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Outcomes of atopic dermatitis manifesting in the first year of life

https://doi.org/10.21508/1027-4065-2021-66-5-168-171

Abstract

For 10 years the authors analyzed 165 clinical cases of children with atopic dermatitis, which manifested in the first year of life. According to the 10-year follow-up, the authors revealed different outcomes of the disease, depending on the severity of the course, clinical forms of dermatitis and the timing of its onset. Favorable outcome with complete remission was observed in 30.9% of cases and was more common in children with a mild course of atopic dermatitis, acute exudative forms and with the onset of the disease at the age over 6 months. The transition to chronic forms was noted in 14.5% of cases and more often took place in children with a moderate severe course of the disease, erythematous-squamous forms and the onset of the disease at the age of 4–6 months. The development of respiratory forms of allergy (allergic rhinitis and bronchial asthma) was noted in 54.6% of cases and was more often detected in patients with a moderate severe and severe atopic dermatitis, erythematous-squamous forms and exudative forms with lichenification and onset of the disease in the first 3 months of life.

About the Authors

Kh. M. Vakhitov
Kazan State Medical University
Russian Federation

Kazan



I. N. Serdinskaya
Children’s City Polyclinic No.6
Russian Federation

Kazan



T. G. Malanicheva
Kazan State Medical University
Russian Federation

Kazan



References

1. Global atlas of allergy. Akdis C.A., Agache I. (eds). Zurich: EAACI, 2014; 388

2. Weidinger S., Novak N. Atopic dermatitis. Lancet 2016; 387(10023): 1109–1122. DOI: 10.1016/S0140-6736(15)00149-X

3. Smirnova G.I. Atopic dermatitis in children: new in pathogenesis, diagnosis and treatment. Lechashhii vrach 2017; 4: 12–19. (in Russ.)

4. Tamrazova O.B. Pathogenetic therapy of children suffering from severe forms of atopic dermatitis. RMJ 2013; 2(21): 108–114. (in Russ.)

5. Revyakina V.A. Stage therapy of atopic dermatitis in children. Consilium Medicum. Pediatriya 2015; 1: 50–53. (in Russ.)

6. Malanicheva T.G., Shamov B.A. The effectiveness of enterosgel in the correction of systemic endotoxinemia in children with atopic dermatitis. Pharmateca 2016; 1: 32–35. (in Russ.)

7. Balabolkin I.I. Atopy and allergic diseases in children. Pediatriya. Zhurnal im. G.N. Speranskogo 2003; 6:99–102. (in Russ.)

8. Allergology. R.M. Khaitov, N.I. Ilyina (eds). Moscow: GEOTAR-Media, 2009; 256. (in Russ.)

9. Warner J.O. A double–blinded, randomized, placebo-controlled trial of cetirizine in preventing the onset of asthma in children with atopic dermatitis: 18 months treatment and 18 months posttreatment follow-up. J Allergy Clin Immunol 2001; 108: 929–937

10. Kulig M., Bergmann R., Klettke U. Natural course of sensitization to food and inhalant allergens during the first 6 years of life. J Allergy Clin Immunol 1999; 103: 1173–1179

11. Spergel J.M., Paller A.S. Atopic dermatitis and the atopic march. to the J Allergy Clin Immunol 2003; 112 (6 Suppl): 8–17

12. Rhodes H.L, Sporik R., Thomas P., Holgate S.T., Cogswell J.J. Early life risk factors for adult asthma: a birth cohort study of subjects at risk. J Allergy Clin Immunol 2001; 108: 720–727

13. Oettgen H.C., Geha R.S. IgE regulation and roles in asthma pathogenesis. J Allergy Clin Immunol 2001; 107: 429–440

14. Kjellman B., Gustafsson P.M. Asthma from childhood to adulthood: asthma se-verity, allergies, sensitization, living conditions, gender influence and social consequences. Respir Med 2000; 94: 454–465


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For citations:


Vakhitov Kh.M., Serdinskaya I.N., Malanicheva T.G. Outcomes of atopic dermatitis manifesting in the first year of life. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2021;66(5):168-171. (In Russ.) https://doi.org/10.21508/1027-4065-2021-66-5-168-171

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ISSN 1027-4065 (Print)
ISSN 2500-2228 (Online)