Umbilical cord blood glucose levels in full-term newborns
Abstract
The purpose of the investigation was to determine the umbilical cord venous blood level of glucose in full-term newborns and its relationship to the mode of delivery. The investigation included 102 full-term newborn infants, including 33 and 69 babies born via cesar-ean and vaginal delivery, respectively. Umbilical cord serum glucose levels were determined by the glucose oxidase test using a Sap-phire-400 biochemical analyzer. In healthy full-term newborns, the mean umbilical cord blood glucose levels were 4,29±0,88 mmol/1 (minimum, 2,9 mmol/1 and maximum, 5,9 mmol/1). In the babies born via cesarean delivery, the umbilical cord blood concentration of glucose was ascertained to be significantly lower than in those born vaginally (3,84+0,71 mmol/1 versus 4,51+0,87 mmol/1; /><0,0001). Abdominal delivery can be apparently considered to be a risk factor for hypoglycemia in neonatal infants.
About the Authors
A. L. Karpova
Saint Petersburg Pediatric Medical University
Russian Federation
Russian Federation
M. V. Narogan
V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Moscow
Russian Federation
Russian Federation
A. V. Mostovoy
Saint Petersburg Pediatric Medical University
Russian Federation
Russian Federation
O. M. Miroshnichenko
Regional Clinical Maternity Hospital, Veliky Novgorod
Russian Federation
Russian Federation
Yu. N. Nekipelova
Regional Clinical Maternity Hospital, Veliky Novgorod
Russian Federation
Russian Federation
N. Yu. Karpov
Saint Petersburg Pediatric Medical University
Russian Federation
Russian Federation
References
1. Неонатология. Национальное руководство. Под. ред. Н.Н. Володина. М: ГЭОТАР-Медиа 2007; 847. (Neonatology. National guidelines. Editor N.N. Volodin. M: GEOTAR-Media2007; 847.)
2. Рооз P., Генцель-Боровичеши О., Прокитте Г. Неонатология. Практические рекомендации. М: Медицинская литература 2011; 568. (Rooz R., Gencel'-Borovicheslii О., Prokitte G. Neonatology. Practical recommendations. M: Medicinskaja literatura 2011; 568.)
3. Шабалов Н.П. Неонатология. 4-е издание, в 2 томах. М: Медпресс-информ 2006. (Shabalov N.P. Neonatology. 4-е edition, in 2 volumes. M: Medpress-inform 2006.)
4. Osier F.H., Berkley J.A., Ross A. et al. Abnormal blood glucose concentrations on admission to a rural Kenyan district hospital: prevalence and outcome. Arch Dis Child 2003; 88: 7: 621-625.
5. Boardman J.P., Wusthoff C.J., Cowan F.M. Hypoglycaemia and neonatal brain injury. Arch Dis Child Educ Pract Ed 2013; 98: 2-6.
6. Postnatal Glucose Homeostasis in Late-Preterm and Term Infants Committee on Fetus and Newborn. Pediatrics 2011; 127: 575-579.
7. Gomella T.L. Neonatology: Management, Procedures, On-
8.
9.
10. Call Problems, Diseases, and Drugs. Sixth edition. McGraw-Hill, 2009; 894.
11. Gleason C.A., Devaskar S. U. Avery's diseases of the newborn. 9th Ed. Elsevier Saunders, 2011; 1520.
12. BirdJ.A., Spencer J.A.D., Mould Т., Symonds M.E. Endocrine and metabolic adaptation following caesarean section or vaginal delivery. Archives of Disease in Childhood 1996; 74: F132-F134.
13. Haw don J.M., Ward Platt M.P., Aynsley-Green A. Patterns of metabolic adaptation for preterm and term infants in the first neonatal week. Arch Dis Child 1992; 67: 357—365.
14. Marconi AM., Paolini C, Buscaglia M. et al. The impact of gestational age and fetal growth on the maternal-fetal glucose concentration difference. Obstet Gynecol 1996; 87: 937—942.
15. Wirds J.W., Duyn A.E.J., Geraerts S.D. et al. S100 protein content of umbilical cord blood in healthy newborns in relation to mode of delivery. Arch Dis Child Fetal Neonatal Ed2003;88:l:F67-F69.
16. Prior Т., Mullins E., Bennett P. et al. Umbilical artery blood analysis at the time of delivery: a comparison between babies born by different modes of delivery. Arch Dis Child Fetal Neonatal Ed 2013; 98: Suppl 1: A63.
Review
For citations:
Karpova A.L., Narogan M.V., Mostovoy A.V., Miroshnichenko O.M., Nekipelova Yu.N., Karpov N.Yu. Umbilical cord blood glucose levels in full-term newborns. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2014;59(2):54-56. (In Russ.)
Views:
2687
Email this article 