Intellectual development of children born to women with a history of recurrent miscarriages
Abstract
Recently, there have been many publications on the assessment of the health and development of children born after in vitro fertilization (IVF) in the families with fertility problems. The purpose of the investigation was to determine the level of intellectual development in the children born in the families with a history of miscarriage. The database consisted of 71 children born after lymphocy-totherapy in the families with reproductive losses. The children's intellectual development was evaluated by the method developed by D. Wechsler. The findings were compared with the testing data on 1,700 children of the same age in central Russia. According to the results obtained, the intellectual development of children born after lymphocytotherapy in the families with reproductive losses did not significantly differ from its population-based indicators. No association was found between the course of pregnancy and severe intelligence disorders in the examinees. The higher educational level of families with reproductive losses versus the population-based level can be inferred to be a factor for the better social adaptation of families who create better conditions for their children to develop.
About the Authors
B. G. Ginzburg
Kaluga Regional Clinical Hospital
Russian Federation
Russian Federation
E. N. Kalitko
Kaluga State Institute of Educational Modernization
Russian Federation
Russian Federation
References
1. Ги Y.H., Wang N., Jin F. Long-term follow-up of children conceived through assisted reproductive technology. J Zhejiang Univ Sci В 2013; 14: 5: 359-371.
2. Hansen M., Kurincz.uk J.J., MilneE. et al. Assisted reproductive technology and birth defects: a systematic review and meta-analysis. Hum Reprod Update 2013; 19: 4: 330—353.
3. Leunens Г., Celestin-Westreich S., Bonduelle M. et al. Follow-up of cognitive and motor development of 10-year-old singleton children born after ICSI compared with spontaneously conceived children. Hum Reprod 2008; 23: 1: 105-11.
4. Гинзбург Б.Г., Гинзбург Е.Б., Глазков П.В. Лимфоцитотера-пия при невынашивании беременности. Акуш и гинекол 2005; 1: 48—50. (Ginzburg B.G., Ginzburg E.B., Glazkov RV. Lymphocytotherapy for miscarriage. Akush i ginekol 2005; 1:48-50.)
5. Филимоненко Ю.И., Тимофеев В.И. Тест Векслера. Диагностика уровня развития интеллекта (детский вариант). Методическое руководство. Ст-Петербург: ИМАТОН 2006; 112. (Filimonenko Y.I., Timofeev V.I. Wechslertest. Diagnosis of the level of intellectual development (children's version). Guidance. St-Petersburg: IMATON 2006; 112.)
6. Kaplan R.M., Saccuzzo D.P. Psychological Testing: Principles, Applications, and Issues. Wadsworth, Cengage Learning 2009; 752.
7. Zhang X.W., Huang Y, Xiang Y. et al. A twin study on intelligence and processing speed heritability of children and adolescent. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2009; 26: 3: 326-330.
8. Sandra R., Richard H., David W. The biological basis of injury and neuroprotection in the fetal and neonatal brain. Int J Dev Neurosci 2011; 29: 6: 551-563.
9. Middelburg K.J., Heineman M.J., Bos A.F., Hadders-Algra M. Neuromotor, cognitive, language and behavioral outcome in children born following IVF or ICSI—a systematic review. Hum Reprod 2008; 14: 219—231.
10. Knoester M., Helmerhorst F.M., Vandenbroucke J.P. et al. Cognitive development of singletons born after intracytoplasmic sperm injection compared with in vitro fertilization and natural conception. Fertil Steril 2008; 90: 289—296.
11. ZhuJX., Basso O., ObelC. etal. Infertility, infertility treatment and psychomotor development: the Danish national birth cohort. Paediatr Perinat Epidemiol 2009; 23: 98—106.
12. Ponjaert-Kristoffersen I., Bonduelle M., Barnes J. et al. International collaborative study of intracytoplasmic sperm injection-conceived, in vitro fertilization-conceived, and naturally conceived 5-year-old child outcomes: cognitive and motor assessments. Pediatrics 2005; 115: e283—289.
13. Tudwig A.K., Sutcliffe A.G., Diedrich K, Tudwig M. Post-neonatal health and development of children born after assisted reproduction: a systematic review of controlled studies. Eur J Obstet Gynecol Reprod Biol 2006; 127: 3—25.
14. Carson C, Kelly Y, Kurincz.uk J.J. et al. Effect of pregnancy planning and fertility treatment on cognitive outcomes in children at ages 3 and 5: longitudinal cohort study. BMJ 2011; 26: 343: d4473.
15. Carson C, Redshaw M., Sacker A. et al. Effects of pregnancy planning, fertility, and assisted reproductive treatment on child behavioral problems at 5 and 7 years: evidence from the Millennium Cohort Study. Fertil Steril 2013; 99: 2: 456—463.
16. Дружинин В.Н. Психология общих способностей. Ст-Петербург: Питер 2006; 83—108. (Druzhinin V.N. Psychology of general abilities. St-Petersburg: Piter 2006; 83—108).
Review
For citations:
Ginzburg B.G., Kalitko E.N. Intellectual development of children born to women with a history of recurrent miscarriages. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2014;59(2):99-102. (In Russ.)
Views:
567
Email this article 