Analysis of gene expression by nCounter Nanostring technology in medical research: experience with children with nephrotic syndrome
https://doi.org/10.21508/1027-4065-2019-64-1-110-115
Abstract
In the era of modern medicine, there are formed the fundamental scientific principles in the diagnosis of a wide range of diseases that are based on traditional instruments: laboratory and functional studies, light microscopy, immunofluorescence, and electron microscopy. However, in recent decades these methods have become insufficient to verify various variants of the diseases, especially with an atypical clinical picture. The article discusses the capabilities of the nCounter technology from the company Nanostring Technologies, it describes in detail the capabilities of the technology in the diagnosis of various diseases, and also the authors present their own experience of using diagnostics in children with nephrotic syndrome.
About the Authors
S. L. Morozov
Veltischev Research and Clinical Institute for Pediatrics
Russian Federation
Moscow.
Russian Federation
Moscow.
A. S. Voronkova
Veltischev Research and Clinical Institute for Pediatrics
Russian Federation
Moscow.
Russian Federation
Moscow.
V. V. Dlin
Veltischev Research and Clinical Institute for Pediatrics
Russian Federation
Moscow.
Russian Federation
Moscow.
T. I. Turkina
Pirogov Russian National Research Medical University
Russian Federation
Moscow.
Russian Federation
Moscow.
V. S. Sukhorukov
Pirogov Russian National Research Medical University; Research Center of Neurology
Russian Federation
Moscow.
Russian Federation
Moscow.
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Review
For citations:
Morozov S.L., Voronkova A.S., Dlin V.V., Turkina T.I., Sukhorukov V.S. Analysis of gene expression by nCounter Nanostring technology in medical research: experience with children with nephrotic syndrome. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2019;64(1):110-115. (In Russ.) https://doi.org/10.21508/1027-4065-2019-64-1-110-115
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