Buy (150 RUB)
|Generate QR code
Open Access
Subscription or Fee Access
Analysis of risk factors for the formation of insufficiency and deficiency of vitamin D in children
https://doi.org/10.21508/1027-4065-2023-68-1-91-96
Abstract
The article discusses the main risk factors for the formation of insufficiency and deficiency of vitamin D in children. Particular attention is paid to the course and dietary preferences of the mother during pregnancy, the intake of vitamin and mineral complexes, the nutrition of the child after birth, the type of feeding, the subsidy of vitamin D preparations and complementary foods. 1246 children under four years of age with no history of vitamin D deficiency were examined. With clinical manifestations of rickets, 52 children were identified, who underwent determination of 25(OH) D in serum, while low availability was detected in 21.1%, vitamin D insufficiency — in 63.4% of children, deficiency — in 15.3% of cases. There was an interaction between the use of dairy products enriched with a vitamin-mineral complex containing vitamin D and Ca, the use of therapeutic doses of vitamin D, and an increase in the level of 25 (OH) D in the blood serum.
About the Authors
L. M. Panasenko
Novosibirsk State Medical University
Russian Federation
Russian Federation
Novosibirsk
Zh. V. Nefedova
Novosibirsk State Medical University
Russian Federation
Russian Federation
Novosibirsk
T. V. Kartseva
Novosibirsk State Medical University
Russian Federation
Russian Federation
Novosibirsk
Kh. A. Fadeeva
Novosibirsk State Medical University
Russian Federation
Russian Federation
Novosibirsk
D. A. Oladele
Novosibirsk State Medical University
Russian Federation
Russian Federation
Novosibirsk
N. V. Leonova
Children’s City Clinical Hospital No. 6
Russian Federation
Russian Federation
Novosibirsk
References
1. Romanenkova E.M., Zubkova N.A. Vitamin D-deficient rickets in a teenager: a clinical case. Russian Bulletin of Perinatology and Pediatrics. Rossiyskiy Vestnik perinatologii i pediatrii 2020; 65(4): 356–357. (in Russ.)
2. Rasulova N.A., Rasulov A.S., Sharipov R.X., AxmedovaM.M., Irbutaeva L.T. Assessment of the significance of the level of 25 (OH) D3 in blood serum and its effect on the prevention of rickets in children of the 1st year of life. Dostizheniya nauki i obrazovaniya 2019; 11(52): 45–49. (in Russ.)
3. Namazova-Baranova L.S., Zaharova I.N., Gromova O.A., Mal’cev S.V., Borovik T.Je., Pludovski P. et al. Vitamin D deficiency in children and teenagers of the Russian Federation: modern approaches to correction. Moscow: Pediatr, 2018; 96. (in Russ.)
4. Burt L.A., Gaudet S., Kan M., Rose S.M., Billington E.O., Boyd S.K. et al. Methods and procedures for: a randomized double-blind study investigating dose-dependent longitudinal effects of vitamin D supplementation on bone health. Contemporary Clinical Trials 2018; 67: 68–73. DOI: 10.1016/j.cct.2018.02.009
5. Stoffers A.J., Weber D.R., Levine M.A. An Update on Vitamin D Deficiency in the twenty-first century: nature and nurture. Curr Opin Endocrinol Diab Obes 2022; 29(1): 36–43. DOI: 10.1097/MED.0000000000000691
6. Misra M. Vitamin D insufficiency and deficiency in children and adolescents. https://www.uptodate.com/contents/vitamin-d-insufficiency-and-deficiency-in-children-and-adolescents /
7. Borovik T.Je., Gromova O.A., Zaharova I.N., Mal’cev S.V., Moshetova L.K., Namazova-Baranova L.S. et al. Vitamin D deficiency in children and teenagers of the Russian Federation: modern approaches to correction. Moscow: Pediatr, 2021; 116. (in Russ.)
8. Munns C.F., Simm P.J., Rodda C.P., Garnett S.P., Zacharin M.R., Ward L.M. et al. Incidence of vitamin D deficiency rickets among Australian children: an Australian Paediatric Surveillance Unit study. Med J Australia 2012; 196(7): 466–468. DOI: 10.5694/mja11.10662
9. Eremkina A. K., Mokrysheva N.G., Pigarova E.A., Mirnaja S.S. Vitamin D: effects on pregnancy, maternal, fetal and postnatal outcomes. Terapevticheskii arkhiv 2018; 90(10): 115–127. (in Russ.) DOI: 10.26442/terarkh201890104–127
10. Xiao L., Xing C., Yang Z., Xu S., Wang M., Du H. et al. Vitamin D supplementation for the prevention of childhood acute respiratory infections: a systematic review of randomised controlled trials. Br J Nutrition 2015; 114(7): 1026–1034. DOI: 10.1017/S000711451500207X
11. Lima M.S., Pereira M., Castro C.T., Santos D.B. Vitamin D deficiency and anemia in pregnant women: a systematic review and meta-analysis. Nutrition Кreviews 2022; 80(3): 428–438. DOI: 10.1093/nutrit/nuab114
12. Zajachnikova T.E., Belan Je.B., Krasil’nikova A.S. Vitamin D deficiency in the mother–placenta–fetus system as a risk factor for physical and neurological developmental disorder in premature infants. Russkii meditsinskii zhurnal. Medicinskoe obozrenie 2019; 3(5): 20–25. (in Russ.)
13. Dutra L.V., Affonso-Kaufman F.A., Cafeo F.R., Kassai M.S., Barbosa C.P., Santos Figueiredo F.W. et al. Association between vitamin D plasma concentrations and VDR gene variants and the risk of premature birth BMC Pregn Childbirth. 2020; 20(3): 1–11. DOI: 10.1186/s12884–019–2671–2
14. Belyh N.A., Amelina V.V. Significance of vitamin d deficiency in the format ion of bronchial obstructive syndrome in children. Nauka molodyh (EruditioJuvenium) 2019; 7(2): 261–273. (in Russ.) DOI: 10.23888/HMJ201972261–273
15. Shamansurova Je.A., Isahanova N.H. Frequent respiratory illnesses in children and vitamin D deficiency. Meditsina: teoriya i praktika 2019; 4(S): 606. (in Russ.)
16. Martineau A.R., Jolliffe D.A., Hooper R.L., Greenberg L., Aloia J.F., Bergman P. et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ 2017; 356: i6583. DOI:10.1136/bmj.i6583
17. Kazemain E., Ansari S., Davoodi S.H., Patterson W.B., Shakerinava P., Wagner C.L. et al. The Effect of Maternal Vitamin D Supplementation on Vitamin D Status of Exclusively Breastfeeding Mothers and Their Nursing Infants: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Advances in Nutrition 2022; 13(2): 568–585. DOI: 10.1093/advances/nmab126
18. Dawodu A., Salameh K.M., Al-Janahi N.S., Bener A., Elkum N. The effect of high-dose postpartum maternal vitamin D supplementation alone compared with maternal plus infant vitamin D supplementation in breastfeeding infants in a high-risk population. A randomized controlled trial. Nutrients 2019; 11(7): 1632.DOI: 10.3390/nu11071632
19. Kodencova V.M., Namazova-Baranova L.S., Makarova S.G. The national program for optimization of provision with vitamins and minerals of children in russia. Summary review of the document. Pediatricheskaya farmakologiya 2017; 14(6): 478–493. (in Russ.) DOI: 10.15690/pf.v14i6.1831
20. Baranov A.A., Tutel’jan V.A., Baturin A.K., Namazova-Baranova L.S., Borovik T.Je., Kon’ I.Ja. et al. National program for optimizing the nutrition of children aged 1 to 3 years in the Russian Federation. Moscow: Pediatric, 2015; 36. (in Russ.)
Review
For citations:
Panasenko L.M., Nefedova Zh.V., Kartseva T.V., Fadeeva Kh.A., Oladele D.A., Leonova N.V. Analysis of risk factors for the formation of insufficiency and deficiency of vitamin D in children. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2023;68(1):91-96. (In Russ.) https://doi.org/10.21508/1027-4065-2023-68-1-91-96
Views:
462
Email this article 