Ante- and postnatal diagnostics and complex treatment of congenital cytomegalovirus infection
N. V. Rogozina,
V. V. Vasilev,
A. A. Grineva,
A. V. Mikhailov,
T. A. Kashtanova,
A. N. Romanovskiy,
R. A. Ivanova,
E. S. Romanova,
G. M. Ushakova https://doi.org/10.21508/1027-4065-2019-64-6-89-93
Abstract
Timely diagnostics and treatment of cytomegalovirus infection in pregnant women and newborns allow to avoid serious consequences, preserving the life and health of the child. The article provides an example of antenatal diagnosis of congenital cytomegalovirus infection in the fetus (positive result of polymerase chain reaction in umbilical cord blood), treatment with umbilical transfusion of donor red blood cells, postnatal therapy with antiviral drugs, including ganciclovir and specific immunoglobulin. The issues of assessing the risk of congenital cytomegalovirus infection, approaches to its prevention and treatment during pregnancy are discussed.
About the Authors
N. V. Rogozina
Pediatric Research and Clinical Center for Infectious Diseases under the Federal Medical Biological Agency of the Russian Federation: St. Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation
Russian Federation
Saint-Petersburg
Russian Federation
Saint-Petersburg
V. V. Vasilev
Pediatric Research and Clinical Center for Infectious Diseases under the Federal Medical Biological Agency of the Russian Federation; North-Western State Medical University named after I.I. Mechnikov of the Ministry of Healthcare of the Russian Federation
Russian Federation
Saint-Petersburg
Russian Federation
Saint-Petersburg
A. A. Grineva
Pediatric Research and Clinical Center for Infectious Diseases under the Federal Medical Biological Agency of the Russian Federation
Russian Federation
Saint-Petersburg
Russian Federation
Saint-Petersburg
A. V. Mikhailov
North-Western State Medical University named after I.I. Mechnikov of the Ministry of Healthcare of the Russian Federation; St. Petersburg State Budgetary Healthcare Institution Maternity Hospital No. 17
Russian Federation
Saint-Petersburg
Russian Federation
Saint-Petersburg
T. A. Kashtanova
St. Petersburg State Budgetary Healthcare Institution Maternity Hospital No. 17
Russian Federation
Saint-Petersburg
Russian Federation
Saint-Petersburg
A. N. Romanovskiy
North-Western State Medical University named after I.I. Mechnikov of the Ministry of Healthcare of the Russian Federation; St. Petersburg State Budgetary Healthcare Institution Maternity Hospital No. 17
Russian Federation
Saint-Petersburg
Russian Federation
Saint-Petersburg
R. A. Ivanova
Pediatric Research and Clinical Center for Infectious Diseases under the Federal Medical Biological Agency of the Russian Federation; Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
Russian Federation
Saint-Petersburg
Russian Federation
Saint-Petersburg
E. S. Romanova
North-Western State Medical University named after I.I. Mechnikov of the Ministry of Healthcare of the Russian Federation
Russian Federation
Saint-Petersburg
Russian Federation
Saint-Petersburg
G. M. Ushakova
Pediatric Research and Clinical Center for Infectious Diseases under the Federal Medical Biological Agency of the Russian Federation
Russian Federation
Saint-Petersburg
Russian Federation
Saint-Petersburg
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Review
For citations:
Rogozina N.V., Vasilev V.V., Grineva A.A., Mikhailov A.V., Kashtanova T.A., Romanovskiy A.N., Ivanova R.A., Romanova E.S., Ushakova G.M. Ante- and postnatal diagnostics and complex treatment of congenital cytomegalovirus infection. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2019;64(6):89-93. (In Russ.) https://doi.org/10.21508/1027-4065-2019-64-6-89-93
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