Results of use of seawater spray with brown algae extract in the early postoperative period in children after adenotomy
https://doi.org/10.21508/1027-4065-2020-65-1-128-132
Abstract
Adenotomy is one of the most common surgeries on the part of ENT organs in childhood, it is usually performed under endotracheal anesthesia.
Purpose. To evaluate the effectiveness of the spray containing sea water and brown algae extract in the early postoperative period in children after adenotomy.
Characteristics of the children and research methods. 24 patients aged from 4 to 10 years (12 boys and 12 girls) were examined and treated in the Otorhinolaryngology Department of the Perm Regional Children’s Clinical Hospital. All patients underwent adenotomy due to hypertrophy of the pharyngeal tonsil of the II–III degree, they received antibiotics for 5 days after surgery. The patients were divided into 2 groups: Group 1 (study group, n=12) used, Aqualor Protect spray for irrigation therapy of the nasal cavity and nasopharynx; Group 2 (comparison group, n=12) used a spray with isotonic sodium chloride solution for irrigation therapy. 2 doses of saline solution were sprayed into each nostril 4 times for 4 days.
Results. According to the medical examination, the study group demonstrated more pronounced improvement of the following indicators (visual analogue scale scores): overall health (p<0.05), swelling of the nasal cavity (p<0.05), hyperemia of the mucous membrane of the nasal cavity (p<0.05), improved nasal breathing (p<0.034), the presence of mucous-hemorrhagic crusts in the nasal cavity (p<0.0001), general feelings (p<0.02).
Conclusion. The spray with seawater and brown algae extract is more effective than nasal spray with isotonic solution in the early postoperative period in children after adenotomy.
About the Authors
D. V. Konischev
Wagner Perm State Medical University
Russian Federation
Perm
Russian Federation
Perm
A. M. Elovikov
Wagner Perm State Medical University
Russian Federation
Perm
Russian Federation
Perm
A. I. Ivanov
Wagner Perm State Medical University
Russian Federation
Perm
Russian Federation
Perm
D. V. Shabunin
Regional Children’s Clinical Hospital
Russian Federation
Perm
Russian Federation
Perm
References
1. Лопатин А.С., Варвянская А.В., Осипова Е.А., Пелещенко Т.Г. Ирригационная терапия в ринологии: в поисках оптимального метода. Российская ринология 2018; 2 (1): 26–46. [Lopatin A.S., Varvyanskaya A.V.,
2. Osipova E.A., Peleshenko T.G. Irrigation therapy in rhinology: in search of the optimal method. Rossiiskaya rinologiya 2018; 2 (1): 26–46. (In Russ.)] DOI: 10.17116/ rosrino201826146-53
3. Queiroz K.C., Medeiros V.P., Queiroz L.S., Abreu L.R., Rocha H.A., Ferreira C.V. et al. Inhibition of reverse transcriptase activity of HIV by polysaccharides of brown algae. Biomed Pharmacother 2008; 62 (5): 303–307. DOI: 10.1016/j.biopha.2008.03.006
4. Hidari K.I., Takahashi N., Arihara M., Nagaoka M., Morita K., Suzuki T. Structure and anti-dengue virus activity of sulfated polysaccharide from a marine alga. Biochem Biophys Res Commun 2008; 376 (1): 91–95. DOI: 10.1016/j. bbrc.2008.08.100
5. Gao C., Li Y., Xing Y., Zhu H., Shen J., Tian J. Fucoidan, a sulfated polysaccharide from brown algae, against myocardial ischemia-reperfusion injury in rats via regulating the inflammation response. Food Chem Toxicol 2011; 49 (9): 2090–2095. DOI: 10.1016/j.fct.2011.05.022
6. Maruyama H., Tamauchi H., Hashimoto M., Nakano T. Suppression of Th2 immune responses by mekabu fucoidan from Undaria pinnatifida sporophylls. Int Arch Allergy Immunol 2005; 137 (4): 289–294. DOI: 10.1159/000086422
7. Maruyama H., Tamauchi H., Hashimoto M., Nakano T. Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida. Vivo 2003; 17 (3): 245–249.
8. Limmon G.V., Arredouani M., McCann K.L., Corn Minor R.A., Kobzik L., Imani F. Scavenger receptor class-a is a novel cell surface receptor for double-stranded RNA. FASEB J 2008; 22 (1): 159–167. DOI: 10.1096/fj.07-8348com
9. Florez N., Gonzalez-Munoz M.J., Ribeiro D., Fernandes E., Dominguez H., Freitas M. Algae Polysaccharides’ chemical characterization and their role in the inflammatory process. Curr Med Chem 2017; 24 (2): 149–175. DOI: 10.2174/092986732366616102
Review
For citations:
Konischev D.V., Elovikov A.M., Ivanov A.I., Shabunin D.V. Results of use of seawater spray with brown algae extract in the early postoperative period in children after adenotomy. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2020;65(1):128-132. (In Russ.) https://doi.org/10.21508/1027-4065-2020-65-1-128-132
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