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Mitochondrial dynamics and the significance of its disturbances in the development of childhood diseases. Part II. Cardiological and endocrinological aspects
V. S. Sukhorukov,
T. I. Baranich,
A. V. Egorova,
E. N. Fedorova,
K. A. Skvortsova,
D. A. Kharlamov,
A. I. Krapivkin https://doi.org/10.21508/1027-4065-2024-69-2-12-18
Abstract
In recent years, the dynamics of mitochondrial transformations in cells have been of more concern to both representatives of basic science and researchers in the field of applied medicine. A growing number of observations demonstrate the important regulatory influence of mitochondrial dynamics on a variety of physiological and pathological processes in many, if not all, organ and tissue structures. The prospects for studying the features and regulators of these processes for understanding the pathogenesis of diseases, developing their new biomarkers, as well as treatment technologies seem increasingly significant. The purpose of this article is to review the facts obtained regarding mitochondrial dynamics, which, from the authors’ point of view, deserve the attention of pediatricians. The volume of relevant information turned out to be too extensive to fit into one article, which forced it to be divided into several successive publications. The second part provides information about the role of mitochondrial dynamics disturbances in the pathogenesis of cardiovascular and endocrine diseases in children.
About the Authors
V. S. Sukhorukov
Research Center of Neurology; Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
T. I. Baranich
Research Center of Neurology; Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
A. V. Egorova
Research Center of Neurology; Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
E. N. Fedorova
Research Center of Neurology; Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
K. A. Skvortsova
Research Center of Neurology; Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
D. A. Kharlamov
Voino-Yasenetsky Scientific and Practical Center for Specialized Medical Care for Children
Russian Federation
Russian Federation
Moscow
A. I. Krapivkin
Pirogov Russian National Research Medical University; Voino-Yasenetsky Scientific and Practical Center for Specialized Medical Care for Children
Russian Federation
Russian Federation
Moscow
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For citations:
Sukhorukov V.S., Baranich T.I., Egorova A.V., Fedorova E.N., Skvortsova K.A., Kharlamov D.A., Krapivkin A.I. Mitochondrial dynamics and the significance of its disturbances in the development of childhood diseases. Part II. Cardiological and endocrinological aspects. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2024;69(2):12-18. (In Russ.) https://doi.org/10.21508/1027-4065-2024-69-2-12-18
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