvitamin D production in a neonate with subcutaneous fat necrosis. J Pediatr 1988; 112: 792–794.

28. Ricardo-Gonzalez R.R., Lin J.R., Mathes E.F., McCalmont T.H., Pincus L.B. Neutrophil-rich subcutaneous fat necrosis of the newborn: A potential mimic of infection. J Am Acad Dermatol 2016; 75(1): 177–185. DOI: 10.1016/j.jaad.2016.02.1151

29. Giulia R., Spagnut G., Morandi F., Valerio E., Cutrone M. Subcutaneous fat necrosis of the newborn. Clinical Case Reports 2015; 3(12): 1017–1020. DOI: 10.1002/ccr3.423

30. Lewis H.M., Ferryman S., Gatrad A.R., Moss C. Subcutaneous fat necrosis of the newborn associated with hypercalcemia. J R Soc Med 1994; 87: 482–483.

31. Kruse K., Irle U., Uhlig R. Elevated 1,25-dihydroxyvitamin D serum concentrations in infants with subcutaneous fat necrosis. J Pediatr 1993; 122: 460–463.


Review

For citations:


Kholodnova N.V., Mazankova L.N., Turina I.E., Volter A.A., Makarova L.M., Tsilinskaya O.V. SUBCUTANEOUS ADIPONECROSIS OF A NEWBORN. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2018;63(5):92-97. (In Russ.)

Views: 2894


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1027-4065 (Print)
ISSN 2500-2228 (Online)