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Achievements and future prospects of molecular allergy diagnostics in pediatrics
https://doi.org/10.21508/1027-4065-2025-70-1-5-10
Abstract
Improvements in clinical approaches and innovative technological solutions in the field of molecular allergy diagnostics have fundamentally changed the tactics and strategy for managing children with allergic diseases. In particular, molecular allergy diagnostics is used to make decisions in cases of suspected food allergy; to assess the risks of life-threatening reactions; to optimize the elimination diet; to identify cross-reactivity; to diagnose inhalant allergies and determine their clinical significance;to provide optimal recommendations for reducing the exposure to inhalation allergens; to rationally select pharmacotherapy and allergen-specific immunotherapy; to predict the course of allergic disease, including the development of the atopic march. In addition, molecular allergy diagnostics is the foundation for establishing a system for preventing allergic diseases. In this article, we have tried to outline the main achievements and prospects of molecular allergy diagnostics application in pediatric practice.
Supporting agencies: The research work and the publication of its results had been carried out with the financial support from the Moscow City Government Grant for the Implementation of a Scientific and Practical Project in Medicine No. 0408–1.
About the Authors
A. N. Pampura
Veltischev Research and Clinical Institute for pediatrics and pediatric surgery at the Pirogov Russian National Research Medical University; Morozov Children’s City Hospital
Russian Federation
Russian Federation
Moscow
E. F. Zhukalina
Veltischev Research and Clinical Institute for pediatrics and pediatric surgery at the Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
M. A. Morenko
Morozov Children’s City Hospital
Kazakhstan
Kazakhstan
Moscow
O. P. Ussenova
Astana medical university
Kazakhstan
Kazakhstan
Astana
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Review
For citations:
Pampura A.N., Zhukalina E.F., Morenko M.A., Ussenova O.P. Achievements and future prospects of molecular allergy diagnostics in pediatrics. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2025;70(1):5-10. (In Russ.) https://doi.org/10.21508/1027-4065-2025-70-1-5-10
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