Neonatal lupus
https://doi.org/10.21508/1027-4065-2018-63-5-88-91
Abstract
Neonatal lupus is a complex of symptoms diagnosed in newborns whose mothers suffer from autoimmune rheumatic diseases; it is manifested by two main signs: diseases of the skin and heart. A newborn may have classic ring-shaped erythema, telangiectasia, skin atrophy, follicular plugs and scales. This skin lesion is usually combined with a partial or complete heart block due to fibrosis of its pathways. There is a Clinical case of a child with neonatal lupus from own practice.
Conflict of interest: The authors of this article confirmed the lack of conflict of interest and financial support, which should be reported.
About the Authors
T. P. Makarova
Kazan State Medical University
Russian Federation
Russian Federation
Kh. M. Vakhitov
Kazan State Medical University
Russian Federation
Russian Federation
N. N. Firsova
Children’ Republican Clinical Hospital
Russian Federation
Russian Federation
Yu. S. Melnikova
Kazan State Medical University
Russian Federation
Russian Federation
T. A. Novitskaya
Kazan State Medical University
Russian Federation
Russian Federation
References
1. Кошелева Н.М., Алекберова З.С. Неонатальная волчанка. Современная ревматология 2015; 9(4): 92–97. [Kosheleva N.M., Alekberova Z.S. Neonatal lupus. Sovremennaya revmatologiya 2015; 9(4): 92–97 (in Russ)]
2. Weston W.L., Morreli J.G., Lee L.A. The clinical spectrum of anti-Ro-positive cutaneous neonatal lupus erythematosus. Am J Acad Dermatol 1999; 40: 675–681. DOI: 10.1016/ S0190-9622(99)70146-5
3. Thornton C.M., Eichenfield L.F., Shinall E.A., Siegfried E., Rabinowitz L.G., Esterly N.B. et al. Cutaneous telangiectases in neonatal lupus erythematosus. Am J Acad Dermatol 1995; 33: 19–25. DOI: 10.1016/01909622(95)90004-7
4. Petri M., Watson R., Hochberg M.C. Anti-Ro antibodies and neonatal lupus. Rheum Dis Clin North Am 1989; 15(2): 335–360.
5. Buyon J., Roubey R., Swersky S., Pompeo L., Parke A., Baxi L., Winchester R. Complete congenital heart block: risk of occurrence and therapeutic approach to prevention. J Rheumatol 1988; 15(7): 1104–1108.
6. Barclay C.S., French M.A., Ross L.D., Sokol R.J. Successful pregnancy following steroid therapy and plasma exchange in a woman with anti-Ro (SS-A) antibodies. Case report. Br J Obstet Gynaecol 1987; 94(4): 369–371. DOI: 10.1111/j.14710528.1987.tb03107.x
7. Kaaja R., Julkunen H., Ammälä P., Teppo A.M., Kurki P. Congenital heart block: successful prophylactic treatment with intravenous gamma globulin and corticosteroid therapy. Am J Obstet Gynecol 1991; 165(5 Pt 1): 1333–1334. DOI: 10.1016/ S0002-9378(12)90755-3.
8. Tran H.B., Ohlsson M., Beroukas D., Hiscock J., Bradley J., Buyon J.P., Gordon T.P. Subcellular redistribution of la/SSB autoantigen during physiologic apoptosis in the fetal mouse heart and conduction system: a clue to the pathogenesis of congenital heart block. Arthritis Rheum 2002; 46(1): 202–208. DOI: 10.1002/1529-0131(200201)46:13.0.CO;2-Y
Review
For citations:
Makarova T.P., Vakhitov Kh.M., Firsova N.N., Melnikova Yu.S., Novitskaya T.A. Neonatal lupus. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2018;63(6):88-91. (In Russ.) https://doi.org/10.21508/1027-4065-2018-63-5-88-91
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