Chicken pox and pregnancy: risks to mother and fetus. Ways to solve the problem
https://doi.org/10.21508/1027-4065-2021-66-3-87-93
Abstract
Chickenpox is a common disease leading to a large number of clinical manifestations, ranging from mild spontaneously resolving forms to severe complicated cases requiring hospitalization and parenteral therapy. Despite the fact that this infection is benign in the majority of cases, it can lead to disseminated life-threatening processes in pregnant women and unimmunized newborns infected during the perinatal period, as well as it can cause intrauterine death and fetal abnormalities.
Currently, there are no unified therapeutic approaches in the management of pregnant women with chickenpox. The nature and severity of infection in children depends on the moment of infection (before or after birth, intrapartum), the immune status of the mother against the human herpesvirus type 3 (HHV-3), the gestational age of the fetus and the presence of concomitant conditions.
About the Authors
I. V. Koltsova
Gamaleya Federal Scientific Research Centre of Epidemiology and Microbiology
Russian Federation
Russian Federation
Moscow
Е. A. Domonova
Central Research Institute of Epidemiology
Russian Federation
Russian Federation
Moscow
О. Yu. Silveystrova
Central Research Institute of Epidemiology
Russian Federation
Russian Federation
Moscow
L. B. Kisteneva
Gamaleya Federal Scientific Research Centre of Epidemiology and Microbiology
Russian Federation
Russian Federation
Moscow
References
1. Санитарно-эпидемиологические правила СП 3.1.3525-18 «Профилактика ветряной оспы и опоясывающего лишая», утверждены постановлением Главного государственного санитарного врача от 05.02.2018 №12. [Sanitary and epidemiological rules SP 3.1.3525-18 «Prevention of chickenpox and shingles», approved by the decree of the Chief State Sanitary Doctor of the Russian Federation dated 05.02.2018 No. 12. (in Russ.)]
2. Rice M.E., Bannerman M., Marin M., Lopez A.S., Lewis M.M., Stamatakis C.E. et al. Maritime varicella illness and death reporting, U.S., 2010–2015. Travel Med Infect Dis 2018; 23:27–33. DOI: 10.1016/j.tmaid.2018.04.001
3. Center for Disease Control and Prevention (CDC) Varicella. Epidemiology and Prevention of Vaccine-Preventable Diseases. The Pink Book: Course Textbook – 13th ed 2015. https:// www.cdc.gov/vaccines/pubs/pinkbook/varicella.html. Ссылка активна на 01.04.2021
4. Инфекционная заболеваемость в Российской Федерации. Ссылка активна на 01.04.2021. [Infectious morbidity in the Russian Federation. https://rospotrebnadzor.ru/activities/statistical-materials/statictic. Link active on 04/01/2021. (in Russ.)]
5. О состоянии санитарно-эпидемиологического благополучия населения в Российской Федерации в 2019 году: Государственный доклад. М.: Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека, 2020; 299. https://www.rospotrebnadzor.ru/documents/details.php?ELEMENT_ID=14933. Ссылка активна на 01.04.2021. [On the state of sanitary and epidemiological well-being of the population in the Russian Federation in 2019: State report. Moscow: Federal Service for Supervision of Consumer Rights Protection and Human Well-being, 2020; 299. https://www.rospotrebnadzor.ru/documents/details.php?ELEMENT_ID=14933. Link active on 04/01/2021. (in Russ.)]
6. Bailey H. Screening for varicella in pregnancy. External review against programme appraisal criteria for the UK National Screening Committee (UKNSC). NSCUK National Screening Committee, 2015; 27
7. Schmid D.S., Jumaan A.O. Impact of varicella vaccine on varicella-zoster virus dynamics. Clin Microbiol Rev 2010; 23: 202–217. DOI: 10.1128/CMR.00031-09
8. Arvin A.M., Moffat J.F., Sommer M., Oliver S., Che X., Vleck S. et al. Review Varicella-zoster virus T cell tropism and the pathogenesis of skin infection. Curr Top Microbiol Immunol 2010; 342: 189–209. DOI: 10.1007/82_2010_29
9. Gershon A.A., Breuer J., Cohen J.I. Varicella zoster virus infection. Nat Rev Dis Primers 2015; 1: 15016. DOI: 10.1038/nrdp.2015.16
10. Lamont R.F., Sobel J.D., Carrington D., Mazaki-Tovi S., Kusanovic J.P., Vaisbuch E. et al. Varicella-zoster virus (chickenpox) infection in pregnancy. Romero RBJOG 2011; 118(10): 1155–1162
11. Kuchar E., Miskiewicz K., Szenborn L., Nitsch-Osuch А. Respiratory complications in children hospitalized with varicella. Adv Exp Med Biol 2013; 788: 97–102. DOI: 10.1007/978-94-007-6627-3_15
12. Колесникова С.М., Чижова Г.В. Врожденная и неонатальная ветряная оспа. Здравоохранение Дальнего Востока 2017; 3(73): 31–33. [Kolesnikova S.M., Chizhova G.V. Congenital and neonatal chickenpox. Zdravoohranenie Dal’nego Vostoka 2017; 3(73): 31–33. (in Russ.)]
13. Royal Colege of Obstetricians and Gyinaecologists. Chickenpox in Pregnancy: Green-top Guideline N.13. 2015. Database https://www.rcog.org.uk/en/guidelines-research-services/guidelines/gtg13/. Link active on 04/01/2021.
14. Клинические рекомендации «Ветряная оспа у взрослых» (утверждены решением пленума правления Национального научного общества инфекционистов 30 октября 2014 года. http://nnoi.ru/uploads/files/protokoly/Vetr_ospa. pdf. Ссылка активна на 01.04.2021. [Clinical guidelines «Chickenpox in adults» approved by the decision of the plenum of the Board of the Scientific Society of Infectious Diseases on October 30, 2014. http://nnoi.ru/uploads/files/protokoly/Vetr_ospa.pdf. Link active on 04/01/2021. (in Russ.)]
15. Watanabe M., Ochiai H., Ito M., Negoro M., Suga S., Ihara T. Laboratory Diagnosis of Breakthrough Varicella in Children. Pediatr Infect Dis J 2017; 36(6): 560–563. DOI: 10.1097/ INF.0000000000001475
16. Ayoade F., Kumar S. Varicella Zoster. In: StatPearls [Internet]. Treasure Island (FL). StatPearls Publishing, 2020. https://www.ncbi.nlm.nih.gov/books/NBK448191
17. Домонова Э.А. Инфекция, вызываемая вирусом варицелла–зостер. В кн.: Лабораторная диагностика инфекционных болезней. Под ред. В.Г. Акимкина, М.Г. Твороговой. М.: РИПОЛ классик, 2020; 507–514. [Domonova E.A. Infection caused by the Varicella-Zoster virus. In: Laboratory diagnostics of infectious diseases. V.G. Akimkin, M.G. Tvorogova (eds). Moscow: RIPOL classic, 2020; 507–514. (in Russ.)]
18. Pasternak B., Hviid A. Use of acyclovir, valacyclovir, and famciclovir in the first trimester of pregnancy and the risk of birth defects. JAMA 2010; 304(8): 859–866. DOI: 10.1001/jama.2010.1206
19. United States Centers for Disease Control and Prevention. Updated recommendations for use of VariZIG. Morbidity and Mortality Weekly Report 2013; 62(28): 1–23. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6228a4.htm. Link active on 04/01/2021
20. Blumental S., Lepage Ph. Management of varicella in neonates and infants. BMJ Paediatr Open 2019; 3(1): e000433. DOI: 10.1136/bmjpo-2019-000433
Review
For citations:
Koltsova I.V., Domonova Е.A., Silveystrova О.Yu., Kisteneva L.B. Chicken pox and pregnancy: risks to mother and fetus. Ways to solve the problem. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2021;66(3):87-93. (In Russ.) https://doi.org/10.21508/1027-4065-2021-66-3-87-93
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