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Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)

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Analysis of risk factors that determine the severity of transient tachypnea of the newborn and allow predicting treatment tactics

https://doi.org/10.21508/1027-4065-2022-67-2-71-75

Abstract

Transient tachypnea of the newborn is a parenchymal lung disease characterized by respiratory distress in the first hours after birth. The consequences of underestimating the severity of the disease, incorrectly chosen respiratory support technique or its untimely use at the stage of the delivery room are the increase in respiratory failure, transfer to the intensive care unit, and the need for more invasive and expensive methods of treatment. In the study, we set the task to determine the risk factors that allow us to predict the severity of the course of transient tachypnea of the newborn at the stage of the delivery room.

Purpose. Analysis of risk factors that determine the severity of transient tachypnea in the newborn and predicting the tactics of their treatment.

Methods. Retrospective analysis of full-term newborns (n = 201) diagnosed with transient tachypnea of the newborn in 2020, who received any type of respiratory support in the first hours of life.

Results. Most patients with transient tachypnea of the newborn required respiratory support at the stage of the delivery room, which we associate with a combination of risk factors in the history of pregnancy and childbirth. A high incidence of cerebral pathology in the studied newborns was revealed. According to our data, the following factors can be considered as predictors of the severity of the condition and hospitalization in the intensive care unit from the delivery room of patients with transient tachypnea of the newborn: delivery by Casarean section, low Apgar score at 1 and 5 minutes, Downs scale score of 4–5 points, and the need for respiratory support during the delivery room stage.

Conclusions. The results of the study proved a high frequency of transient tachypnea of the newborn registered in full-term infants, allowed to identify risk factors for a severe course of transient tachypnea of the newborn and hospitalization in the intensive care unit.  

About the Authors

O. P. Kovtun
Ural State Medical University
Russian Federation

Yekaterinburg



E. V. Shestak
Ural State Medical University; Yekaterinburg Clinical Perinatal Center
Russian Federation

Yekaterinburg



O. L. Ksenofontova
Yekaterinburg Clinical Perinatal Center
Russian Federation

Yekaterinburg



References

1. Volodin N.N. Neonatology National guidelines. Russian Association of Perinatal Medicine Specialists. Moscow: GEOTAR-Media, 2019; 750 (in Russ.)

2. Avery M.E., Gatewood O.B., Brumley G. Transient Tachypnea of Newborn. Am J Dis Child 1966; 111(4): 380–385. DOI: 10,1001/archpedi.1966,02090070078010

3. Sengupta S., Carrion V., Shelton J., Wynn R.J., Ryan R.M., Singhal K., Lakshminrusimha S. Adverse neonatal outcomes associated with early-term birth. JAMA Pediatr 2013; 167(11): 1053–1059. DOI: 10,1001/jamapediatrics.2013,2581

4. Moresco L., Romantsik O., Calevo M.G., Bruschettini M. Non-invasive respiratory support for the management of transient tachypnea of the newborn. Cochrane Database Syst Rev 2020; 4(4): CD013231. DOI: 10,1002/14651858.CD013231.pub2

5. Methodological letter of the Ministry of Health of the Russian Federation. ≪Resuscitation and stabilization of the condition of newborn babies in the delivery room≫. 2020. Ed. by prof. E.N. Baybarina (in Russ.) https://neonatology.pro/wp-content/uploads/2020/03/letter_resuscitation_newborn_delivery_2020.pdf/ Ссылка активна на 16.02.2022

6. Mostovoj A.V., Karpova A.L. Use of CPAP therapy in neonatology: from simple to complex. Detskie Bolezni Serdtsa i Sosudov 2015; 4: 13–23. (in Russ.)

7. Buchiboyina A., Jasani B., Deshmukh M., Patole S. Strategies for managing transient tachypnoea of the newborn — a systematic review. J Matern Neonatal Med 2017; 30(13): 1524– 1532. DOI: 10,1080/14767058,2016,1193143

8. Osman A.M., El-Farrash R.A., Mohammed E.H. Early rescue Neopuff for infants with transient tachypnea of newborn: a randomized controlled trial. J Matern Neonatal Med 2019; 32(4): 597–603. DOI: 10,1080/14767058,2017,1387531

9. Gizzi C., Klifa R., Pattumelli M.G., Massenzi L., Taveira M., Shankar-Aguilera S., De Luca D. Continuous Positive Airway Pressure and the Burden of Care for Transient Tachypnea of the Neonate: Retrospective Cohort Study. Am J Perinatol 2015; 32(10): 939–943. DOI: 10,1055/s-0034–1543988

10. Kayıran S.M., Erçin S., Kayıran P., Gursoy T., Gurakan B. Relationship between thyroid hormone levels and transient tachypnea of the newborn in late-preterm, early-term, and term infants. J Matern Neonatal Med 2019; 32(8): 1342– 1346. DOI: 10,1080/14767058,2017,1405386


Review

For citations:


Kovtun O.P., Shestak E.V., Ksenofontova O.L. Analysis of risk factors that determine the severity of transient tachypnea of the newborn and allow predicting treatment tactics. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2022;67(2):71-75. (In Russ.) https://doi.org/10.21508/1027-4065-2022-67-2-71-75

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ISSN 1027-4065 (Print)
ISSN 2500-2228 (Online)