Experience of respiratory syncytial virus infection prevention in high-risk neonatal infants in the Orenburg Region during the epidemic season

То prevent acute respiratory infections, related complications, and high death rates is one of the significant problems in the nursing of premature neonates, as well as infants with congenital heart diseases. Respiratory syncytial virus (RSV) infection characterized by a severe adverse outcome, primarily in high-risk children is particularly dangerous. The purpose of this investigation was to evaluate the efficiency of passive immunization with palivizumab (Synagis®) in neonatal and postneonatal periods in the Orenburg Region during the epidemic season. The infants were followed up in October 2013 to April 2014. Tolerability, morbidity, and mortality in the immunized infants and the organization of RSV-infection prevention in the region were analyzed. Immunoprophylaxis of RSV-infection was shown to be effective if healthcare facilities and services made well-coordinated and successive activities.

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