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A teenager with a severe form of COVID-19

https://doi.org/10.21508/1027-4065-2020-65-5-58-65

Abstract

In most cases children have a light form of new coronavirus infection COVID-19 as compared to adult patients; however, some children may develop severe forms of the disease. Children account for 1—11% of the confirmed patients, less than 1% of the patients have severe and extremely severe forms. The article describes a clinical case of a teenager with a severe course of COVID-19, characterized by the mismatch of physical data and a large degree of lung tissue damage, the development of hemorrhagic syndrome, low effectiveness of antibacterial and antiviral therapy, requiring Tocilizumab.

About the Authors

L. N. Mazankova
Russian Medical Academy of Continuous Professional Education
Russian Federation

Moscow



I. M. Osmanov
Bashlyaeva Children's Municipal Clinical Hospital
Russian Federation

Moscow



E. R. Samitova
Bashlyaeva Children's Municipal Clinical Hospital; Russian Medical Academy of Continuous Professional Education
Russian Federation

Moscow



A. B. Malakhov
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation


V. V. Koroid
Bashlyaeva Children's Municipal Clinical Hospital
Russian Federation

Moscow



А. A. Nedostoev
Bashlyaeva Children's Municipal Clinical Hospital
Russian Federation

Moscow



E. P. Kaurova
Bashlyaeva Children's Municipal Clinical Hospital
Russian Federation

Moscow



T. A. Kuznetsova
Bashlyaeva Children's Municipal Clinical Hospital
Russian Federation

Moscow



O. S. Kulichkina
Russian Medical Academy of Continuous Professional Education
Russian Federation

Moscow



N. V. Loban
Bashlyaeva Children's Municipal Clinical Hospital
Russian Federation

Moscow



References

1. Shekerdemian L.S. Mahmood N.R., Wolfe K.K., Riggs B.J., Ross C.E., McKiernan C.A. et al. Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatrics 2020. DOI: 10.1001/jamapedi-atrics.2020.1948

2. Temporary guidelines of the Ministry of Health of the Russian Federation “Prevention, diagnosis and treatment of new coronavirus infection (COVID-19)” Version 7 (03.06.2020) (in Russ.) https://static-0.rosminzdrav.ru/system/attach-ments/attaches/000/050/584/original/03062020_MR_COVID-19_v7.pdf

3. Brodin P. Why is COVID-19 so mild in children? Acta Paedi-atrica 2020; 109(6): 1082-1083. DOI: 10.1111/apa.15271

4. Lu X., Zhang L, Du H., Zhang J., Li J., Qu J. et al. SARS-CoV-2 Infection in Children. New Engl J Med 382(17): 1663-1665. DOI: 10.1056/NEJMc2005073

5. Tagarro A., Epalza C., Santos M., Sanz-Santaeufemia F. J., Otheo E., Moraleda C. Screening and Severity of Corona-virus Disease 2019 (COVID-19) in Children in Madrid. Spain. JAMA Pediatrics 2020. DOI: 10.1001/jamapediat-rics.2020.1346

6. Zimmermann P, Curtis N. Coronavirus infections in children including COVID-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children. Pediatr Infect Dis J 2020; 39(5): 355. DOI: 10.1097/INF.0000000000002660

7. Cao Q, Chen Y, Chen С, Chiub С. SARS-CoV-2 infection in children: Transmission dynamics and clinical characteristics. J Form Med Ass 2020; 119(3): 670. DOI: 10.1016/j.jfma.2020.02.009

8. Chan J.F., Yuan S., Kok K.H., To K.K., Chu H., Yang J. et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 2020; 395(10223): 514-523. DOI: 10.1016/S0140-6736(20)30154-9

9. Ludvigsson J.F. Systematic review of COVID-19 in children show milder cases and a better prognosis than adults. Acta Paediatrica 2020; 109(6): 1088-1095. DOI: 10.1111/apa.15270

10. Hagmann S. COVID-19 in children: More than meets the eye. Travel Med Infect Dis 2020. DOI: 10.1016/j.tmaid.2020.101649

11. Zhang Y.P. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China. Chin J Epidemiol 2020; 41: 145-151. DOI: 10.3760/cma.j.issn.0254-6450.2020.02.003

12. Xia W., Shao. J., Guo Y., Peng X., Li Z., Hu D. Clinical and CT features in pediatric patients with COVID 19 infection: Different points from adults. Pediatr Pulmonol 2020; 55(5): 1169-1174. DOI: 10.1002/ppul.24718

13. Hong H., Wang Y., Chung H.T., Chen C.J. Clinical characteristics of novel coronavirus disease 2019 (COVID-19) in newborns, infants and children. Pediatr Neonatol 2020; 61(2): 131-132. DOI: 10.1016/j.pedneo.2020.03.001

14. Dong Y., Mo X., Hu Y., Qi X., Jiang F., Jiang Z., Tong S. Epidemiology of COVID-19 Among Children in China. Pediatrics 2020; 145(6): e20200702. DOI: 10.1542/peds.2020-0702

15. Carlotti A.P.C.P., Carvalho W.B., Johnston C., Rodriguez I.S., Delgado A.F. COVID-19 Diagnostic and Management Protocol for Pediatric Patients. Clinics (Sao Paulo) 2020; 75: e1894. DOI: 10.6061/clinics/2020/e1894


Review

For citations:


Mazankova L.N., Osmanov I.M., Samitova E.R., Malakhov A.B., Koroid V.V., Nedostoev А.A., Kaurova E.P., Kuznetsova T.A., Kulichkina O.S., Loban N.V. A teenager with a severe form of COVID-19. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2020;65(5):58-65. (In Russ.) https://doi.org/10.21508/1027-4065-2020-65-5-58-65

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ISSN 1027-4065 (Print)
ISSN 2500-2228 (Online)